IBMS/ECTS 2001 - PROGRAM and ABSTRACTS

POSTER SESSION 1

Wednesday, 6 June, 2001
12:30 - 14:00

The abstract text of poster presentations (prefix P) can be found in the Abstracts section. Click on the Abstract number.
Posters relating to the Wednesday Short Communication session will also be attended during this period.

Bone, Cartilage and Connective Tissue Matrix

P1 W
THE CUT 2000 – A NEW CEMENTLESS HIP SYSTEM WITH METAPHYSICAL ANCHORAGE

J. Scholz*, J. Osel

Auguste-Victoria Teaching Hospital, Center for Orthopaedic Surgery, Berlin, Germany

 
P4 W
EXIST SEX-RELATED DIFFERENCES OF BUA AND SOS OF THE OS CALCIS IN CHILDREN AND ADOLESCENTS?

B. Wuensche*, K. Wuensche, H. Faehnrich, R. Venbrocks, W. A. Kaiser

Clinic of Orthopaedics, University Jena, Germany; Institute of Radiology, University Jena, Germany

 
P7 W
EFFECT OF DEPHOSPHORYLATION OF DENTIN PHOSPHOPHORYN ON APATITE INDUCTION

T. Saito*, K. Matsuda, Y. Miyamoto, T. Uemura, M. A. Crenshaw

Health Sciences, Univ. of Hokkaido, Tobetsu, Hokkaido, Japan; NAIR; JST; Univ.of North Carolina

 
P10 W
DETECTION AND LOCALIZATION OF OSTEOCALCIN (BGP OR BONE GLA PROTEIN) IN TELEOSTS BY IN SITU HYBRIDATION AND IMMUNOHISTOCHEMISTRY

P. J. Gavaia*, C. A. Viegas, J. P. Pinto, M. C. Sarasquete, M. L. Cancela

CCMar, Universidade do Algarve, Campus de Gambelas, 8000-810 Faro, Portugal; Instituto de Ciencias Marinas de Andalucía (CSIC), Polígono Río San Pedro, 11510, Puerto Real, Cádiz, Spain

 
P13 W
THE USE OF FLUORESCENCE ACTIVATED CELL SORTING TO ANALYSE MATRIX VESICLES FROM EPIPHYSEAL GROWTH CARTILAGE

I. Schoenmakers*, B. M. Gadella, P. R. van Weeren, J. F. H. M. Brouwers, A. Barneveld, L. M. G. van Golde, C. H. A. van de Lest

Department of Biochemistry, Cell Biology and Histology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands; Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, The Netherlands

 
P16 W
MOLECULAR EVENTS CAUSED BY CYCLIC STRETCH IN SPINAL LIGAMENT CELLS FROM PATIENTS WITH OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENTS

M. Tanno*, K. Furukawa, K. Ueyama, S. Harata, S. Motomura

Dept. of Orthopaedic Surgery, Hirosaki University School of Medicine, Hirosaki, Japan; Dept. of Pharmacology, Hirosaki University School of Medicine, Hirosaki, Japan

 
P19 W
LACK OF ENDOCHONDRAL OSSIFICATION IN LONG BONES OF GROWING FROGS

T. Mori-ishi*, Y. Shibata, A. Yamaguchi

Department of Oral Pathology, Nagasaki university School of Dentistry, Nagasaki, Japan

 
P22 W
MICRODAMAGE DISTRIBUTION AND ALTERED MESSENGER RNA GENE EXPRESSION IN THE PROXIMAL FEMUR

N. Fazzalari*, J. Kuliwaba, D. Findlay, M. Forwood

Institute of Medical and Veterinary Science; Adelaide University; University of Queensland

 
P25 W
EFFECT OF TP508, A SYNTHETIC THROMBIN PEPTIDE, ON CBFA1, VEGF, COLLAGEN TYPE II EXPRESSION DURING FEMORAL FRACTURE HEALING

H. Wang*, J. Convery, C. Fowler, J. T. Ryaby

OrthoLogic

 
P28 W
PENTADECAPEPTIDE BPC-157 INCREASED ACHILE TENDOM HEALING AFTER UNILATERAL TRANSECTION IN THE RAT

M. Staresinic*, B. Sebecic, T. Sosa, S. Jadrijevic, L. Patrlj, D. Perovic, G. Aralica, S. Seiwerth, N. Kokic, P. Sikiric

Department of Surgery, Clinical Hospital "Merkur", Zagreb, Croatia; Departments of Pathology, School of Medicine, University of Zagreb, Zagreb, Croatia; Department of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb, Croatia; Departments of Pharmacology, School of Medicine, University of Zagreb, Zagreb, Croatia

 
P31 W
HISTOMORPHOMETRIC ANALYSIS IN ILIAC BONE OF NORMAL KOREAN INDIVIDUALS

K. B. Lee*, J. H. Kim, S. J. Kim, K. M. Yang, H. Y. Lee

Ajou University School of Medicine, Suwon, Korea; National Institute of Scientific Investigation, Seoul, Korea

 
P34 W
THE ALTERNATIVELY SPLICED EIIIA SEGMENT IS PREFERENTIALLY EXPOSED TO ANTIBODY RECOGNITION IN AN OSTEOARTHRITIC SYNOVIAL FLUID FIBRONECTIN FRAGMENT SPECIES

J. H. Peters*, S. Carsons, K. Kalunian, M. Yoshida, F. Ko, S. McDougall, T. J. Hahn

GRECC, West Los Angeles VA Medical Center, Los Angeles, CA, USA; UCLA School of Medicine, Los Angeles, CA, USA; Sacramento VA Medical Center, Mather, CA, USA; Winthrop University Hospital, Mineola, NY, USA

 
P37 W
EXPRESSION OF HEPARAN SULFATE PROTEOGLYCAN CORE PROTEINS DURING IN VITRO-DIFFERENTIATION OF OSTEOBLAST-LIKE CELLS

H. Hausser*, R. Brenner

Division for Biochemistry of Joint and Connective Tissue Diseases, University of Ulm, Ulm, Germany

 
P40 W
BIOMECHANICAL PROPERTIES OF FEMORAL SHAFTS IN INMATURE RATS WITH HYPOBARIA-INDUCED HYPOXEMIA

R. M. Alippi*, M. D. Meta, C. Bozzini, M. I. Olivera, J. L. Ferretti, C. E. Bozzini

Department of Physiology, Faculty of Odontology, University of Buenos Aires, Argentina

 
P43 W
BMU-COUPLING IS REGULATED BY LOCAL PATTERNS OF FLUID FLOW

E. H. Burger*, T. H. Smit, J. M. Huyghe

ACTA - Vrije Universiteit, Amsterdam, The Netherlands; Vrije Universiteit Medical Center, Amsterdam, The Netherlands; Technical University Eindhoven, The Netherlands

 
P46 W
ZINC STAINING OF MATRIX METALLOPROTEINASES AND ENDONUCLEASES IN GROWTH CARTILAGE

S. Gomez

Dept Anatomia Patologica, Faculty of Medicine, University of Cadiz, Spain

 
P49 W
DISTRIBUTIONS OF MRNAS FOR BMP-2 AND BMP RECEPTOR IN OSTEOARTHRITIC CARTILAGE

T. Miyaji*, T. Nakase, T. Tomita, M. Kaneko, K. Takahi, A. Myoui, K. Kuriyama, M. Horiki, H. Yoshikawa

Department of Orthopaedic Surgery, Osaka University Medical School, Osaka, Japan

 
P52 W
BONE MORPHOGENETIC PROTEIN EXPRESSION IN DIFFERENTIATING OSTEOBLASTS IS REGULATED BY PARATHYROID HORMONE

S. Martinovic*, V. Kisic, F. Borovecki, S. Vukicevic

Department of Anatomy, School of Medicine, University of Zagreb, Zagreb, Croatia

Diseases of Bone

P55 W
FELINE HEAD AND NECK SQUAMOUS CELL CARCINOMA LINE: CHARACTERIZATION, PRODUCTION OF PARATHYROID HORMONE-RELATED PROTEIN, AND REGULATION BY TRANSFORMING GROWTH FACTOR-BETA

S. H. Tannehill-Gregg, E. Ahaus, T. J. Rosol*

The Ohio State University, Columbus, OH, USA

 
P58 W
REGULATION OF PTHrP GENE EXPRESSION: A PATTERNS OF DNA METHYLATION IN BREAST CANCER CELL LINES

M. Rousière, C. Cataisson, J. Foley, J. Taboulet, Z. Bouizar*

U.349, Centre Viggo Petersen, Hôpital Lariboisière, 2 rue Ambroise Paré, Paris, France.; Medical Sciences, Indiana University School of Medicine, Bloomington, IN, USA

 
P61 W
RECOMBINANT HUMAN RANK LIGAND (RANKL) AND MACROPHAGE COLONY-STIMULATING FACTOR (M-CSF) FAIL TO RESCUE HUMAN INFANTILE OSTEOCLAST-POOR OSTEOPETROSIS (OP) IN VITRO

H. M. Massey, C. G. Steward, C. Wilson, A. Vellodi, M. A. Horton, A. M. Flanagan*

Royal Free and University College London Medical School, London, UK; Royal Hospital for Sick Children, Bristol, UK; Great Ormond Street Hospital, London, UK; Bone and Mineral Centre, University College, London, UK

 
P64 W
HYPOPHOSPHATEMIC HYPOPARATHYROIDISM AND RICKETS WITH CALCIUM SUPPLEMENTATION AND HYPOCALCITRIOLIC HYPERPARATHYROIDISM AND OSTEOCHONDROSIS WITH CALCIUM AND PHOSPHORUS SUPPLEMENTATION IN YOUNG DOGS

I. Schoenmakers*, G. Voorhout, C. S. Carlson, J. A. Mol, D. Richardson, H. A. W. Hazewinkel

Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands; Department of Veterinary Diagnostic Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA; Hill's Science and Technology Center, Topeka, Kansas, USA

 
P67 W
FOOT ALGO-DISTROPHIC, POST-TRAUMATIC SYNDROME: ISSUES AND POSTURE MODIFICATIONS

F. M. Donelli

No affiliations

 
P70 W
THE CHANGES OF SERUM FGF-2 LEVELS FOLLOWING BONE MARROW TRANSPLANTATION: IMPACT ON BONE MINERAL DENSITY

M. I. Kang*, W. Y. Lee, E. S. Oh, K. W. Oh, J. H. Han, B. Y. Cha, K. W. Lee, H. Y. Son, S. K. Kang, C. C. Kim

The Catholic University of Korea, College of Medicine, Seoul, Korea

 
P73 W
BONE MINERAL DENSITY (BMD), BIOCHEMICAL MARKERS AND FRACTURES IN PERITONEAL DIALYSIS (PD) PATIENTS

A. L. Negri*, M. Alvarez Quiroga, M. Bravo, A. Marino, E. E. Fradinger, C. E. Bogado, J. R. Zanchetta

Instituto de Investigaciones Metablicas, Buenos Aires, AR; RTC Argentina, Suc. Caballito, Buenos Aires, AR

 
P76 W
CIRCULATING OSTEOPROTEGERIN (OPG) IS AN UREMIC TOXIN TO CAUSE BONE AND PARATHYROID DISORDERS IN DIALYSIS PATIENTS

J. J. Kazama

Niigata University, Niigata, Japan; Kobe University, Kobe, Japan; National Sakura Hospital, Chiba, Japan; Tokyo Jikeikai Medical School, Tokyo, Japan; Tokai University, Kanagawa, Japan

 
P79 W
CLINICAL STUDY ABOUT THE RELATIONSHIP BETWEEN DIABETES AND OSTEOPOROSIS

P. S. Li*, H. Qian, H. Jiang

Department of Gerontology, 304 Hospital, Beijing 100037, China

 
P82 W
HIGH PREVALENCE AND INCIDENCE OF VERTEBRAL DEFORMITIES IN ANKYLOSING SPONDYLITIS PATIENTS WITH HYPERKYPHOSIS

P. P. M. M. Geusens*, D. Vosse, D. van der Heijde, J. Vanhoof, J. Raus, S. van der Linden

Department of Rheumatology, University Hospital, Maastricht, The Netherlands; Biomedical Research Institute, Limburg University Centre, Diepenbeek, Belgium

 
P85 W
EXPRESSION OF BONE INDUCING FACTORS IN RATS WITH OR WITHOUT A TIBIA FRACTURE AFTER TRAUMATIC BRAIN INJURY

U. Scherbel*, J. Khurana, C. T. Born, P. Riess, W. G. DeLong

University of Pennsylvania, Department of Orthopaedic Surgery; University of Cologne, Department of Surgery II; University of Pennsylvania, Department of Pathology; University of Pennsylvania, Department of Neurosurgery

 
P88 W
ANTHROPOMETRIC DIAGNOSIS OF "TRUE" OSTEOPENIA IN CAPD PATIENTS BASED ON DEXA-ASSESSED MUSCLE-BONE RELATIONSHIPS

A. Negri*, J. L. Ferretti, G. Cointry, J. R. Zanchetta

Instituto de Investigaciones Metabolicas, Buenos Aires, Argentina

 
P91 W
HYPERCALCEMIA AND OSTEOMALACIA COMPLICATED BY OSTEOPETROSIS CAUSED BY HIGH CONCENTRATION OF FLUORIDE AND ALUMINIUM IN CHILDREN

F. C. Li

The Hygieme Anti-epidemic Station of Liu Panshui City, Guizhou, 553000

 
P94 W
CHARACTERISATION AND PARTIAL PURIFICATION OF PHOSPHATE UPTAKE INHIBITORY ACTIVITY OF CONDITIONED MEDIUM FROM A SECOND ONCOGENIC OSTEOMALACIA TUMOUR CELL LINE

A. E. Nelson*, M. Mirams, O. Ljunggren, E. A. Martin, R. S. Mason, B. G. Robinson

Cancer Genetics, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, Australia; Physiology Department, Institute of Biomedical Research, University of Sydney, Sydney, Australia; Department of Internal Medicine, University Hospital, Uppsala, Sweden

 
P97 W
AN OCHRONOSIS CASE ASSOCIATED WITH SPINAL CHANGES SIMILAR TO ANKYLOSING SPONDYLITIS AND HIP OSTEOPENIA

Y. Sermez*, G. Fidan, N. Oruç, N. Karabulut

Pamukkale University, Department of Endocrinology and Metabolism, Denizli, Turkey; Pamukkale University, Department of Radiology Department, Denizli, Turkey

 
P100 W
CELLULAR ORIGIN AND OSTEOLYTIC ACTIVITY OF THE UNICAMERAL BONE CYST

F. Y. Lee*, G. Osgood, M. Parisien, H. M. Dick

Columbia University, USA

 
P103 W
FIFTEEN TO SEVENTEEN YEAR FOLLOW UP OF THE UNCEMENTED SPONGIOSA METAL SURFACE (SMS) TOTAL HIP ARTHROPLASTY

J. Scholz*, D. Hubalek, J. Osel, C. Höptner

Auguste-Victoria Teaching Hospital, Center for Orthopaedic Surgery, Berlin, Germany

 
P106 W
CANDIDATE GENES FOR DEGENERATIVE JOINT DISEASE IN PIGS

D. Jefferies*, J. Thompson, W. Smith, E. Seawright, C. Farquharson, C. Whitehead

Bone Biology Group, Roslin Institute, Roslin, UK; SAC Veterinary Services, Penicuik, UK; SAC Veterinary Science Division, Aberdeen, UK

 
P109 W
AGE DEPENDENT DEMISE OF MUTATED STEM CELLS AND "NORMALIZATION" OF FIBROUS DYSPLASIA OF BONE

P. Bianco*, S. A. Kuznetsov, M. Riminucci, N. Cherman, L. W. Fisher, M. T. Collins, S. Wientroub, P. G. Robey

Universita "La Sapienza", Rome, Italy; CSDB, NIDCR, NIH, Bethesda, MD, USA; Universita dell'Aquila, L'Aquila, Italy; Tel Aviv Medical Center, Tel Aviv, Israel

 
P112 W
SEQUENCE ANALYSIS OF MEASLES VIRUS NUCLEOCAPSID TRANSCRIPTS IN PATIENTS WITH PAGET'S DISEASE

S. V. Reddy, W. E. Friedrichs, G. D. Roodman*

Univ TX HSC @ SA, San Antonio, TX, USA

 
P115 W
SEVERITY OF PAGET'S DISEASE IN THE UK: IS IT DECLINING?

G. I. Al-Bahrani*, R. S. Lawson, M. C. Prescott, M. Davies, P. L. Selby

Department of Nuclear Medicine, Manchester Royal Infirmary, Manchester, UK; Musculoskeletal Research Group, University of Manchester, Manchester, UK

 
P118 W
BISPHOSPHONATE (OLPADRONATE) RETENTION AND ITS DETERMINANTS IN PAGET'S DISEASE OF BONE

S. C. L. M. Cremers*, E. Eekhoff, S. M. van Dam, J. Hartigh, N. A. T. Hamdy, P. Vermeij, S. E. Papapoulos

Leiden University Medical Center, Department of Clinical Pharmacy and Toxicology; Leiden University Medical Center, Department of Endocrinology

 
P121 W
LOW BONE DENSITY IS ASSOCIATED WITH REDUCED LEAN SOFT TISSUE MASS IN PROSTATE CANCER PATIENTS TREATED WITH ANDROGEN ABLATION

Z. Chen*, P. T. Nguyen, M. J. Maricic, F. R. Ahmann, B. L. Dalkin

University of Arizona

 
P124 W
EFFECT OF ESTROGEN AND CALCITRIOL REPLACEMENT IN BONE MASS IN RATS WITH RENAL FAILURE IN LONG AND SHORT-TERM ESTROGEN DEPRIVATION

M. Naves*, C. Díaz-Corte, C. Gómez, S. Braga, M. T. Fernández-Coto, M. Serrano, A. González, A. Rodríguez, J. B. Cannata

Bone and Mineral Research Unit. Instituto Reina Sofía de Investigación, Oviedo, Spain; Biochemistry Unit, Hospital Central de Asturias, Oviedo, Spain

Genetics

P127 W
POLYMORPHISMS IN THE ANDROGEN AND ESTROGEN RECEPTOR ALPHA GENES ARE ASSOCIATED WITH BMD IN MIDDLE-AGED FINNISH MEN

T. Remes*, S. B. Väisänen, J. Huuskonen, A. Mahonen, I. M. Penttilä, P. Mäenpää, H. Kröger, R. Rauramaa

Department of Biochemistry, University of Kuopio, Finland; Kuopio Research Institute of Exercise Medicine and Department of Physiology, University of Kuopio, Finland; Department of Clinical Chemistry, Kuopio University Hospital, Finland; Department of Surgery, Kuopio University Hospital, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Finland

 
P130 W
A LARGE CONSANGUINEOUS OSTEOPOROSIS FAMILY WITH 20 AFFECTED INDIVIDUALS

P. Dincer, B. O. Yildiz*, B. Balci, M. Bayraktar

Hacettepe University Faculty of Medicine Dept of Medical Biology, Ankara, Turkey; Hacettepe University Faculty of Medicine Dept of Internal Medicine Division of Endocrinology, Ankara, Turkey

 
P133 W
THERE IS NO ASSOCIATION BETWEEN THE POLYMORPHISM OF ESTROGEN RECEPTOR GENE AND TRANSSEXUAL MEN

M. Sosa*, A. Torres, E. Salido, E. Arbelo, Y. Barrios, M. C. Navarro, P. Betancor

University of Las Palmas de GC, Hospital University Insular. Bone Metabolic Unit; Investigation Unit, University of La Laguna; University of Las Palmas de Gran Canaria, Department of Nursery

 
P136 W
COLLAGEN TYPE I ALPHA 1 SP1 POLYMORPHISM, OSTEOPOROSIS AND OSTEOARTHRITIS IN OLDER MEN AND WOMEN

S. M. F. Pluijm*, H. W. van Essen, N. Bravenboer, A. G. Uitterlinden, J. H. Smit, P. Lips

Institute for Research in Extramural Medicine (EMGO-Institute), Vrije Universiteit, Amsterdam, The Netherlands; Endocrinology, Academic Hospital, Vrije Universiteit, Amsterdam, The Netherlands; Department of Internal Medicine III, Erasmus University Medical School, Rotterdam, The Netherlands; Department of Sociology and Social Gerontology, Vrije Universiteit, Amsterdam, The Netherlands

 
P139 W
APOLIPOPROTEIN E GENOTYPE INFLUENCES BONE LOSS AND BIOCHEMICAL MARKERS OF BONE TURNOVER IN ELDERLY POSTMENOPAUSAL WOMEN

J. K. Scariano*, P. J. Garry, G. Montoya, R. N. Baumgartner

University of New Mexico School of Medicine, Albuquerque, New Mexico, USA

Hormones and Cytokines

P142 W
THE EFFECT OF CALCITONIN ON HEALING OF TENDON INJURIES. FOLLOW-UP OF TENDON HEALING WITH MRI, HISTOLOGICAL EVALUATION AND MECHANICAL TESTING. EXPERIMENTAL STUDY IN RABBITS

H. Petrou*, T. Karachalios, L. Khaldi, K. Kalogera, G. P. Lyritis

Athens University, KAT Hospital, Kifissia, Greece; Laboratory for the Research of the Musculoskeletal Systeme

 
P145 W
HIGH EXTRACELLULAR GLUCOSE CONCENTRATION ENHANCES THE SENSITIVITY OF THE CALCIUM-SENSING RECEPTOR

H. Kanazawa*, H. Tanaka, M. Inoue, Y. Seino

Okayama University Medical School, Okayama, Japan

 
P148 W
INCREASED CALCIUM-SENSING RECEPTOR EXPRESSION IN CALCIUM-SUPPLEMENTED RATS WITH RENAL FAILURE

B. D. Kuizon*, I. B. Salusky, D. Shoback, E. Cambay, H. Jueppner, W. G. Goodman

UCLA School of Medicine, Los Angeles, USA; Endocrine Research Unit, VA Medical Center, San Francisco, USA; Endocrine Unit, Massachusetts General Hospital, Boston, USA

 
P151 W
MARKERS OF BONE RESORPTION IN PATIENTS WITH BREAST CANCER RECEIVING PAMIDRONATE

E. Terpos*, J. Palermos, M. Vassilaki, G. Papadopoulos, G. Vaiopoulos, J. Meletis

First Department of Internal Medicine, University of Athens Medical School, Laiko General Hospital, Athens, Greece; Department of Immunology, 251 General Air Force Hospital, Athens, Greece; "Hygeia" Hospital, Athens, Greece; Department of Medical Oncology, 251 General Air Force Hospital, Athens, Greece

 
P154 W
HISTOMORPHOMETRIC ANALYSIS OF BONE REMODELLING IN PATIENTS WITH METASTATIC BREAST CARCINOMA

S. Vukmirovic Popovic*, N. R. Colterjohn, S. Lhotak, W. C. M. Duivenvoorden, G. Singh

Department of Pathology and Molecular Medicine, McMaster University, Hamilton; Hamilton Health Sciences Corporation; Hamilton Regional Cancer Centre, Cancer Care Ontario; Hamilton, Ontario, Canada

 
P157 W
THE PRELIMINARY STUDY OF RELATIONSHIP BETWEEN MALIGNANT TUMOUR AND OSTEOPOROSIS

M. H. Bai

The Orthopaedics Institute of Lanzhou General Hospital, PLA, 730050, PR China

 
P160 W
PROTECTION OF NORMAL HUMAN BONE CELLS FROM APO2L/TRAIL AND CHEMOTHERAPEUTIC DRUG COMBINATION-INDUCED APOPTOSIS

D. M. Findlay*, S. Bouralexis, G. J. Atkins, F. Chai, S. Hay, M. T. Clayer, A. Evdokiou

Dept. of Orthopaedics and Trauma, Royal Adelaide Hospital, The University of Adelaide, Adelaide, SA, Australia; Dept. of Medicine, Dept. Orthopaedics, The Queen Elizabeth Hospital, The University of Adelaide, Woodville, SA, Australia

 
P163 W
BONE SIALOPROTEIN EXPRESSION IN CELL LINES OF HUMAN BREAST AND PROSTATE CANCER

B. Fohr*, M. F. Young, L. W. Fisher

Department of Medicine I, University of Heidelberg, Germany; Craniofacial and Skeletal Diseases Branch, NIDCR, NIH, Bethesda, MD, USA

 
P166 W
CLINICAL EVALUATION OF A NEW ASSAY FOR URINARY L-GALACTOSYLHYDROXYLYSINE (L-GHL): A PROMISING MARKER FOR CANCER PATIENTS

J. C. Dumon*, N. Kheddoumi, F. Journé, R. B. Boga, J. Mistry, J. J. Body

Laboratory of Endocrinology and Breast Cancer; Diagnostic Systems Laboratories, Inc., Webster, TX 77598, USA

 
P169 W
COMPARATIVE STUDY OF THE SENSITIVITY OF BIOCHEMICAL MARKERS OF BONE TURNOVER IN PATIENTS WITH BONE METASTASES FROM BREAST CANCER

J. C. Dumon*, B. Siwek, N. Kheddoumi, F. Journé, J. Barlé, J. J. Body

Laboratory of Endocrinology and Breast Cancer Research and Clinical Chemistry

 
P172 W
INTERLEUKIN-6 EXPRESSION IN OSTEOBLASTIC CELLS IS MODULATED BY BOTH HOMOLOGOUS AND HETEROLOGOUS MECHANISMS INVOLVING PARATHYROID HORMONE-RELATED PROTEIN

C. Guillen*, P. Martinez, M. E. Martinez, N. Del Valle, P. Esbrit

Bone and Mineral Metabolism Lab. Fund J Díaz; Research Unit, Hosp. La Paz; Biochemistry Division, Hosp. La Paz

 
P175 W
CYTOKINES, OSTEOPROTEGERIN AND OSTEOPROTEGERIN-LIGAND IN VITRO AND HISTOMORPHOMETRIC INDICES OF BONE FORMATION IN PATIENTS WITH DIFFERENT BONE DISEASES

H. Siggelkow*, T. Eidner, G. Lehmann, V. Viereck, D. Raddatz, G. Hein, M. Hüfner

Dep. for Gastroenterology and Endocrinology, University Hospital of Goettingen, Germany; Dep. of Internal Medicine, Friedrich-Schiller- University, Jena, Germany; Dep. of Obstetrics and Gynecology, University Hospital of Goettingen, Germany

 
P178 W
ANALYSIS BY DIFFERENTIAL DISPLAY PCR OF THE MOLECULAR MECHANISM BY WHICH LEUKEMIA INHIBITORY FACTOR MEDIATES INHIBITION OF OSTEOPROGENITOR CELL DIFFERENTIATION

D. Falconi*, J. Dreisziger, M. Kwok, J. E. Aubin

Department of Anatomy and Cell Biology, University of Toronto, Toronto, Ontario M5S 1A8, Canada

 
P181 W
INCREASED LEVELS OF THE STIMULATORY IGF BINDING PROTEIN-5 (IGFBP-5) IN EXTRACTS OF BONE MATRIX FROM OSTEOARTHRITIS AND PAGET'S DISEASE

S. J. Brown*, S. Mohan, P. Magnusson, M. W. J. Davie, C. A. Sharp

Charles Salt Research Centre, Oswestry, UK; Musculoskeletal Disease Center, JL Pettis VA Medical Center, Loma Linda, USA; Chester Centre for Stress Research, Chester, UK

 
P184 W
PTH AMELIORATES THE ACIDOSIS-INDUCED SKELETAL GROWTH INHIBITION VIA THE INSULIN-LIKE GROWTH FACTOR 1 (IGF1)

G. Maor*, R. Goldberg, J. Green

Technion, Haifa, Israel; Department of Nephrology, Rambam Medical Center, Haifa, Israel

 
P187 W
PERIPHERAL PTH1 RECEPTOR GENE DELIVERY IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR) DOES NOT AFFECT BLOOD PRESSURE BUT INCREASES PLASMA RENIN ACTIVITY

S. Fritsch, T. Massfelder, M. Grima, N. Taesch, A. Eichinger, B. Escande, M. Barthelmebs, J. J. Helwig*

University Louis Pasteur Medical School, E 0015 INSERM, Strasbourg, France; University Louis Pasteur Medical School, Department of Pharmacology, Strasbourg, France

 
P190 W
EARLY PHASE OF CALCIPENIA-INDUCED PARATHYROID HORMONE SECRETION IS BLUNTED IN PERFUSED PARATHYROID GLANDS OF STREPTOZOTOCIN-DIABETIC RATS

O. Mokuda*, R. Okazaki, Y. Sakamoto

Teikyo University, Ichihara, Japan

 
P193 W
LONG-TERM STUDY OF FUNCTIONALLY AND VIABILITY OF RAT AND HUMAN PARATHYROID GLANDS

M. Naves*, J. Menárguez, J. R. Polo, R. Jofré, J. Anguita, M. T. Fernández-Coto, J. L. Fernández-Martín, J. B. Cannata

Bone and Mineral Research Unit. Instituto Reina Sofía de Investigación, Oviedo, Spain; Biochemistry Unit. Hospital Central de Asturias, Oviedo, Spain; Hospital Universitario Gregorio Marañón, Madrid, Spain

 
P196 W
CHARACTERISATION OF THE EFFECTS OF DEXAMETHASONE ON MOUSE BONES

F. McLaughlin*, J. MacKintosh, B. Hayes, A. McLaren, P. L. Salmon, J. A. Humphreys, G. Brown, S. Farrow

Cell Biology, GlaxoWellcome Medicines Research Centre, Stevenage, UK; Respiratory Systems, GlaxoWellcome Medicines Research Centre, Stevenage, UK; AEA Technology, Harwell, Didcot, Oxfordshire, UK

Osteoblasts

P199 W
ANALYSIS OF 17BETA-ESTRADIOL, RALOXIFENE AND GENISTEIN STIMULATED HUMAN OSTEOBLAST CELLS USING THE GENECHIP DNA MICROARRAY TECHNOLOGY

M. Heim*, J. Shantz, O. Frank, P. Fuchs, C. Riegger, P. Weber, W. Hunziker, I. Martin, I. Bendik

Hoffmann-La Roche Ltd, Vitamins & Fine Chemicals Division, Department VFHF, CH-4070 Basel, Switzerland; Hoffmann-La Roche Ltd, Vitamins & Fine Chemicals Division, Department VFH, CH-4070 Basel, Switzerland; Research Division, Department of Surgery, University Hospital Basel, Switzerland

 
P202 W
ADRENOMEDULLIN AND ADRENOMEDULLIN RECEPTOR MRNA EXPRESSION IN OSTEOBLAST-LIKE CELLS. DEXAMETHASONE EFFECT

E. Diampaka, M. A. Denne, M. C. de Vernejoul, M. Cressent*

U.349 Inserm Hôpital Lariboisière, Paris, France

 
P205 W
MICRO- AND NANOSTRUCTURE OF MINERALISED TISSUE IN MICE OVEREXPRESSING THE TRANSCRIPTION FACTOR FRA-1

P. Roschger*, W. Tesch, K. Matsuo, W. Jochum, E. F. Wagner, P. Fratzl, K. Klaushofer

Ludwig Boltzmann Institute of Osteology, 4th Medical Department, Hanusch Krankenhaus and Unfallkrankenhaus Meidling, Vienna, Austria; Erich Schmid Institute of Materials Science, Austrian Academy of Sciences and University of Leoben, Leoben, Austria; Research Institute of Molecular Pathology (I.M.P.), Vienna, Austria

 
P208 W
CERIVASTATIN INDUCES BONE-SPECIFIC GENE EXPRESSION IN STROMAL PREADIPOCYTES

W. Carley*, S. Phan

Bayer Research Center, West Haven, CT, USA

 
P211 W
FGF2 AND FGFR-2 SIGNALING STIMULATED RUNX2 EXPRESSION

H. M. Ryoo*, H. J. Kim, M. H. Park, H. I. Shin, H. J. Kim

Kyungpook National University, Taegu, Korea

 
P214 W
LEPTIN CONTROL OF BONE METABOLISM: DIRECT OR INDIRECT ACTION?

B. A. J. Evans*, C. Elford, J. W. Gregory

Department of Child Health, University of Wales College of Medicine, Heath Park, Cardiff, UK

 
P217 W
CHARACTERIZATION OF CELL LINES DERIVED FROM PERIODONTAL LIGAMENT

T. Yoshizawa*, Y. Saito, M. Ikegame, O. Ishibashi, H. Yoshie, M. Obinata, H. Kawashima

Niigata University, Niigata, Japan; Tohoku University, Miyagi, Japan

 
P220 W
ISOLATION AND CHARACTERIZATION OF EQUINE OSTEOCALCIN

B. Carstanjen*, R. Wattiez, H. Amory, O. M. Lepage, B. Remy

Department of Large Animal Medicine, University of Liège, Sart-Tilman, Belgium; Service de Chimie Biologique, Université de Mons, Hainaut, Belgium; Département Hippique, Ecole Nationale Vétérinaire de Lyon, Marcy l'Etoile, France; Département de Physiologie de la Reproduction, Université de Liège, Sart-Tilman, Belgium

 
P223 W
MICROGRAVITY ACCELERATES DIFFERENTIATION, INDUCES APOPTOSIS AND STIMULATES INTERLEUKIN 6 EXPRESSION IN OSTEOBLAST-LIKE CELLS

N. Rucci*, S. Migliaccio, A. Taranta, A. Teti

Department of Experimental Medicine, University of L'Aquila, L'Aquila, Italy; Department of Histology and Medical Embryology, University "La Sapienza", Rome, Italy; Department of Medical Physiopathology, University "La Sapienza", Rome, Italy; Istituto Dermopatico dell'Immacolata, Rome, Italy

 
P226 W
ROLE OF MECHANICAL STRESS ON CULTURED SPINAL LIGAMENT CELLS DERIVED FROM PATIENTS WITH OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENTS INVESTIGATED BY THE MRNA DIFFERENTIAL DISPLAY TECHNIQUE

K. Iwasaki*, K. Furukawa, M. Tanno, K. Ueyama, S. Harata, S. Motomura

Department of Orthopedic Surgery Hirosaki University School of Medicine, Hirosaki, Japan; Department of Pharmacology Hirosaki University School of Medicine, Hirosaki, Japan

 
P229 W
INTRACELLULAR PRODUCTION OF CGMP STIMULATES THE DIFFERENTIATION OF OSTEOBLASTIC CELLS

H. Hagiwara*, E. Otsuka, A. Koyama, A. Inoue

Tokyo Institute of Technology, Yokohama, Japan

 
P232 W
ROLE OF P53 AND MDM-2 IN OSTEOBLAST DIFFERENTIATION

N. Chandar*, S. Bovenkerk, M. Nerney

Department of Biochemistry, Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL, USA

 
P235 W
POTENTIAL OSTEOGENESIS IN A NOVEL POROUS HYDROXYAPATITE COMBINED WITH TRANSPLANTED BONE MARROW DERIVED OSTEOBLASTIC CELLS

J. Dong*, H. Kojima, T. Uemura, M. Kikuchi, T. Tateishi, J. Tanaka

National Institute for Advanced Interdisciplinary Research (NAIR), Tsukuba, Japan; Shanghai Medical University, Shanghai, P.R.China; CREST JST (Japan Science and Technology); National Institute for Research in Inorganic Materials (NIRIM), Tsukuba, Japan; University of Tokyo, Tokyo, Japan

 
P238 W
EFFECTS PRODUCED BY BONE ALLOGRAFT MATRIX ON HUMAN OSTEOBLAST PROLIFERATION AND INTERLEUKIN-6 AND PROCOLLAGEN-I SYNTHESIS

L. Rodriguez de Acuña*, C. García-Moreno, C. De la Piedra, C. Vicario, S. Arlandis, L. López-Durán, M. L. Traba

Fundación Jiménez Díaz, Laboratorio de Bioquímica, Madrid, Spain.; Hospital Clínico San Carlos, Traumatología y Cirugía Ortopédica, Madrid, Spain

 
P241 W
EFFECTS OF PERIODIC PULSED ELECTROMAGNETIC FIELD STIMULATION ON PROLIFERATION, DIFFERENTIATION AND BONE-LIKE MATRIX MINERALIZATION IN OSTEOBLASTS IN DIFFERENT MATURATIONAL STAGES

P. Diniz*, K. Shomura, K. Soejima, G. Ito

Kagoshima University Dental School, Kagoshima, Japan

 
P244 W
HIGH-RESOLUTION MORPHOMETRIC AND TOPOGRAPHIC ANALYSIS OF HUMAN OSTEOBLASTIC CELL ADHESION ON ORTHOPEDIC ALLOYS FUNCTIONALIZED BY ADHESIVE PEPTIDES - A QUANTITATIVE 2D AND 3D ANALYSIS

A. Guignandon*, N. Boutahar, R. Bareille, Y. Usson, S. Verrier, L. Vico, C. Alexandre, J. Amédée

INSERM EM9901, J Monnet University, St-Etienne, France; DyOGen, Institut A. Bonniot, Grenoble, France; U443 INSERM, Bordeaux, France

 
P247 W
CELL-MATRIX INTERFACE IN BONE

A. Boyde

University College London, London, UK

 
P250 W
ALENDRONATE INTERACTS WITH THE INHIBITORY EFFECT OF 1,25(OH)₂D₃ ON PTHrP EXPRESSION IN HUMAN OSTEOBLASTIC CELLS

L. Gomez-Garcia*, M. Garcia-Flores, P. Sabando, A. Valin, L. Carreño, P. Esbrit, M. E. Martinez

Biochemistry Division .La Paz Hospital; Rheumatology Division. Princesa Hospital; Bone and Mineral Metabolism Laboratory, Fundación Jiménez Díaz; Rheumatology Division Gregorio Marañón Hospital

 
P253 W
INVOLVEMENT OF INAD AND TRPC3-LIKE PROTEIN IN THE 1,25-DIHYDROXY-VITAMIN D₃-INDUCED-CAPACITATIVE CATION ENTRY IN ROS 17/2.8 OSTEOBLASTIC-LIKE CELLS

C. Baldi*, G. Vazquez, R. L. Boland

Dept. Biologia, Bioquimica & Farmacia - Universidad Nacional del Sur, Bahia Blanca, Buenos Aires, Argentina

 
P256 W
ZINC MAPPING IN OSTEOBLASTS AND BONE MATRIX

S. Gomez

Dept Anatomia Patologica, Faculty of Medicine, University of Cadiz, Spain

 
P259 W
ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA PATHWAY STIMULATES OSTEOBLASTIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS

T. Xu*, A. Billin, D. Morris, T. Willson, L. Miller

Glaxo Wellcome Research and development, Reseach Triangle park, NC, USA

Osteoclasts

P262 W
THE MECHANISM OF RGD-INSULIN ANTI-OSTEOCLASTIC BONE RESORPTION

Y. Xue*, D. Li

Department of Biochemistry, Beijing Ji Shui Tan Hospital, Beijing, P.R. China

 
P265 W
OSTEOCLAST DIFFERENTIATION FACTOR IS DOMINANT IN CONTROLLING THE EXTENT OF BONE RESORPTION

N. Fazzalari*, J. Kuliwaba, G. Atkins, M. Forwood, D. Findlay

Institute of Medical and Veterinary Science; Adelaide University; University of Queensland

 
P268 W
EFFECTS OF THE NATURAL AND ARTIFICIAL MENSTRUAL CYCLE ON SECRETION OF BONE RESORPTIVE CYTOKINES IN WHOLE-BLOOD CULTURES

B. Abrahamsen, L. Nickelsen*, V. Bonnevie, H. Beck-Nielsen

Dept of Endocrinology, Odense Univ. Hospital, Odense, Denmark; Dept. of Medical Biology, Univ. of South Denmark, Odense, Denmark

 
P271 W
LIMITED RANKL EXPOSURE IN VITRO INDUCES OSTEOCLASTOGENESIS IN HUMAN PBMC

G. C. Nicholson, C. J. Aitken, J. M. Hodge, W. R. Holloway, T. Gough, F. Collier, M. A. Kirkland, D. E. Myers*

Department of Medicine, University of Melbourne, The Geelong Hospital; The Douglas Hocking Institute, The Geelong Hospital, Barwon Health

 
P274 W
P2 RECEPTOR STIMULATION UPREGULATES EXPRESSION OF OSTEOCLAST DIFFERENTIATION FACTOR (ODF) BY HUMAN OSTEOBLASTS

K. A. Buckley*, J. A. Gallagher, W. B. Bowler

Human Bone Cell Research Group, Department of Human Anatomy and Cell Biology, New Medical School, Ashton Street, University of Liverpool, L69 3GE, UK

 
P277 W
EXPRESSION OF OSTEOCLASTOGENIC MARKERS IN INFLAMED SYNOVIAL TISSUES IN PROSTHESIS LOOSENING AND ARTHRITIS

A. Sabokbar*, A. Pocock, O. Kudo, S. D. Neale, E. Schulze, L. Danks, N. A. Athanasou

University of Oxford, Oxford, UK

 
P280 W
OSTEOCLAST SIZE CORRELATES WITH DIFFERENCES IN RESORPTIVE ACTIVITY

J. N. M. Heersche*, R. Lees, M. F. Manolson, V. Sabharwal

Faculty of Dentistry, University of Toronto, Toronto, Canada

 
P283 W
FOLLOWING OF INTRACELLULAR VESICLE TRAFFIC IN LIVING OSTEOCLASTS USING CONFOCAL MICROSCOPY

J. Vaaraniemi*, H. K. Vaananen

Institute of Biomedicine, Department of Anatomy, University of Turku, Finland

 
P286 W
ACTIVATED ENDOTHELIUM RECRUITS OSTEOCLAST PRECURSORS FROM PERIPHERAL BLOOD

N. W. A. McGowan*, E. J. Walker, S. H. Ralston, M. H. Helfrich

Bone Research Group, Dept. of Medicine and Therapeutics, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, UK

 
P289 W
CONNEXIN-MIMETIC PEPTIDE GAP 27 DECREASES OSTEOCLASTIC ACTIVITY

J. Ilvesaro*, P. Tavi, J. Tuukkanen

University of Oulu, Finland

 
P292 W
THE EFFECT OF CLODRONATE METABOLISM ON THE INTRACELLULAR ATP CONCENTRATION IN RAW 264 MACROPHAGES

H. Mönkkönen*, S. Niva, M. J. Rogers, J. Mönkkönen

Department of Pharmaceutics, University of Kuopio, Finland; Department of Medicine and Therapeutics, University of Aberdeen, UK

 
P295 W
BONE RESORPTION IS DECREASED IN VITRO BY 17B ESTRADIOL AND RALOXIFENE FROM HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS

M. A. Burde*, Ph Couttet, D. Saintier, M. C. de Vernejoul, M. E. Cohen-Solal

INSERM U349, Paris, France

 
P298 W
FUNCTIONAL ROLE OF IONOTROPIC NON-NMDA RECEPTORS IN OSTEOCLAST RESORPTIVE ACTIVITY

M. Mukhida*, R. Gilbert, Y-F. Chen, G. I. Anderson

Dalhousie University, Halifax, Nova Scotia, Canada

Osteoporosis: Diagnosis

P301 W
YOUNG ADULT BONE MINERAL DENSITY IN CROATIA

S. Cvijetic*, S. Bolanca, D. Dekanic

Institute for Medical Research and Occupational Health, Ksavesrka cesta 2, Zagreb, Croatia

 
P304 W
BONE MINERAL DENSITY IN LUMBAR SPINE AND FEMORAL NECK IN THE FEMALE POPULATION OF MOSCOW

N. V. Toroptsova*, N. V. Demin, L. I. Benevolenskaya

Institute of Rheumatology, Moscow, Russia

 
P307 W
MENOPAUSAL AGE AND BMI INFLUENCE CORRELATION BETWEEN LUMBAR AND FEMORAL BMD

M. Di Stefano*, I. Grosso, F. Navone, C. Roggia, S. Casalis, G. C. Isaia

Department of Internal Medicine - University of Torino, Italy

 
P310 W
INFLUENCE OF DIFFERENT DXA DEVICES ON DETECTION OF OSTEOPOROSIS IN PATIENTS SAMPLE

P. Kasalicky*, J. Rosa, J. Kocian

Postgraduate Medical School, Ist Med.Clin.; MEDISCAN densitometric center; Reumatologic institute

 
P313 W
ELECTROALGOMETRY. DECREASE OF SKIN IMPEDANCE AS A MEASURE OF BONE AND JOINT PAIN

T. Fujita*, Y. Fujii, A. Miyauchi, Y. Takagi

Calcium Research Institute, Osaka, Japan; Katsuragi Hospital, Osaka, Japan; National-Hyogo Chuo Hospital, Hyogo, Japan

 
P316 W
APPLYING A SIMPLE CLINICAL TOOL TO IDENTIFY OSTEOPOROSIS AMONG JAPANESE WOMEN

S. Fujiwara*, N. Masunari, G. Suzuki, B. Sedrine, J. Y. Reginster

Radiation Effects Research Foundation, Hiroshima, Japan; WHO Collaborating Center for Public Heath Aspects of Rheumatic Disorders, Liege, Belgium

 
P319 W
VALIDATION OF A SIMPLE CLINICAL TOOL TO IDENTIFY ASIAN WOMEN WITH OSTEOPOROSIS

R. Rajatanavin*, K-S. Tsai, S-P. Chan, A. Kung, Q-R. Huang, M-I. Kang, S. B. Chionh, W. Ben Sedrine, J-Y. Reginster, The Osteoporosis Risk Assessment Tool for Asia Research Group

World Health Organization Collaborating Center for Public Health Aspects of Rheumatism

 
P322 W
DETERMINATION OF CA ISOTOPE RATIOS IN METABOLIC STUDIES USING SECTOR FIELD INDUCTIVELY COUPLED PLASMA MASS SPECTROMETER (HR-ICP-MS)

M. P. Field, M. Cifuentes, R. M. Sherrell, S. A. Shapses*

Rutgers University, New Brunswick, USA

 
P325 W
BONE MINERAL DENSITY AND BODY COMPOSITION ASSESSMENT IN CLINICAL PRACTICE

T. O. Chernova

Russian Endocrinology Research Centre, Moscow

 
P328 W
DETERMINATION OF BONE MINERAL DENSITY OF LIMBS AND PELVIC IN NORMAL SUBJECTS OF HENAN PROVINCE

Z. C. Liu*, X. H. Wang

Henan Electric Hospital, Zheng Zhou 450052, China

 
P331 W
FRACTURE CASE HISTORY AT OSTEOPOROSIS, RELATION TO CURRENT RESULTS IN THE QCT AND PQCT

K. Abendroth

Regional Experts Group for Osteoporosis in Saxony and Thuringia, Jena, Germany

 
P334 W
BONE MASS ASSESSMENT BY DIGITAL X-RAY RADIOGRAMMETRY IN SPANISH POPULATION. COMPARISON WITH DUAL X-RAY ABORPTIOMETRY AND QUANTITATIVE ULTRASOUND

C. Gómez*, L. Casado, J. C. Barredo, A. Iglesias, V. Valencia, M. Naves, J. L. Fernández, J. B. Díaz, J. B. Cannata

Bone and Mineral Research Unit, Instituto Reina Sofía de Investigación, Hospital Central de Asturias, Oviedo, Spain; Health Centre of Vallobín; Health Centre of Ventanielles; Health Centre of Castrillón, Asturias, Spain

 
P337 W
DIGITAL X-RAY RADIOGRAMMETRY ON HAND X-RAYS

N. Baadegaard*, R. Linde, O. Wendt, A. Rosholm

Pronosco A/S, Vaedbaek, Denmark

 
P340 W
AGE- AND GENDER-RELATED CHANGES IN THE HUMAN SPINE AND ILIAC CREST ASSESSED BY STATIC HISTOMORPHOMETRY

J. S. Thomsen*, E. N. Ebbesen, L. Mosekilde

Department of Cell Biology, University of Aarhus, Aarhus, Denmark

 
P343 W
BONE RESORPTION IN POSTMENOPAUSAL WOMEN WITH NORMAL AND LOW BMD ASSESSED WITH BIOCHEMICAL MARKERS SPECIFIC FOR TELOPEPTIDE DERIVED DEGRADATION PRODUCTS OF COLLAGEN TYPE I

J. Y. Reginster*, A. N. Taquet, C. Christiansen, E. Gamwell-Henriksen, O. Bruyere, J. Collette, S. Christgau

WHO Collaborating Center for Public Health Aspects of Osteoarticular Disorders; Bone and Cartilage Metabolism Unit, University of Liège, Liège, Belgium; Center for Clinical and Basic Research, Ballerup, Denmark; Osteometer BioTech, Herlev, Denmark

 
P346 W
BIOCHEMICAL MARKERS IN MENOPAUSAL WOMEN

J. Ferrer-Cañabate*, I. Tovar, P. Martinez

Servicio AA.CC. H.U. Virgen Arrixaca

 
P349 W
URINARY EXCRETION OF B, CA, MG AND P IN POSTMENOPAUSAL WOMEN WITH AND WITHOUT OSTEOPOROSIS

E. Arévalo González*, O. M. Alarcón, M. Mora, J. R. Vielma, L. Linares de M., G. Hernández de Avila

Universidad de Los Andes, Mérida, Venezuela

 
P352 W
IS FRACTURE RISK RELATED TO THE RELATIVE RATES OF BONE FORMATION VERSUS RESORPTION? A PROSPECTIVE STUDY

J. W. Davis, P. D. Ross*, W. Knowlton, H. Katagiri, R. D. Wasnich

Hawaii Osteoporosis Center, Honolulu, HI, USA; Merck & Co., Inc., Rahway, NJ, USA; Tottori University, Yonago, Japan

 
P355 W
THE EFFECT OF STORAGE AND MAILING ON STABILITY OF URINARY NTX

R. A. Hannon*, I. B. Catch, A. Price, R. Eastell

Bone Metabolism Group, Division of Clinical Sciences (NGHT), University of Sheffield, Sheffield, UK; Clinical Chemistry, Northern General Hospital, Sheffield, UK

 
P358 W
CONSIDERATIONS REGARDING SOME BIOCHEMICAL MARKERS OF BONE METABOLISM AND OF CALCIOTROPIC HORMONES IN A GROUP OF ELDERLY SUBJECTS

I. Zosin*, P. Bottermann, D. Ivan, C. Crista, D. Muresan

Clinic of Endocrinology, University of Medicine and Pharmacy, Timisoara, Romania; 2nd Medical Clinic, Medical Faculty of Technical University, Munich, Germany

 
P361 W
PREDICTION OF FRACTURE LOAD: A CHICKEN TIBIA MODEL OF IMPENDING PATHOLOGICAL FRACTURE USING ULTRASOUND DENSITOMETRY

R. S. Yang*, C. H. Lin, T. H. Huang, S. J. Lin

National Taiwan University, Taipei, Taiwan; National Taiwan Normal University, Taipei, Taiwan

 
P364 W
THE IDENTIFICATION OF FRACTURE PATIENTS AT RISK OF OSTEOPOROSIS USING ULTRASOUND AS A RISK ASSESSMENT TOOL

H. J. Veevers*, I. Stewart, D. P. Montgomery, A. Doyle

Blackpool Wyre & Fylde Community Health Service NHS Trust, Blackpool, UK; Blackpool Victoria Acute Trust, Blackpool, UK; Blackpool Primary Care Group, Blackpool, UK

 
P367 W
EUROPEAN PEDIATRIC REFERENCE DATA FOR QUANTITATIVE ULTRASOUND OF FINGER PHALANGES

R. Barkmann*, W. Rohrschneider, G. Baroncelli, R. Lorenc, R. Tormo, C-C. Glüer

Medizinische Physik, UKK Kiel, Germany; Pädiatrische Klinik der Universität Heidelberg, Germany; Department of Reproductive Medicine and Pediatrics, Pisa, Italy; Children's Mem. Health Institute, Warsaw, Poland; Hospital Materno-Infantil "Vall d'Hebron", Barcelona, Spain

 
P370 W
DIAGNOSTIC OF OSTEOPOROSIS: CUT-OFF LEVELS BASED ON CALCANEOUS ULTRASOUND WITH TWO DIFFERENT DEVICES

A. Diez-Pérez*, J. Puig, M. J. Peña, L. Mellibovsky, J. Carbonell, X. Sanz, X. Nogués

Hospital del Mar-UAB and URFOA-IMIM, Barcelona, Spain

Osteoporosis: Epidemiology

P373 W
EPIDEMIOLOGY OF OSTEOPOROSIS IN BRASIL AND THE EFFICACY OF A UNIQUE AND NATURAL DOLOMITE IN THE TREATMENT OF THE DISEASE

S. Edelstein*, H. J. R. Sanson, M. Lev-Ran, I. Otremski, A. Ornoy

Weizmann Institute of Science, Rehovot, Israel; Minervale Minerios Industriais Ltda, Sao Paulo, S.P., Brasil

 
P376 W
THE SIGNIFICANCE OF SERUM UNDERCARBOXYLATED OSTEOCALCIN LEVELS IN TYPE II DIABETIC OSTEOPOROSIS

T. Horiuchi*, T. Hosoi, T. Nakamura, J. Inoue, S. Mizuno, H. Orimo

Tokyo Metropolitan Geriatric Center; Tokyo Metropolitan Geriatric Institute

 
P379 W
CLINICAL CHARACTERISTICS AND AETIOLOGICAL FACTORS OF PRE-MENOPAUSAL OSTEOPOROSIS

P. Peris*, N. Guañabens, L. Alvarez, A. Monegal, I. Ros, M. J. Martínez de Osaba, F. Pons, J. Muñoz-Gómez

Hospital Clinic, University of Barcelona, Spain

 
P382 W
EFECTS OF THE LOW BODY MASS INDEX ON THE VERTEBRAL MINERAL DENSITY AND BONE TURNOVER IN WOMEN WITH MILD FORM OF ANOREXIA NERVOSA AND REGULAR MENSES

C. Dumitrache*, D. Grigorie, C. Barbu, E. Neacsu, M. Dumitrache

C. I. Parhon Institute of Endocrinology, Bucharest, Romania

 
P385 W
VITAMIN D STATUS IN ELDERLY WOMEN WITH HIP FRACTURE

R. Nuti*, G. Martini, R. Valenti, S. Giovani, S. Salvadori, M. G. Silvestri, A. Picchi, B. Galli, A. Spinola

Chair of internal Medicine, Metabolic Disease Unit, University of Siena, Italy

 
P388 W
BONE MINERAL DENSITY AND CONTENT IN PREMENOPAUSAL WOMEN CONSUMING A VEGAN OR OMNIVORE DIET

L. Stawasz*, B. Gale, K. Parker, B. Garzelli, A. Oberbauer, M. Van Loan

University of California, Davis, Davis, CA, USA; United States Department of Agriculture, Western Human Nutrition Research Center, Davis, CA, USA

 
P391 W
THE RELATIONSHIP OF AGE AT MENARCHE AND BONE MINERAL DENSITY

L. Qin*, J. Chen, W. Zhang, H. Ma, C. Ge, Y. Xiao

China-Japan Friendship Hospital, Beijing, China

 
P394 W
BACK PAIN AND RELATED DISABILITY BEFORE AND AFTER CLINICALLY DIAGNOSED VERTEBRAL FRACTURES

M. Nevitt*, L. Palermo, D. Thompson, D. Bauer, H. Fink, K. Stone, K. Ensrud, D. Black

University of California, San Francisco, USA; Merck Scientific Communications, Rahway, NJ, USA; University of Minnesota, Minneapolis, USA

 
P397 W
PERIPHERAL FRACTURE RATE IS REFLECTED BY BONE MINERAL DENSITY AT THE AXIAL AND PERIPHERAL SKELETON

C. Horvath*, K. Bors, S. Meszaros, J. Szucs, E. Hosszu

1st Dept.Medicine, Semmelweis University, Budapest, Hungary; Ferencvaros Osteoporosis Centre, Budapest, Hungary; 2nd Dept. Pediatrics, Semmelweis University, Budapest, Hungary

 
P400 W
THE RESULTS OF PAMUKKALE OSTEOPOROSIS STUDY IN TURKEY

Y. Sermez*, M. G. Taþkale, N. Oruç

Pamukkale University, Department of Endocrinology and Metabolism, Denizli, Turkey

 
P403 W
PATHOGENETIC ASPECTS OF DIABETIC OSTEOPENIA IN IDDM PATIENTS

A. Katushkina*, E. Kholodova, T. Mokhort

Minsk Medical Institute, Belarus

 
P406 W
OSTEOPOROSIS AND BONE METABOLISM IN PREMENOPAUSAL PATIENTS WITH CONGENITAL HIP DYSPLASIA

C. M. Bonelli*, A. Fahrleitner, D. Walter, V. Stepan, C. J. Piswanger-Sölkner, H. Dobnig, G. Leb, B. Obermayer-Pietsch

Department Internal Medicine, Karl Franzens Universität Graz,Austria

 
P409 W
IS ASTHMA RELATED TO INCREASED FRACTURE RISK IN PERIMENOPAUSAL WOMEN?

A. K. Laatikainen*, H. P. J. Kröger, R. J. Honkanen, H. O. Tukiainen, S. V. Saarikoski

Department of Respiratory Medicine, Kuopio University Hospital, Finland; Department of Surgery, Kuopio University Hospital, Finland; Research Institute of Public Health, University of Kuopio, Finland; Department of Obstetrics and Gynaecology, Kuopio University Hospital, Finland

 
P412 W
CHANGES OF GROWTH HORMONE IN PATIENTS WITH HYPERTHYROIDISM COMPLICATED BY OSTEOPOROSIS

Y. L. Zhang*, S. Q. Guo

Department of Endocrinology, Baoding The First Hospital, Hebei Province, Baoding 071000, China

 
P415 W
THE EFFECT OF HAND OSTEOARTHRITIS ON PERIPHERIC AND AXIAL BONE MINERAL DENSITY

S. Bagis*, G. Sahin, A. Bicer, O. Bolgen Cimen, S. Ozisik, C. Erdogan

Mersin University, School of Medicine, Department of Physical Medicine and Rehabilitation, Mersin, Turkey

 
P418 W
RELATIONSHIP BETWEEN LIPID PROFILE AND BONE MASS IN HEALTHY MALES

S. Adami*, V. Braga, M. Zamboni, D. Gatti, J. Bakri

Rheumatology Unit, Valeggio S/M, Italy; Geriatric Unit, Verona, Italy

 
P421 W
OSTEOPOROSIS IN MEN

G. Resmini*, P. Ballanti, E. Bonucci, A. Rubinacci

Bone Metabolic Unit, Scientific Institute H. San Raffaele, Milan, Italy; Dept. of Experimental Medicine and Pathology, "La Sapienza" University, Rome, Italy

 
P424 W
BALANCE AND POSTURAL MEASURES ARE ASSOCIATED WITH BONE MASS IN ELDERLY, COMMUNITY-DWELLING WOMEN

C. T. Lindsey, A. R. Brownbill, E. H. Mulrenan, R. W. Bohannon, J. Z. Ilich*

University of Connecticut

 
P427 W
MULTIPLE NONSPINE FRACTURES ARE ASSOCIATED WITH GREATER PHYSICAL IMPAIRMENT

J. W. Davis, P. D. Ross*, J. Chandler, W. Knowlton, R. D. Wasnich

Hawaii Osteoporosis Center, Honolulu, HI; Merck & Co., Inc., Rahway, NJ, USA

Osteoporosis: Pathophysiology

P430 W
NORMAL VALUES FOR QUANTITATIVE ULTRASONOMETRY AT DIFFERENT SKELETAL SITES (RADIUS, TIBIA) IN HEALTHY CAUCASIAN BOYS AGED 7-19 YEARS – INTERIM ANALYSIS OF 228 BOYS MEASURED

O. Bock*, M. Berndsen, T. Biedermann, A. Oldenburg, M. Schöntube, D. Felsenberg

Free University Berlin, University Hospital Benjamin Franklin, Osteoporosis Research Group, Berlin, Germany; Dept.of Rheumatology, 2nd Children's Hospital, Klinikum Buch, Berlin, Germany

 
P433 W
COMPUTED-TOMOGRAPHY BONE-DENSITY MEASUREMENTS IN NORMAL PRE- AND POST-PUBERTAL FEMALES

T. N. Hangartner*, M. E. Miller

BioMedical Imaging Laboratory, Wright State University, Dayton OH, USA; Department of Pediatrics, Wright State University, Dayton, OH, USA

 
P436 W
BONE MARKERS PROFILE DURING ADOLESCENT PREGNANCY ON CALCIUM SUPPLEMENTATION

J. A. Prada*, R. I. Sierra, R. C. Tsang, S. Guo

Children's Hospital Medical Center, Cincinnati, Ohio, USA; Wright State University, Dayton, Ohio, USA

 
P439 W
NON-INVASIVE BONE MASS MEASUREMENTS PREDICT BONE STRENGTH IN GROWING ANIMALS

M. Koo*, K. Yang, P. Begeman, M. Hammami, W. Koo

Bioengineering Center, Wayne State University, Detroit, MI, USA; Department of Pediatrics, Wayne State University, Detroit, MI, USA

 
P442 W
Withdrawn

 
P445 W
THE INFLUENCE OF HIGH ENERGETIC EXTRACORPORAL SHOCK WAVES ON BONE DENSITIY IN HUMAN CALCANEUM

L. Gerdesmeyer*, H. Rechl, T. Schrader, M. Weber, A. Heinzel

Clinic of Orthopeadic Surgery and Sportstraumtology, Technical University of Munichand, Munich, Germany; Clinic of Nuclear Medicine, Technical University of Munich, Munich, Germany

 
P448 W
STRUCTURAL COMPLEXITY OF CANCELLOUS BONE: A FRACTAL ANALYSIS

I. H. Parkinson*, N. L. Fazzalari

Division of Tissue Pathology, Institute of Medical and Veterinary Science, South Australia; Department of Pathology, Adelaide University, South Australia

 
P451 W
ANABOLIC EFFECTS OF COXARTHROSIS CONFER PROTECTION AGAINST INTRA-CAPSULAR HIP FRACTURE

G. R. Jordan*, N. Loveridge, J. Power, N. Rushton, J. Reeve

University of Cambridge, Cambridge, UK

 
P454 W
EVALUATION OF BONE MASS AND BONE QUALITY IN CHILDREN WITH ASTHMA TREATED WITH ANTI-INFLAMMATORY STEROIDS BY DXA AND QUS: PRELIMINARY RESULTS

M. Jaworski*, K. Nowacka, R. S. Lorenc

Dept. of Bioch. and Exp. Medicine, Children's Memorial Health Institute, Warsaw, Poland; Dept. of Allergology, Spec. Children's Hospital, Warsaw, Poland

 
P457 W
STUDY OF BONE MINERAL DENSITY IN PATIENTS WITH BRONCHIAL ASTHMA ON GLUCOCORTICOID THERAPY

I. Baranova*, N. Toroptsova, K. Gadjiev, N. Demin, A. Chuchalin

Pulmonology Research Institute, Moscow, Russia; Institute of Rheumatology, Moscow, Russia

 
P460 W
COMMUNITY USE OF ORAL GLUCOCORTICOSTEROIDS IN ICELAND AND PROPHYLACTIC TREATMENT FOR STEROID-INDUCED OSTEOPOROSIS IN DAILY CLINICAL PRACTICE

U. I. Juliusson, F. V. Gudjonsson, B. Gudbjornsson*

Department of Medicine, Akureyri, Iceland; Health Care Center, Akureyri, Iceland; Centre for Rheumatology Research, Reykjavik, Iceland

 
P463 W
EFFECTS OF SURGERY ON BONE MINERAL DENSITY IN OBESE PATIENTS

M. L. Fernandez-Soto*, E. Ferrandiz, M. Quesada, V. Luna, F. Leruite, A. Gonzalez, P. Mezquita, F. Escobar-Jimenez

University Hospital San Cecilio, Granada, Spain

 
P466 W
OSTEOMALACIA IN IMMIGRANTS FROM THE MIDDLE EAST

J. Feldkamp*, M. Schott, R. Fritzen, W. A. Scherbaum

Dept. of Endocrinology, Heinrich-Heine-University, Duesseldorf, Germany

 
P469 W
THE EFFECT OF CALCIUM & VITAMIN D SUPPLEMENTATION IN INDO-ASIANS SUFFERING FROM HYPOVITAMINOSIS D WITH OR WITHOUT SECONDARY HYPERPARATHYROIDISM

E. Serhan*, M. R. Holland

Department of Rheumatology, New Cross Hospital, Wolverhampton, UK; Department of Cinical Chemistry, New Cross Hospital, Wolverhampton, UK

 
P472 W
ENERGY AND NUTRIENTS INTAKE IN A GROUP OF PSYCHOLOGICAL DISABLED PEOPLE

L. Pérez Gallardo*, Y. García Pérez, J. Gil Mateo

Bioquímica y Biología Molecular, Universidad de Valladolid, Spain

 
P475 W
A COMMON FACTOR RAISES BLOOD PRESSURE AND PROTECTS AGAINST FRACTURES AMONGST MIDDLE-AGED AND ELDERLY MEN

G. Sigurdsson*, K. Siggeirsdottir, B. Y. Jonsson, B. Mogensen, H. Jonsson jr

Department of Medicine, Landspitali, University Hospital, Reykjavik, Iceland; Icelandic Heart Association, Reykjavik, Iceland; Akranes Hospital, Akranes, Iceland; Orthopaedic Department, University Hospital, Reykjavik, Iceland

 
P478 W
CAUSES OF OSTEOPOROSIS IN MEN WITH HIP FRACTURES

D. N. Edis*, B. Erbas, S. Yeung, C. Poon, P. R. Ebeling

Dept Surgery, University of Melbourne, Australia; Dept General Practice and Public Health, University of Melbourne, Australia; Dept. Diabetes and Endocrinology, University of Melbourne, Royal Melbourne Hospital, Australia

 
P481 W
DIFFERENCES OF CALCANEAL ULTRASONOMETRY BETWEEN PHYSICAL EDUCATION AND SPORT SCHOOL STUDENTS AND MEDICAL FACULTY STUDENTS

B. Durmaz*, B. Ozcaldiran

Ege University Medical Faculty, Physical Therapy and Rehabilitation Department , Turkey; Ege University, Physical Education and Sport School, Turkey

 
P484 W
EFFECT OF STEP MASTER AND NORDIC TRACK ON BIOCHEMICAL MARKERS OF BONE METABOLISM, BONE DENSITY, FITNESS, AND STRENGTH IN PREMENOPAUSAL WOMEN

M. Sinaki, J. Canvin*, P. Phillips, B. Clarke

Mayo Clinic, Rochester, MN, USA

 
P487 W
QUANTITATIVE ULTRASOUND AND OSTEOPOROSIS RISK FACTORS: EXERCISE IS INDEPENDENT OF BONE DENSITY

S. Dodin*, C. Blanchet, Y. Giguère, F. Rousseau, L. Turcot-Lemay, M. Dumont, D. Prud'homme

Unité de recherche en endocrinologie de la reproduction, Pavillon St-François D'Assise, CHUQ, Québec, Canada; Laboratoire des Sciences de l'activité physique, Division Kinésiologie, Département de médecine sociale et préventive, Faculté de médecine, Université Laval, Québec, Canada; Centre Ménopause Québec, Pavillon St-François D'Assise, CHUQ, Québec, Canada; Unité de recherche en génétique humaine et moléculaire, Pavillon St-François D'Assise, CHUQ, Québec, Canada; Département de médecine nucléaire, Pavillon St-François D'Assise, CHUQ, Québec, Canada

 
P490 W
FOREARM BONE MINERAL DENSITY IN PATIENTS WITH RHEUMATOID ARTHRITIS

J. Iwamoto*, T. Takeda, S. Ichimura

Keio University School of Medicine, Tokyo, Japan; National Defense Medical College, Saitama, Japan

 
P493 W
THE BIOLOGY OF THE SOFT CALLUS IN LONG BONE FRACTURE REPAIR

J. L. Ford*, B. E. Scammell, D. Robinson

University of Nottingham, UK

 
P496 W
DIETARY PHOSPHORUS MODULATES TRABECULAR BONE MASS AND STRENGTH IN OVARIECTOMIZED RATS

R. Masuyama*, M. Koshihara, S. Tanaka, T. Nakamura, M. Uehara, K. Suzuki

Tokyo University of Agriculture, Tokyo, Japan; University of Occupational and Environmental Health

 
P499 W
DIETARY AND OTHER DETERMINANTS OF SUDDEN-ONSET POST-MENOPAUSAL BONE GAIN AND OSTEOARTHRITIS IN THE SPINE

R. Abraham, J. Walton, A. Nicholls, J. Justice, B. Wardley-Smith, J. Reeve*

Clinical Research Centre, Northwick Park Hospital, London, UK; Department of Medicine, University of Cambridge, Cambridge, UK

 
P502 W
CHANGES IN BIOCHEMICAL MARKERS OF BONE METABOLISM IN MALE PATIENTS WITH HUMAN IMMUNODEFICIENCY VIRUS INFECTION DURING POTENT ANTIRETROVIRAL THERAPY

J. Teichmann*, U. Lange, G. Friese, T. Discher, J. Lohmeyer, H. Stracke, R. G. Bretzel

Medizinische Klinik und Poliklinik III, Klinikum der Justus-Liebig-Universität, Giessen, Germany; Medizinische Klinik und Poliklinik II, Klinikum der Justus-Liebig-Universität, Giessen, Germany

 
P505 W
EFFECT OF PUBERTY, AGEING AND GENDER ON SERUM N-TERMINAL PROPEPTIDE OF TYPE I PROCOLLAGEN (PINP) AND C-TERMINAL TELOPEPTIDE OF TYPE I COLLAGEN (S-CTX)

Y. M. Henry*, A. C. Eagleton, D. Fatayerji, R. Eastell

University of Sheffield, UK

 
P508 W
EFFECTS OF LOW DOSE METHOTREXATE ON BONE MINERAL DENSITY AND BONE TURNOVER

L. Ogunremi*, R. Wills, J. Barron, S. Patel

Osteoporosis Unit, St George's Hospital, London, UK; Dept Clinical Chemistry, St Helier Hospital, Carshalton, Surrey, UK; Dept Rheumatology, St Helier Hospital, Carshalton, Surrey, UK

 
P511 W
BREAST CANCER AND OSTEOPOROSIS - A LINK BETWEEN TWO FREQUENT DISEASES OF POSTMENOPAUSAL WOMEN

P. Hadji*, M. Kalder, K. Bock, U. S. Albert, G. Emons, K. D. Schulz

Philipps-University of Marburg, Marburg, Germany

 
P514 W
INFLUENCE OF ESTROGEN RECEPTOR GENOTYPE ON BONE MINERAL DENSITY IN CHINESE HAN WOMEN

Y. Xue*, D. Li

Department of Biochemistry, Beijing Ji Shui Tan Hospital, Beijing, P.R. China

 
P517 W
CERIVASTATIN INCREASES SOME CANCELLOUS BONE FORMATION INDICES IN OVX RATS

S. C. Miller*, B. M. Bowman, C. Bagi

University of Utah, Salt Lake City, USA; Bayer Pharmaceutical Division, West Haven, CT, USA

 
P520 W
THREE-DIMENSIONAL MORPHOMETRIC ANALYSIS OF THREE DIFFERENT SKELETAL SITES IN OVARIECTOMIZED RAT MODEL OF OSTEOPOROSIS: EFFECT OF PREVENTATIVE ADMINISTRATION OF ALFACALCIDOL AND ALENDRONATE

A. Nishida*, M. Ito, K. Hayashi, A. Shiraishi, S. Higashi, Y. Uchida

Department of Radiology, Nagasaki University, Japan; Product Research Laboratory, Chugai Pharmaceutical Co, Ltd

 
P523 W
ESTABLISHMENT OF AN OSTEOPOROTIC GOAT ANIMAL MODEL

W. S. Siu*, N. M. Cheung, P. P. Y. Lui, D. H. K. Chow, A. James, L. Qin, K. S. Leung

Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong; The Rehabilitation Engineering Center, The Hong Kong Polytechnics University; Laboratory Animal Services Center, The Chinese University of Hong Kong

 
P526 W
BOTH HIGH DIET CALCIUM AND MECHANICAL STIMULATION ARE REQUIRED TO PROTECT AGAINST OVARIECTOMY-INDUCED BONE LOSS IN THE RAT

H. A. Morris*, A. J. Moore, P. D. O'Loughlin, B. Jansen, R. Larik

Institute of Medical and Veterinary Science, Adelaide, South Australia, 5000

Osteoporosis: Treatment

P529 W
THE EFECT OF FLUORIDE ON MINERAL FORMATION IN NOVEL HYDROGEL MATRICES OF POLY (VINYLALCOHOL)

J. P. Cassella*, I. Ahmed, S. Elliott

Division of Biological Sciences; Division of Environmental Sciences

 
P532 W
PRELIMINARY OUTCOMES OF THE FIRST 311 CONSECUTIVE KYPHOPLASTIES FOR THE FIXATION OF PAINFUL OSTEOPOROTIC VERTEBRAL COMPRESSION FRACTURES

J. M. Lane, F. P. Girardi*, S. N. Khan, F. P. Cammisa, P. Philips, H. Yuan, S. Garfin, I. H. Lieberman, H. K. Parvataneni

Hospital for Special Surgery, Weill Medical College of Cornell University; University of Chicago; SUNY; UCSD; Cleveland Clinic

 
P535 W
EFFECTS OF HMG-COA REDUCTASE INHIBITORS, STATINS, ON BONE LOSS: A PROSPECTIVE POPULATION-BASED COHORT STUDY IN EARLY POSTMENOPAUSAL WOMEN

J. Sirola*, R. Honkanen, H. Kröger, J. Jurvelin, P. Mäenpää, S. Saarikoski

University of Kuopio, Kuopio, Finland; Kuopio University Hospital, Department of Surgery, Kuopio, Finland; Kuopio University Hospital, Dpt Nuclear Medicine & Clinical Physiology, Kuopio, Finland; Kuopio University Hospital, Department of Obstetrics and Gynaecology, Kuopio, Finland

 
P538 W
MILK BASIC PROTEIN (MBP) PROMOTES BONE FORMATION AND SUPPRESSES BONE RESORPTION IN VIVO

A. Itabashi*, Y. Takada, Y. Toba, Y. Matsuoka, S. Aoe, H. Kawakami, K. Nemoto, M. Kumegawa

Clin Lab Med, Saitama Medical School, Saitama, Japan; Nutr Sci Lab, Snow Brand Milk Co,, Saitama, Japan; Oral Anatomy, Meikai University of Dentistry, Saitama, Japan

 
P541 W
ALENDRONATE TREATMENT OF PATIENTS WITH POSTMENOPAUSAL OSTEOPOROSIS AND IMPAIRED FASTING GLUCOSE

M. Cokolic*, R. Hren

Teaching Hospital Maribor, Maribor, Slovenia; University of Ljubljana, Ljubljana, Slovenia

 
P544 W
INTRAVENOUS PAMIDRONATE TREATMENT IN PATIENTS' HOMES

K. R. H. Adams*, K. Turner

Royal Bolton Hospital UK

 
P547 W
RAPID AND SUSTAINED HIP FRACTURE RISK REDUCTION WITH RISEDRONATE IN ELDERLY WOMEN WITH OSTEOPOROSIS

C. Cooper*, J. Y. Reginster, M. McClung, N. L. Zorich, Z. Li

University of Southampton, Southampton, UK; University of Liege, Liege, Belgium; Oregon Osteoporosis Center, Portland, OR, USA; Procter & Gamble Pharmaceuticals, Mason, OH, USA

 
P550 W
BONE MINERAL DENSITY CHANGES IN THE FIRST TWO YEARS FOLLOWING DISCONTINUATION OF ALENDRONATE

J. D. Gay*, D. S. Ooi

Ottawa Hospital Civic Campus, Ottawa, Canada

 
P553 W
ZOLEDRONIC ACID, A POTENT NEW BISPHOSPHONATE, REVERSES MECHANICAL HYPERALGESIA IN TWO RAT MODELS OF CHRONIC INFLAMMATORY AND NEUROPATHIC PAIN

A. Fox, S. Patel, K. McNair, A. Kesingland, L. Urban, J. R. Green*

Novartis Institute for Medical Sciences, London, UK; Novartis Pharma Research, Basel, Switzerland

 
P556 W
ONE YEAR STUDY OF ALENDRONATE EFFECTS ON VERTEBRAL MINERAL DENSITY AND BONE TURNOVER IN WOMEN WITH MILD TYPE I OSTEOGENESIS IMPERFECTA

D. Grigorie*, C. Barbu, E. Neacsu, M. Dumitrache, M. Grigorie, C. Dumitrache

C. I. Parhon Institute of Endocrinology, Bucharest, Romania; Ana Aslan Institute of Geriatrics and Gerontology, Bucharest, Romania

 
P559 W
RISEDRONATE SIGNIFICANTLY REDUCES THE RISK OF NEW VERTEBRAL FRACTURES, IN WOMEN IRRESPECTIVE OF THE NUMBER OF PREVALENT VERTEBRAL FRACTURES IN JUST ONE YEAR

R. Eastell*, J. Compston, C. Roux, N. Alsayed, I. Barton

University of Sheffield, Sheffield, UK; University of Cambridge, Cambridge, UK; Rene Descartes University, Paris, France; Procter & Gamble Pharmaceuticals, Geneva, Switzerland; Procter & Gamble Pharmaceuticals, Staines, UK

 
P562 W
ALENDRONATE VS. CALCITONIN: 2-YEAR TREATMENT OF OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN

C. J. Rosen*, T. J. Schnitzer, M. McClung, P. D. Miller, L. Wang, L. K. Vanaman, J. Yates, M. E. Melton, J. Palmisano

St. Joseph Hospital, Bangor, ME, USA; Northwestern University, Chicago, IL, USA; Oregon Osteoporosis Center, Portland, OR, USA; Colorado Center for Bone Research, Lakewood, CO, USA; Merck & Co., Inc., West Point, PA, USA

 
P565 W
ALENDRONATE IS MUCH MORE EFFECTIVE THAN CALCITONIN AND ALFACALCIDOL FOR PREVENTING NONVERTEBRAL FRACTURES

K. Aoyagi*, M. Shiraki, M. Ito, T. Nakamura

Public Health, Nagasaki University; Research Institute and Practice for Involutional Diseases; Radiology, Nagasaki University; Orthopedic Surgery, University of Occupational and Environmental Health

 
P568 W
RISEDRONATE REDUCES THE RISK OF NEW VERTEBRAL FRACTURES IN 1 YEAR IN POSTMENOPAUSAL WOMEN ON CORTICOSTEROID THERAPY

J. P. Devogelaer*, D. Hosking, S. Wallach, D. J. Valent

Louvain Catholic University, Brussels, Belgium; Nottingham City Hospital, Nottingham, UK; Hospital for Joint Diseases, New York, NY, USA; Procter & Gamble Pharmaceuticals, Geneva, Switzerland

 
P571 W
A ONE-YEAR RANDOMIZED TRIAL OF ETIDRONATE AND VITAMIN K IN COMBINATION WITH VITAMIN D IN POSTMENOPAUSAL PATIENTS WITH RHEUMATOID ARTHRITIS

J. H. Hashimoto*, T. T. Tomita, H. O. Owaki, K. T. Tsuyama, T. O. Ochi, H. Y. Yoshikawa

Dept. of Orthopedic Surg., Osaka University Medical School, Osaka, Japan; Dept. of Orthopedic Surg., Osaka Kousei-Nenkin Hospital, Osaka, Japan

 
P574 W
ALENDRONATE VS INTRANASAL CALCITONIN FOR TREATMENT OF OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN: 2 YEAR RESULTS

R. W. Downs*, N. H. Bell, B. Walsh, M. P. Ettinger, B. Mako, M. E. Smith, L. Wang, J. Yates, M. E. Melton, J. Palmisano

Medical College of Virginia, Richmond, VA, USA; University of South Carolina Research Service VMAC, Chareston, SC, USA; Brigham & Women's Hospital, Boston, MA, USA; Radient Research, Stuart, FL, USA; Merck & Co., Inc., West Point, PA, USA

 
P577 W
SUSTAINED FRACTURE BENEFIT WITH FIVE YEARS OF RISEDRONATE IN POSTMENOPAUSAL WOMEN

D. Hosking*, O. D. Sorensen, H. Mulder, S. Adami, S. Pack, D. Wenderoth, J. Y. Reginster

Nottingham City Hospital, Nottingham, UK; Hvidovre Universitetshospital, Hvidovre, Denmark; Research Center Good Clinical Practice, Rotterdam, The Netherlands; Clinicizzato di Valeggio, Valeggio, Italy; Procter & Gamble Pharmaceuticals, Staines, UK; University of Liège, Liège, Belgium

 
P580 W
DEXA AND PQCT CHANGES AFTER A CONTINUOUS INTRANASAL CALCITONIN TREATMENT IN WOMEN WITH POST MENOPAUSAL OSTEOPOROSIS

E. Kataxaki*, G. Skarantavos, I. Koulouris, G. Trovas, G. Raptou, M. Katsiri, M. Tsipra, A. Galanos, G. P. Lyritis

Laboratory for the Research of the Musculoskeletal System

 
P583 W
Withdrawn

 
P586 W
SUBSTANTIAL BENEFICIAL EFFECTS OF CALCIUM SUPPLEMENTATION ON SERUM LIPIDS IN NORMAL POSTMENOPAUSAL WOMEN

I. R. R. Reid*, B. Mason, A. Horne, R. Ames, J. Clearwater, F. Wu, M. C. Evans, G. Gamble

University of Auckland, Auckland, New Zealand

 
P589 W
FERMENTED SOYBEANS MAY ACCELERATE PREMENOPAUSAL BONE GAIN AND DECELERATE POSTMENOPAUSAL BONE LOSS IN HEALTHY JAPANESE POPULATION - JPOS COHORT STUDY

M. Iki*, A. Morita, Y. Ikeda, H. Aihara, A. Yura, S. Kagamimori, Y. Kagawa, T. Matsuzaki, H. Yoneshima, F. Marumo

Kinki University School of Medicine, Osaka-Sayama, Japan; Toyama Medical and Pharmaceutical University, Toyama, Japan; Kagawa Nutrition University, Tokyo, Japan; Institute of Comprehensive Community Health Care, Tokyo, Japan; Kasukabe-Shuuwa Hospital, Kasukabe, Japan; Tokyo Medical and Dental University, Tokyo, Japan

 
P592 W
DOES HORMONE REPLACEMENT THERAPY PREVENT NON VERTEBRAL FRACTURES: A REVIEW OF RANDOMISED TRIALS AND META-ANALYSIS

D. J. Torgerson*, S. E. M. Bell-Syer

University of York, York, UK

 
P595 W
DOES SMOKING INFLUENCE THE EFFICACY OF RALOXIFENE IN POSTMENOPAUSAL OSTEOPOROTIC WOMEN? RESULTS FROM THE MORE TRIAL

R. D. Chapurlat*, D. C. Bauer, S. Ewing, S. R. Cummings

University of California, San Francisco, USA

 
P598 W
DOSE-RELATED DECREASES IN BONE BIOMARKERS DUE TO NORETHINDRONE ACETATE IN POSTMENOPAUSAL WOMEN TREATED WITH ETHINYL ESTRADIOL

J. A. Simon*, J. C. Gallagher, B. Drinkwater, J. P. Symons

George Washington University School of Medicine, Washington, DC, USA; Creighton University Medical Center, Omaha, Nebraska, USA; Pacific Medical Center, Seattle, Washington, USA; Pfizer Global Research and Development, Ann Arbor, Michigan, USA

 
P601 W
COMPARISON OF FC1271A, A NOVEL SERM, AND RALOXIFENE IN POSTMENOPAUSAL WOMEN: A 12-WEEK CLINICAL PHASE II STUDY

R. U. Erkkola*, M. DeGregorio, K. Halonen, Kangas, Lammintausta, Vihko, J. Heikkinen, S. Kivinen, S. Saarikoski, R. Tuimala, Vihtamäki, M. Tuppurainen, S. Voipio, O. Ylikorkala

Turku University Central Hospital, FIN-20520 Turku; University of California, Davis, Sacramento, CA, USA; Hormos Medical Ltd, FIN-20520 Turku; Oulu Deaconess Institute, FIN-90100 Oulu; Kanta-Häme Central Hospital, FIN-13530 Hämeenlinna

 
P604 W
TAI CHI EXERCISE RETARDS RATE OF BONE LOSS IN POSTMENOPAUSAL WOMEN

L. Qin*, K. M. Chan, S. K. Au, W. Y. Choy, M. C. Lau, J. Woo, K. M. Lee, M. A. Dambacher

Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China; Department of Community and Family Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China; Department of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China; LeeHysan Clinical Research Laboratory, The Chinese University of Hong Kong, Hong Kong SAR, PR China; Orthopädische Universitäsklinik Balgrist, Zürich, Switzerland

 
P607 W
COLCHICINE FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS

D. Schapira*, A. Kabala, R. Coleman

Dept Rheumatology, Rambam Medical Center, Haifa, Israel; Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel

 
P610 W
COMPLIANCE IN ANTIOSTEOPOROTIC TREATMENTS

J. Blanch*, M. Coll, J. M. Pujol, M. Ciria, L. Perez-Edo, P. Benito, J. Carbonell

Rheumatology Division, Hospitals Universitaris del Mar i de l'Esperança, Barcelona, Spain

 
P613 W
UTILITY OF MEASUREMENT OF URINARY PYRIDINOLINE AND DEOXYPYRIDINOLINE FOR MONITORING EFFECTS OF TREATMENT WITH ESTROGEN AND ALFACALCIDOL IN WOMEN WITH OSTEOPOROSIS

Z. Zhan*, I. Yamanoto, R. Morita, H. Miura

Xiao Xi Tian No.262 Hospital Beijing, China; Department of Radiology, Shiga University of Medical Science, Otsu 520-21, Japan.; Hikone Research Laboratories, Maruho Co. Ltd., Shiga 522-02, Japan

 
P616 W
ANTI-RESORPTIVE TREATMENT - A MODEL TO GAIN INSIGHT AND PREDICT LONG TERM BONE GAIN

J. C. van der Linden*, J. A. N. Verhaar, H. Weinans

Erasmus University Rotterdam, Rotterdam, The Netherlands

 
P619 W
IMPACT OF AN EDUCATIONAL PROGRAM CONSISTING OF PERIPHERAL DUAL X-RAY ABSORPTIOMETRY (PDXA) SCREENING FOLLOWED BY A LECTURE

S. Levis*, P. Lassanske, N. Dgetluck

University of Miami School of Medicine, GRECC/VA Medical Center, State of Florida Teaching Nursing Home at Miami Jewish Home & Hospital for the Aged, Miami, FL, USA; Elder Floridians Foundation, Tallahassee, FL, USA; Martin Memorial Health Systems, Stuart, FL, USA

 
P622 W
DEVELOPMENT OF A PREDICTIVE MODEL AND A RISK ASSESMENT INSTRUMENT TO FACILITATE DIAGNOSIS OF LOW BONE MASS IN POSTMENOPAUSAL WOMEN

W. Bensedrine*, T. Chevallier, M. C. Micheletti, B. Gelas, J. Y. Reginster

Department of Epidemiology and Public Health, University of Liège, Belgium; Department of Biostatistic Epidemiology and Clinical Research, University of Montpellier, France; Medical Department, Theramex Laboratory, Monaco; Georgetown University Medical Center - Washington DC, USA

 
P625 W
HISTOMORPHOMETRY AND MICROSTRUCTURE OF ILIAC TRABECULAR BONE IN OSTEOPOROSIS ON INTERMITTENT SUBCUTANEOUS ADMINISTRATION OF HUMAN PTH (1-34)

K. Nakatsuka*, H. Naka, H. Kawakami, K. Kitatani, T. Miki, Y. Nishizawa, H. Morii

Osaka City University, Osaka, Japan; Aino Gakuin College, Ibaraki, Japan

 
P628 W
THE EFFECTS OF TREATMENT INTERVENTIONS ON HEALTH RELATED QUALITY OF LIFE (HRQL) IN POST-MENOPAUSAL WOMEN REGISTERED IN THE CANADIAN DATABASE OF OSTEOPOROSIS AND OSTEOPENIA (CANDOO) PATIENTS

G. Ioannidis*, J. D. Adachi, A. Petrie, R. J. Sebaldt, A. Papaioannou, W. P. Olszynski, D. A. Hanley, C. H. Goldsmith

McMaster University, Hamilton, Ontario, Canada; University of Saskatchewan, Saskatoon, Saskatchewan, Canada; University of Calgary, Calgary, Alberta, Canada

 
P631 W
REDUCTION OF PAIN AND IMPROVEMENT OF QUALITY OF LIFE IN OSTEOPOROTIC PATIENTS UNDER TREATMENT WITH INTRANASALLY ADMINISTERED SALMON CALCITONIN

C. Ràfols*, I. Serra, R. DeCastellar, Acknowledgements to dr. Díez Pérez

ICN Ibérica S.A., Corbera de LLobregat (Barcelona), Spain; Biométrica (CRO), Barcelona, Spain; Manager of Infectious and Medical Service, Hospital de Mar, Barcelona, Spain

 
P634 W
EFFECT OF ZONISAMIDE, AN ANTIEPILEPTIC AGENT, ALONE AND IN COMBINATION WITH ALFACALCIDOL ON THE CONCENTRATIONS OF VITAMIN K ANALOGUES IN THE BONE IN GROWING RATS

A. Takahashi*, K. Onodera, H. Wakabayashi, T. Saito, H. Shinoda, H. Mayanagi

Division of Pediatric Dentistry, Department of Lifelong Oral Health Sciences, Tohoku University Graduate School of Dentistry, Sendai, Japan; Department of Dental Pharmacology, Okayama University Dental School, Okayama, Japan; Department of Biophysical Chemistry, Niigata College of Pharmacy, Niigata, Japan; Clinic of Dentistry for the disabled, Tohoku University School of Dentistry, Sendai, Japan; Division of Pharmacology, Department of Oral Biology, Tohoku University Graduate School of Dentistry, Sendai, Japan

 
P637 W
ALPHACALCIDOL IN OSTEOPOROSIS PREVENTION IN POSTMENOPAUSAL WOMEN

O. A. Nikitinskaya*, L. I. Benevolenskaya

Institute of Rheumatology, Moscow, Russia

 
P640 W
GP’S KNOWLEDGE OF CALCIUM AND VITAMIN D PREPARATIONS FOR FRACTURE PREVENTION: COMPARISON BETWEEN RESEARCH PARTICIPANTS AND CONTROLS

R. J. Barr*, A. Stewart, B. Mcdonagh, D. M. Reid

Dept. Medicine & Therapeutics, University of Aberdeen, Aberdeen, UK; Strakan Ltd, Galashiels, UK

Vitamin D

P643 W
HYPOVITAMINOSIS 1,25(OH)₂ D₃ IN PATIENTS SUFFERING FROM CHRONIC DISORDERS

J. Payer*, Z. Killinger, J. Rovenský, H. Kratochvilová, P. Ondrejka

1st Department Internal Medicine, University Hospital, Comenius University, Bratislava, Slovakia; The Research Institute of Rheumatic Diseases, Piest'any, Slovakia; The Ministry of Inferior Hospital, Bratislava, Slovakia

 
P646 W
BONE CELL REGULATION OF VITAMIN D METABOLISM

P. H. Anderson*, S. Iida, A. J. Moore, B. K. May, M. Cochran, H. A. Morris

Institute of Medical and Veterinary Science, Adelaide, Australia; Department of Physiology, Adelaide University, Adelaide, Australia.; Department of Biochemistry, Adelaide University, Adelaide, Australia

 
P649 W
INFLUENCE OF DONOR AGE AND SKELETAL SITE OF ORIGIN ON VDR MRNA EXPRESSION AND PROTEIN LEVELS AND IN RESPONSE TO 1,25(OH)₂D₃ IN HUMAN OSTEOBLASTIC CELLS

M. Garcia*, P. Martinez, I. Del Valle, L. Gomez, J. L. Castrillo, P. Esbrit, M. E. Martinez

Biochemistry Division La Paz Hospital; Molecular Biological Center (CBM); Bone and Mineral Metabolism Laboratory (Fundacion Jimenez Diaz)

 
P652 W
VITAMIN A ANTAGONIZES CALCIUM RESPONSE TO VITAMIN D IN MAN

S. Johansson*, H. Melhus

Uppsala University, Uppsala, Sweden

 
P655 W
CALCITRIOL INCREASES BONE TURNOVER BUT NOT MINERAL DENSITY IN THE STREPTOZOTOCIN-INDUCED DIABETIC RATS

J. Del Pino-Montes*, G. E. Benito, M. P. Fernández-Salazar, M. Martín, E. Martín, M. J. García-Rodriguez, M. Fernández-Puente, J. R. García-Talavera, J. J. Calvo

U. Metabolismo óseo, Hospital Universitario, Salamanca, Spain; Dept. Fisiología y Farmacología, Universidad de Salamanca, Spain; S.Medicina Nuclear, Hospital Universitario, Salamanca, Spain

Late Posters (unclassified, and not subjected to full review by the Scientific Program Committees)

P658 W
HIGH BONE TURNOVER BUT NORMAL BONE DENSITY IN WOMEN WITH SCHIZOPHRENIA

N. Bergemann, B. Auler, P. Parzer, F. Resch, C. Mundt,
M. J. Seibel

Department of Psychiatry, Department of Medicine, University of Heidelberg, Germany

 
P661 W
THE PREVENTION AND TREATMENT OF TONIFYING ESSENCE OF THE KIDNEY RECIPE FOR THE RAT OSTEOPOROSIS

Li En*, Liu Sucai, Kong Dejuan, Zhi Huiying, Yang Xuehui, Liu Hedi

Institution of Traditional Chinese and Western Medicine Basic Theory, HeBei Medical University, Shijiazhuang, P. R. China

 
P664 W

HYPOXIA IS A MAJOR STIMULATOR OF OSTEOCLASTIC BONE RESORPTION

T. R. Arnett*, D. C. Gibbons, A. Hoebertz, M. Rosendaal, S. Meghji

Department of Anatomy and Developmental Biology

Eastman Dental Institute, University College London, London, UK

P667 W
BODY COMPOSITION AND TOTAL SKELETON BONE MINERAL DENSITY IN WOMEN WITH HIP FRACTURE

C. Gómez Acotto*, E. Vega, M. Belotti, D. González, C. A. Mautalen

Sección Osteopatias Medicas, Hospital de Clínicas José de San Martín, Universidad Nacional Buenos Aires, Argentina

 
P670 W

RALOXIFEN (RLX): BENEFICIAL EFFECTS ON BONE MASS IN POSTMENOPAUSAL WOMEN - 2 YEARS FOLLOW-UP

J. J. Scali*, G. Castelli, S. Visentini, J. Salomón, P. Bárcena, E. Morales, G. Lancioni, R. Bolton, D. Sevilla

Unidad de Reumatología, Hospital Durand, Sede Coordinación Comisión Asesora de Reumatología, Secretaría de Salud, GCBA, Buenos Aires, Argentina

P673 W

OSTEOBLASTS: A NEW ROLE FUNCTION

C. Reyes-Botella*, E. Perez, M. F. Valecillo-Capilla, C. Ruiz

Departamento de Estomatología, Facultad de Odontología; Departamento de Enfermería, Escuela Universitaria Ciencias de la Salud, Universidad de Granada

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