IBMS/ECTS 2001 - PROGRAM and ABSTRACTS

SKELETAL GROWTH AND DEVELOPMENT

Saturday, June 9, 2001
14:00 - 15:00 Auditorium

IN14

The Genetic Basis of Normal and Abnormal Cranofacial Development

Irma Thesleff (Helsinki/Finland)

IN15

Functions of Fos Proteins in Bone Cell Differentiation

Erwin F. Wagner (Vienna/Austria)

[Saturday at a Glance] [Contents page]

ORAL PRESENTATIONS 7a

SKELETAL GROWTH AND DEVELOPMENT

Chairs: Pierre J. Marie (Paris/France),
Francis H. Glorieux (Montréal, Quebec/Canada)

The abstract text of oral presentations (prefix OR) can be found in the Abstracts section.

15:00 OR53

AN EXCESSIVE ACTIVATION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) INHIBITS PROLIFERATION OF CHONDROCYTES IN FGFR3-RELATED SKELETAL DISORDERS

Y. Yamanaka*, H. Tanaka, M. Koike, R. Nishimura, Y. Seino

Okayama University, Okayama, Japan; Osaka University, Osaka, Japan

15:12 OR54

BIGLYCAN AND FIBROMODULIN DOUBLE KNOCKOUT MICE EXHIBIT GAIT IMPAIRMENT AND DEVELOP ECTOPIC SESAMOID BONES AND PREMATURE OSTEOARTHRITIS IN THEIR JOINTS

L. Ameye*, D. Aria, G. Miller, X-D. Chen, P. Gehron Robey, S. Chakravarti, A. Oldberg, T. Xu, M. F. Young

CSDB, NIDCR, NIH, Bethesda, USA; Veterinary Resources Program, NIH, Bethesda, USA; Dept. of Medecine, John Hopkins University, Baltimore, USA; Dept of Cell and Molecular Biology, University of Lund, Lund, USA

15:24 OR55

LEPTIN AS A SKELETAL GROWTH FACTOR

G. Maor*, M. Ben-Eliezer, Y. Segev, M. Phillip

Technion, Haifa, Israel; Schneider Children's Medical Center, Petach Tikva, Israel.; Ben-Gurion University of the Negev, Beer-Sheva, Israel

15:36 OR56

SIGNALING VIA THE PTH/PTHrP RECEPTOR NEGATIVELY REGULATES THE FORMATION OF HEMATOPOIETIC MARROW

P. Bianco*, S. A. Kuznetsov, M. Riminucci, N. Ziran, L. Calvi, H. M. Kronenberg, P. G. Robey, E. Schipani

Universita "La Sapienza", Rome, Italy; CSDB, NIDCR, NIH, Bethesda, MD, USA; Universita dell'Aquila, L'Aquila, Italy; Endocrine Unit, Massachuesetts General Hospital, Harvard Medical School, Boston, MA, USA

15:48 OR57

DEVELOPMENT AND CHARACTERIZATION OF COL1A1-CRE TRANSGENIC MICE FOR OSTEOBLAST-DIRECTED GENOMIC RECOMBINATION

H. W. Woitge*, I. Kalajzic, M. S. Kronenberg, S. H. Clark, G. Gronowicz, A. C. Lichtler, B. E. Kream

Department of Medicine I, University of Heidelberg, Heidelberg, Germany; Department of Medicine, University of Connecticut Health Center, Farmington, USA; Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, USA; Department of Orthopedic Surgery, University of Connecticut Health Center, Farmington, USA

16:00 OR58

INCREASED BONE MASS IN MEGAKARYOCYTE DEFICIENT MICE WITH A TARGETED GENE DELETION OF THE THROMBOPOIETIN RECEPTOR

M. J. Perry*, R. L. Gibson, J. H. Tobias

University of Bristol, Bristol, UK

16:12 OR59

CAMURATI-ENGELMANN DISEASE IS CAUSED BY MUTATIONS IN THE TGFB1 GENE

K. Janssens*, R. Gershoni-Baruch, N. Guañabens, N. Migone, S. H. Ralston, H. MacPherson, M. Bonduelle, W. Lissens, L. Van Maldergem, F. Vanhoenacker, L. Verbruggen, W. Van Hul

Dept. of Medical Genetics, University of Antwerp, Antwerp, Belgium; Institute of Human Genetics, Rambam Medical Center, Haifa, Israel; Dept. of Rheumatology, Hospital Clínic., Barcelona, Spain; Dept. of Genetics, Biology and Biochemistry, University of Torino, Torino, Italy; Dept. of Medicine and Therapeutics, University of Aberdeen Medical School, Aberdeen, UK; Dept. of Medical Genetics, University Hospital of Brussels, Belgium; Center of Human Genetics, Institute of Pathology and Genetics, Loverval, Belgium; Dept. of Radiology, University Hospital of Antwerp, Belgium; Dept. of Rheumatology, University Hospital of Brussels, Belgium

16:24 OR60

RETINOIC ACID REGULATES OSTEOCLAST AND CHONDROCYTE DIFFERENTIATION IN DEER ANTLERS WHICH EXPRESS RETINOIC ACID RECEPTORS IN VIVO

S. P. Allen*, M. Maden, J. S. Price

University College, London, UK; Kings College, London, UK

16:36 OR61

IMPROVED BONE STRENGTH IN LOW BONE DENSITY C57BL/6J MICE CARRYING DONATED QTLS FROM C3H/HEJ MICE

C. H. Turner*, Q. Sun, M. L. Bouxsein, C. J. Rosen, L. R. Donahue, K. L. Shultz, W. G. Beamer

Indiana University, Indianapolis, USA; Beth Israel/ Deaconess Medical Center, Boston, USA; The Jackson Laboratory, Bar Harbor, USA

16:48 OR62

POTENTAL ROLES FOR AP-1/INTERLEUKIN-11 PATHWAYS IN MECHANICAL STRESS-INDUCED BONE FORMATION

S. Kido, D. Inoue*, E. Tohjima, T. Matsumoto

Tokushima University, Tokushima, Japan

[Saturday at a Glance]  [Contents page]