IBMS/ECTS 2001 - PROGRAM and ABSTRACTS

POSTER SESSION 3

Saturday, June 9, 2001
12:30 - 14:00

 

The abstract text of poster presentations (prefix P) can be found in the Abstracts section. Click on the Abstract number.

Posters relating to the Friday and Saturday Short Communication sessions will also be attended during this period.

Bone, Cartilage and Connective Tissue Matrix

P3 S
COMPARISON OF QUANTITATIVE ULTRASOUND PARAMETERS OF THE OS CALCIS BETWEEN THE RIGHT AND THE LEFT FOOT IN CHILDREN AND ADOLESCENTS

K. Wuensche*, B. Wuensche, H. Faehnrich, S. Vogt, W. A. Kaiser

Institute of Radiology, University Jena, Germany; Clinic of Orthopaedics, University Jena, Germany

 
P6 S
ATREMATE BRACHIOPODS: A SERENDIPITOUS MODEL FOR BONE MINERAL STUDIES OR AN EVOLUTIONARY BIOLOGICAL CURIOSITY?

J. P. Cassella*, D. I. Walton, N. Garrington

Division of Biological Sciences, Derby University, Derby, UK; Division of Earth Sciences, Derby University, Derby UK; Department of Chemistry, DeMontfort University, Leicester, UK

 
P9 S
CHARACTERIZATION OF SPECIFIC ANTIBODIES FOR FISH OSTEOCALCIN AND ITS USEFULNESS TO INVESTIGATE OSTEOCALCIN TISSUE DISTRIBUTION IN LOWER VERTEBRATES

D. C. Simes*, J. P. Pinto, P. J. Gavaia, M. L. Cancela

CCMAR, Universidade do Algarve, Campus de Gambelas, 8000 Faro, Portugal

 
P12 S
A NOVEL SPONTANEOUSLY DIFFERENTIATING CHONDROBLASTIC TISSUE CULTURE - A MODEL FOR IN VITRO ENDOCHONDRAL OSSIFICATION SYSTEM

G. Maor

Faculty of Anatomy, Technioin, Haifa, Israel

 
P15 S
ANALYSIS OF GENES REGULATED BY CTGF/HCS24 IN LIGAMENT CELLS FROM PATIENTS WITH OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT

K. Akaishi*, K. Furukawa, Y. Yamamoto, K. Ueyama, M. Tannno, S. Motomura, S. Harata

Hirosaki University, Hirosaki City, Japan

 
P18 S
COMPARATIVE HISTOMORPHOMETRIC AND SEMIQUANTITATIVE ANALYSIS OF THE BONE INGROWTH INTO DIFFERENT IMPLANTS IN GOETTINGER MINIPIGS

A. Richter*, F. Traub, M. Kratz, J. Orth

Department of Orthopaedic, Philipps University Marburg, Germany; Department of Orthopaedic, Stadtkrankenhaus, Worms, Germany

 
P21 S
GENDER-RELATED DIFFERENCES IN BONE AND MUSCLE DEVELOPMENT EVOLVING AT PUBERTY

J. A. Gasser*, D. Ellison

Novartis Pharma AG, Basel, CH; University of Bristol, Bristol, UK

 
P24 S
EFFECTS OF INCADRONATE (YM175) ON TYPE-2 COLLAGEN-INDUCED ARTHRITIS IN DA RATS

T. Iwai*, S. Yamamoto, H. Kanoh, S. Fukushima, Y. Okada, K. Takahashi

Pharmacology Laboratories, Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co. Ltd., Japan

 
P27 S
PENTADECAPEPTIDE BPC-157 AND RAT TEMPOROMANDIBULAR JOINT OSTEOARTHROSIS

N. Kokic*, P. Sikiric, S. Seiwerth, N. Stambuk, D. Perovic, G. Aralica, P. Konjevoda, M. Kolombo, J. Grgurevic, M. Staresinic

Department of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb, Croatia; Departments of Pharmacology, Pathology, Otolaryngology and Surgery, School of Medicine, University of Zagreb, Zagreb, Croatia

 
P30 S
DO THE OSTEOCYTES IN BONE ATTACH TO THEIR SURROUNDING CANALICULI AND LACUNA?

H. Kamioka*, T. Honjo, T. Takano-Yamamoto

Okayama University Dental School

 
P33 S
WEAR DEBRIS MEDIATED OSTEOLYSIS IN A RAT FEMORAL HEAD IMPLANT MODEL: WHEN DOES THIS PROCESS BEGIN

D. Fuchs*, P. Shenzer, E. Sabo, D. G. Mendes, D. Lewinson

Center of Implant Surgery Bnai Zion Medical Center, Haifa; Department of Pathology Carmel Medical Center, Haifa; Department of Anatomy and Cell Biology, Bruce Rappaport

 
P36 S
INCREASED TYPE III COLLAGEN IN THE MINERALIZED COLLAGEN FRACTION OF TRABECULAR BONE IN OSTEOARTHRITIS

S. J. Brown*, H. A. Eriksen, M. W. J. Davie, J. Risteli, C. A. Sharp

Charles Salt Research Centre, Oswestry, UK; Chester Centre for Stress Research, Chester, UK; Department of Clinical Chemistry, University of Oulu, Oulu, Finland

 
P39 S
EXPRESSION OF BMPS IN ADULT HUMAN OSTEOPHYTE TISSUE

S. Zoricic*, I. Maric, V. Santic, D. Bobinac, S. Vukicevic

Department of Anatomy, University of Rijeka, Rijeka, Croatia; Orthopedic Clinic Lovran, Lovran, Croatia; Department of Anatomy, University of Zagreb, Zagreb, Croatia

 
P42 S
Withdrawn

 
(P45 transferred to the Thursday poster session)

 
P48 S
BMP RESPONSIVENESS IN HUMAN MARROW STROMAL CELLS

D. L. Diefenderfer*, G. Grasso-Knight, P. S. Leboy

University of Pennsylvania, Philadelphia, USA

 
P51 S
BONE MORPHOGENETIC PROTEINS (BMPS) AND ITS RECEPTORS (BMPR) ARE EXPRESSED BY BOTH BONE FORMING AND NON BONE FORMING LESIONS

J. S. Khurana*, S. Ogino, T. McHale, M. Feldman, U. Scherbel, P. Wirganowicz, P. Schultz, B. A. Alman

Dept. of Pathology, U. Pennsylvania, Philadelphia, PA, USA; Dept. Orthopedics, U. Pennsylvania, Philadelphia, PA, USA; Dept. Orthopedics, Hospital for Sick Children, Toronto, Canada

Diseases of Bone

P54 S
HUMORAL HYPERCALCEMIA OF MALIGNANCY: SCID/BEIGE MOUSE MODEL OF ADULT T-CELL LYMPHOMA (ATL) INDEPENDENT OF HTLV-1 TAX EXPRESSION

V. Richard, M. D. Lairmore, P. L. Green, G. Feuer, R. S. Erbe, B. Albrecht, C. D'Souza, E. T. Keller, J. Dai, T. F. Rosol*

Ohio State University, Columbus, OH, USA; SUNY Upstate Med. Univ., Syracuse, NY, USA; University of Michigan, Ann Arbor, MI, USA

 
P57 S
FEMORAL AND LUMBAR SPINE BMD CHANGES IN PATIENTS WITH PRIMARY HYPERPARATHYROIDISM: DIFFERENT IMPROVEMENTS FOLLOWING SUCCESSFUL PARATHYROIDECTOMY IN MALE AND FEMALE PATIENTS

F. Lumachi*, G. Luisetto, A. Nardi, V. Camozzi, V. Masiero, G. Favia

Endocrine Surgery Unit, Dept Surg & Gastroent Sciences, University of Padua, School of Medicine, 35128 Padova, Italy; Division of Endocrinology, Dept Med & Surg Sciences, University of Padua, School of Medicine, 35128 Padova, Italy; Bone Metabolism Unit, City Hospital, Rovigo, Italy

 
P60 S
USEFULNESS OF 99MTC-SESTAMIBI SUBTRACTION SCINTIGRAPHY AND SPIRAL-CT IN PARATHYROID ADENOMAS LOCALIZATION. ANALYSIS OF RESULTS IN PATIENTS WHO UNDERWENT SUCCESSFUL PARATHYROIDECTOMY

F. Lumachi*, P. Zucchetta, G. Luisetto, F. Angelini, R. Behboo, M. C. Marzola, G. Favia

Endocrine Surgery Unit, Dept Surg & Gastroent Sciences, University of Padua, School of Medicine, Padova, Italy; Nuclear Medicine Service; Division of Endocrinology, University of Padua, School of Medicine, 35128 Padova, Italy; Radiology Service, City Hospital, 35128 Padova, Italy

 
P63 S
THE EFFECT OF ALENDRONATE ON LONG BONE GROWTH AND GROWTH PLATE IN THE OIM MOUSE MODEL FOR OSTEOGENESIS IMPERFECTA

K. D. Evans*, R. B. Martin, S. T. Lau, A. M. Oberbauer

Department of Animal Science, University of California Davis, Davis, CA, USA; Orthopaedic Research Laboratories, UC Davis Medical Center, Sacramento, CA, USA

 
P66 S
THE BRITTLE MOUSE MODEL FOR NON-LETHAL OSTEOGENESIS IMPERFECTA HAS DECREASED BONE DENSITY, BONE FORMATION RATE AND FEMUR STRENGTH

J. C. Marini*, C. Bergwitz, A. Forlino, E. P. Frankenburg, K. M. Kozloff, S. A. Goldstein, M. Nahounou, G. Gronowicz

Heritable Disorders Branch, NICHD, NIH, USA; Orthopedic Research Labs, U Michigan School of Medicine, USA; Dept of Orthopedics, U Conn Health Center, USA

 
P69 S
LONG-TERM FOLLOW UP OF BONE MASS IN TREATED ADDISON’S DISEASE

E. Jodar*, G. Martínez, S. Azriel, A. Serraclara, E. De Juan, M. Ruiz Valdepeñas, F. Hawkins

Servicio Endocrinología, Hospital Universitario 12 de Octubre, Madrid

 
P72 S
PRELIMINARY REPORT: STUDY OF BONE MASS AND MINERAL METABOLISM IN CHRONIC HEPATITIS C MALE PATIENTS TREATED WITH ALPHA-INTERFERON AND RIBAVIRIN

G. Martínez*, E. Jodar, A. Soto, F. Hawkins, J. A. Solis-Herruzo

Service of Endocrinology, Hospital 12 de Octubre, Madrid; Service of Gastroenterology, Hospital 12 de Octubre, Madrid

 
P75 S
THE PATHOGENESIS OF POST-TRANSPLANT (TX) OSTEODYSTROPHY AS DETECTED BY EARLY ALTERATIONS IN BONE REMODELING

E. Rojas*, R. Carlini, P. Clesca, A. Arminio, J. R. Weisinger, K. A. Hruska, E. Bellorin-Font

Division of Nephrology, Hospital Universitario de Caracas, Venezuela; Renal Division, Washington University Medical School, St. Louis, MO, USA

 
P78 S
DETERMINATION OF BIOCHEMICAL MARKERS OF BONE METABOLISM IN TYPE 2 DIABETES MELLITUS PATIENTS

G. Y. Zhang*, H. Song, Y. Xue

Department of Endocrinology, Beijing Ji Shui Tan Hospital

 
P81 S
BONE HISTOMORPHOMETRY IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE

G. Lehmann*, T. Eidner, G. Stein, G. Hein

Dept. of Internal Medicine IV, Rheumatology & Osteology, University of Jena, Germany

 
P84 S
WADDLING GAIT AND INVALIDATING RICKETS AS PRESENTING SIGNS OF HEREDITARY TYROSINEMIA TYPE 1

D. Rigante, E. Holme, G. Segni, A. Stabile, P. Caradonna*

Dept. of Pediatrics, UCSC, Rome, Italy; Dept. of Int. Medicine and Geriatrics, UCSC, Rome, Italy; Dept. of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden

 
P87 S
IL-6 IS INVOLVED IN BONE REMODELING AFTER KIDNEY TRANSPLANTATION

V. Kusec*, R. Smalcelj, D. Rogic, Z. Puretic

Central Laboratory, Dialysis Unit, University Hospital Zagreb, Zagreb, Croatia

 
P90 S
ACQUIRED HYPOPHOSPHATEMIC ONCOGENIC OSTEOMALACIA: PROBLEMS OF DIAGNOSIS, TREATMENT AND LONG-TERM MANAGEMENT

G. P. R. Clunie*, P. E. Fox, T. C. B. Stamp

Division of Bone and Mineral Metabolism, Royal National Orthopaedic Hospital, Stanmore Middlesex HA7 4LP, UK

 
P93 S
HYPOVITAMINOSIS D MYOPATHY CHARACTERISED BY 31P MR SPECTROSCOPY

H. Glerup*, H. Stødkilde-Jørgensen, E. F. Eriksen

Dept of Endocrinol and Metab C, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark; MR-Center, Skejby Sygehus, Aarhus University Hospital, Aarhus, Denmark

 
P96 S
SEVERE OSTEOMALACIA WITH NORMAL BONE BIOCHEMISTRY PRESENTING AS OSTEOARTHRITIS

G. A. Campbell

Addenbrookes Hospital, Cambridge, UK

 
P99 S
A CASE OF NEURAPRAXIA SECONDARY TO MYOSITIS OSSIFICANS PROGRESSIVA, TREATED WITH RADIOTHERAPY

M. Druce*, V. H. Morris, T. C. B. Stamp

Watford General Hospital, Watford, UK; University College London Hospital, London, UK; Royal National Orthopaedic Hospital, Stanmore, UK

 
P102 S
DIFFERENTIAL DIAGNOSTICS OF INHERITED CONNECTIVE TISSUE DISEASES AND CONTRIBUTION OF CLINICAL, RADIOGRAPH, DENSITOMETRIC AND BIOCHEMICAL EXAMINATIONS TO THE DIAGNOSTIC PROCEDURE

V. Vyskocil*, J. Varvarovska, J. Vyskocilova, K. Koudela, O. Topolcan

Department of Bone Disease; Department of Pediatric; Department of Orthopaedic Surgery; Department of Tuberculosis Respiratory Disease; Deparment of Immunobiochemistry

 
P105 S
A RARE FORM OF MELORHEOSTOSIS TREATED WITH BISPHOSPHONATE

J. Donáth*, B. Fornet, M. Szilágyi, M. Bély, Gy Poór

National Institute of Rheumatology and Physiotherapy, Budapest, Hungary; Haynal Imre University of Health, Budapest, Hungary; National Institute of Rheumatology and Physiotherapy, Budapest, Hungary; Hospitaller Brothers of St John of God in Budapest, Budapest, Hungary; National Institute of Rheumatology and Physiotherapy, Budapest, Hungary

 
P108 S
ANGIOGENESIS AND EXPRESSION OF ALPHA-SM ACTIN IN FIBROUS DYSPLASIA OF BONE

M. Riminucci*, A. Corsi, S. Kuznetsov, S. Licci, P. Gehron Robey, P. Bianco

Università dell'Aquila, Italy; CSDB, NIDR, NIH, Bethesda, USA; Università "La Sapienza", Roma, Italy

 
P111 S
31P-NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY IN HYPOPHOSPHATASIA: DIAGNOSTIC URINE PROFILE INDICATING MULTIPLE NEW SUBSTRATES FOR BONE ALKALINE PHOSPHATASE

M. P. Whyte*, M. N. Podgornik, A. D'Avignon

Center for Metabolic Bone Disease and Molecular Research, Shriners Hospitals for Children, St. Louis, Missouri, USA; Department of Chemistry, Washington University, St. Louis, Missouri, USA

 
P114 S
RECENT CHANGES IN PAGET'S DISEASE OF BONE CLINICAL EXPRESSIVENESS

A. A. Morales-Piga*, F. J. Bachiller-Corral, V. Abraira, J. Beltran, A. Rapado

Rheumatology, Ramón y Cajal Hospital, Madrid, Spain; Investigation Unit, Ramón y Cajal Hospital, Madrid, Spain; Mineral Metabolism Unit, Fundación Jiménez Díaz; Madrid, Spain

 
P117 S
ALTERED TYPE I AND TYPE III COLLAGEN METABOLISM IN THE MINERALISED MATRIX OF BONE AFFECTED BY PAGET'S DISEASE

H. A. Eriksen*, C. A. Sharp, M. W. J. Davie, J. Risteli

Department of Clinical Chemistry, University of Oulu, Oulu, Finland; Charles Salt Centre, Robert Jones & Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, UK

 
P120 S
CANINE PROSTATE INDUCES NEW BONE FORMATION IN MOUSE CALVARIA - A MODEL OF OSTEOINDUCTION BY PROSTATE TISSUE

B. E. LeRoy, R. R. Bahnson, T. J. Rosol*

The Ohio State University, Columbus, OH, USA

 
P123 S
Withdrawn

Genetics

P126 S
BONE MASS DIFFERENCES BETWEEN 9-YEAR OLD BLACK AND WHITE, URBAN SOUTH AFRICAN CHILDREN

S. A. Norris*, J. M. Pettifor, N. Cameron, T. De Wet, L. Vidulich, E. Cumin

University of the Witwatersrand, RSA; University of Loughborough, UK

 
P129 S
THE GENOTYPIC COMPONENT AFFECTS MAINLY CORTICAL BONE OF YOUNG OSEOPOROTIC SUBJECTS

C. Baudoin, M. Cohen-Solal, J. Beaudreuil, M. C. de Vernejoul*

INSERM U 349, Paris, France; Fédération de Rhumatologie, Paris, France

 
P132 S
POLYMORPHISM AT THE SP 1 BINDING SITE IN THE COLLAGEN (COL1A1) GENE AND DOES NOT PREDICT BONE MINERAL DENSITY IN POSTMENOPAUSAL CANARIAN WOMEN

M. Sosa*, A. Torres, E. Salido, D. Hernández, M. Benítez, J. Gómez, Y. Barrios, P. Betancor

University of Las Palmas de Gran Canaria, Hospital University Insular, Service of Internal Medicine; University of La Lagun, Investigation Unit; University of Las Palmas de Gran Canaria, Hospital Dr. Negrín, Service of Internal Medicine

 
P135 S
RELATIONSHIP BETWEEN COLLAGEN I ALPHA 1 SP1 AND VITAMIN D RECEPTOR GENE POLYMORPHISMS AND THE DEVELOPMENT OF BONE FRACTURES AFTER LIVER TRANSPLANTATION

A. Monegal*, L. Alvarez, M. J. Martínez de Osaba, J. Oriola, N. Guañabens, P. Peris, T. Ferró, A. Rimola, L. Grande, J. Muñoz-Gómez

Hospital Clinic, University of Barcelona, IDIBAPS, Spain

 
P138 S
SP1 BINDING SITE POLYMORPHISM DISTRIBUTION OF THE COLLAGEN TYPE I ALPHA 1 GENE AND ITS CORRELATION WITH BONE MINERAL DENSITY IN A YOUNG BRAZILIAN WOMEN POPULATION

E. R. Barros*, O. M. Hauache, A. C. Ramalho, J. G. H. Vieira, M. Lazaretti-Castro

Division of Endocrinology- Universidade Federal de São Paulo, Brazil

 
P141 S
POLYMORPHISMS IN THE ESTROGEN RECEPTOR ALFA ARE ASSOCIATED WITH SERUM LEVELS OF ESTRADIOL AFTER MENOPAUSE AND EARLY POSTMENOPAUSAL BONE LOSS BUT NOT WITH PEAK BONE MASS OR RESPONSE TO HRT

B. L. Langdahl*, P. Vestergaard, B. Abrahamsen, C. Brot, P. Eiken, S. P. Nielsen, O. H. Sørensen, H. Beck-Nielsen, L. Mosekilde, E. F. Eriksen

Dept of Endocrinology and Metabolism, Aarhus University Hospital, Aarhus Amtssygehus, Denmark; Danish Osteoporosis Prevention Study Group

Hormones and Cytokines

P144 S
CALICITONIN-RELATED PEPTIDES ACTIVATE PROTEIN KINASE C IN HUMAN OSTEOBLAST-LIKE CELLS

I. Villa*, C. Dal Fiume, F. Pagani, S. Rubinacci, F. Guidobono

Bone Metabolic Unit Scientific Institute H San Raffaele, Milan, Italy; Dept. of Pharmacology, Chemotherapy and Medical Toxicology, University of Milan, Italy

 
P147 S
A NEW MUTATION IN THE EXTRACELLULAR AMINO-TERMINAL DOMAIN OF THE CALCIUM-SENSING RECEPTOR CAUSING FAMILIAL HYPERCALCIURIC HYPOCALCEMIA

S. Mora*, M. C. Proverbio, L. Bolzoni, G. Colussi, J. Hu, K. Jones, A. M. Spiegel

Laboratory of Pediatric Endocrinology, IRCCS S. Raffaele, University of Milan, Italy; Renal Unit, Niguarda Ca’ Granda Hospital, Milan, Italy; Metabolic Diseases Branch, NIDDK, National Institutes of Health, Bethesda, USA

 
P150 S
THE COMBINATION OF PAMIDRONATE WITH INTERFERON-ALPHA INDUCES BONE FORMATION IN PATIENTS WITH MULTIPLE MYELOMA IN PLATEAU PHASE

E. Terpos*, N. Viniou, G. Vaiopoulos, J. Meletis, X. Yataganas

First Department of Internal Medicine, University of Athens Medical School, Laiko General Hospital, Athens, Greece

 
P153 S
BREAST CANCER CELL OSTEOPONTIN EXPRESSION, CONNEXIN PROFILE AND GAP JUNCTIONAL COMMUNICATION WITH OSTEOBLASTIC CELLS CORRELATES WITH METASTATIC POTENTIAL

H. J. Donahue*, M. M. Saunders, Z. Li, E. Kunze, A. Mastro, D. R. Welch

Musculoskeletal Research Laboratory, Department of Orthopaedics, Pennsylvania State Uiversity, Hershey, PA, USA

 
P156 S
CHARACTERIZATION OF CAPACITATIVE CALCIUM INFLUX IN TUMORAL HUMAN EPITHELIAL BREAST CELLS

G. Picotto, A. Russo de Boland, R. L. Boland*

Dept. Biologia, Bioquimica & Farmacia - Universidad Nacional del Sur, Bahia Blanca, Buenos Aires, Argentina

 
P159 S
ASSESSMENT OF MAST CELLS MAY HELP IN THE DIFFERENTIAL DIAGNOSIS OF REACTIVE LESIONS AND PRIMARY BONE TUMOURS

C. J. Joyner*, T. Yang, A. Reed, N. A. Athanasou

Nuffield Department of Orthopaedic Surgery, University of Oxford, UK

 
P162 S
GENES THAT REGULATE BREAST CANCER METASTASIS TO BONE

M. D. Tavaria*, M. Lelekakis, A. Natoli, E. Sloan, P. Ho, D. Hards, T. J. Martin, J. M. Moseley, R. L. Anderson

Peter Mac Callum Cancer Institute, Melbourne, Australia; St Vincent's Institute of Medical Research, Melbourne, Australia

 
P165 S
EXTRACELLULAR CALCIUM INDUCED ESTROGEN-LIKE ACTIVITY IN MCF-7 BREAST CANCER CELLS

F. Journé*, J. C. Dumon, N. Kheddoumi, I. Laïos, Y. Ma, G. Leclercq, J. J. Body

Laboratory of Endocrinology and Breast Cancer, Brussels, Belgium

 
P168 S
CLINICAL AND BIOCHEMICAL EFFECTS OF A SHORT-TERM IBANDRONATE TREATMENT IN CANCER PATIENTS WITH OPIOID-RESISTANT METASTATIC BONE PAIN

J. C. Dumon*, I. Mancini, J. J. Body

Laboratory of Endocrinology and Breast Cancer, and Clinic of Suppportive Care

 
P171 S
EFFECTS OF POLYETHYLENE AND ALPHA-ALUMINA PARTICLES ON IL-6 EXPRESSION AND SECRETION IN PRIMARY CULTURES OF HUMAN OSTEOBLASTIC CELLS

A. M. Rodrigo*, M. E. Martínez, L. Saldaña, G. Vallés, P. Martínez, J. L. González-Carrasco, J. Cordero, L. Munuera

Investigation Unit. La Paz Hospital.; Biochemical Division. La Paz Hospital.; National Center for Metallurgical Research (CENIM); Orthopaedic Department. La Paz Hospital

 
P174 S
EFFECTS PRODUCED BY 17-BETA ESTRADIOL, RALOXIFENE AND TAMOXIFEN ON IL-6 RELEASE AND GENE EXPRESSION BY HUMAN OSTEOBLASTS IN CULTURE

C. Méndez-Dávila*, C. García-Moreno, M. L. Traba, C. Turbí, C. De la Piedra

Fundación Jiménez Díaz. Biochemistry Laboratory. Madrid, Spain; Lilly Laboratories, 28108. Alcobendas, Spain

 
P177 S
FRACTURE HEALING SLOWS WITH AGE WITH PROLONGED EXPRESSION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN THE RAT

R. A. Meyer*, B. J. Desai, M. H. Meyer, S. Porter, J. F. Kellam

Dept. Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC, USA

 
P180 S
THE EFFECT OF INSULIN-LIKE-GROWTH FACTOR-I ON THE PROLIFERATION AND DIFFERENTIATION OF TRABECULAR BONE DERIVED CELLS IN VITRO

J. F. Evans, D. Sima, C. Tapiador, J. K. Yeh*

Winthrop- University Hospital, Mineola, NY, USA

 
P183 S
PLASMA CATECHOLAMINES AND PARATHYROID HORMONE DURING ENDURANCE EXERCISE

J. Guillemant*, C. Accarie, G. Pérès, S. Guillemant

Faculté de Médecine Pitié-Salpêtrière, Paris, France; EPHE, Nutrition Hydrominérale, France; Médecine du Sport, Hôpital de La Pitié, Paris, France

 
P186 S
INTRACELLULAR LOCALIZATIN OF GREEN FLUORESCENT PROTEIN-PTH RECEPTOR CONSTRUCTS IN CULTURED LLC-PK1 CELLS: TARGETED MUTAGENESIS OF THE PUTATIVE NUCLEAR LOCALIZATION SEQUENCE

E. Patterson*, L. Canaff, G. N. Hendy, A. B. Hodsman, L. J. Fraher, P. H. Watson

Department of Biochemistry, University of Western Ontario, London, Canada; Calcium Research Laboratory, McGill University, Montreal Canada; Department of Medicine, University of Western Ontario, London, Canada

 
P189 S
MECHANISM OF THE EFFECT OF RETINOIC ACID ON PARATHYROID HORMONE STIMULATED ADENYLATE CYCLASE ACTIVITY

E. A. Gonzalez*, C. L. McConkey, K. J. Martin

Saint Louis University

 
P192 S
ALUMINIUM INHIBITS NOT ONLY PTH RELEASE BUT ALSO PTH SYNTHESIS (MRNA OF PRE-PTH). IN VIVO AND IN VITRO RESULTS

J. L. Fernandez-Martin*, M. Naves, C. Diaz-Corte, M. T. Fernandez-Coto, J. B. Cannata

Bone and Mineral Research Unit, Instituto Reina Sofía de Investigación, Hospital Central de Asturias, Oviedo, Asturias, Spain

 
P195 S
BONE TISSUE IS A TARGET FOR LUTEINISING HORMONE (LH)

S. J. Yarram*, K. Westby, P. Roche, M. Perry, J. R. Sandy, J. P. Mansell

The University of Bristol, UK; The MAYO Clinic, Rochester, USA

Osteoblasts

P198 S
THE EFFECTS OF THE FRACTURE-HEALING STIMULIN (JIN PU YE) ON OSTEOBLASTS IN VITRO

J. M. Zhu*, H. Fang, X. G. Chen

Department of Orthopedics, Shanghai 8th Hospital, Shanghai-200233, PR China

 
P201 S
ACTIONS AND INTERACTIONS OF ER-ALPHA AND ER-BETA IN THE ESTROGEN REGULATION OF HUMAN OSTEOBLAST FUNCTIONS

T. C. Spelsberg*, D. J. Rickard, D. G. Monroe, K. M. Waters, B. L. Riggs, S. Khosla, M. Subramaniam

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA; Department of Internal Medicine, Division of Endocrinology, Mayo Clinic, Rochester, MN, USA

 
P204 S
THE STIMULATING EFFECT OF IMMUNOSUPPRESSANT FK506 ON OSTEOBLAST DIFFERENTIATION AND ITS APPLICATION TO TISSUE ENGINEERING IN BONE

T. Uemura*, M. H. Lee, J. Dong, H. Kojima, D. Iejima, P. C. Wang, T. Yoshikawa, K. Ichijima, T. Tateishi

NAIR; CREST, JST; Kyungpook Natl. Univ.; Tsukuba Univ.; Nara Med. Univ.

 
P207 S
THE HEPARIN-BINDING GROWTH FACTORS PLEIOTROPHIN, MIDKINE AND CYR61 ARE DIFFERENTIALLY REGULATED DURING OSTEOGENIC DIFFERENTIATION OF SAOS-2 CELLS

H. Hausser*, R. Brenner

Division for Biochemistry of Joint and Connective Tissue Diseases, University of Ulm, Ulm, Germany

 
P210 S
REGULATION OF GROUP-C SOX MRNAS IN OSTEOBLASTS

S. Reppe*, O. K. Olstad, E. Rian, V. T. Gautvik, K. M. Gautvik, R. Jemtland

University of Oslo, Oslo, Norway; The Norvegian Radium Hospital, Oslo, Norway

 
P213 S
OSTEOBLAST PHOSPHATE (PI) TRANSPORT AND PI TRANSPORTER MRNA REGULATION BY EXTRACELLULAR PI IN VITRO

E. Zoidis*, C. Ghirlanda, M. Gosteli-Peter, J. Zapf, C. Schmid

Division of Endocrinology and Diabetes, Department of Internal Medicine, University Hospital of Zurich, CH-8091 Zurich, Switzerland

 
P216 S
ASSESSMENT OF THE UTILITY OF STRO-1, HOP-26, CD166 AND CD49A AS DEVELOPMENTAL MARKERS FOR HUMAN CELLS OF THE OSTEOGENIC LINEAGE

K. Stewart*, J. N. Beresford

University of Bath, Bath, UK

 
P219 S
CAVEOLIN-1 EXPRESSION IN HUMAN OSTEOBLASTS, BONE MARROW AND PERIPHERAL BLOOD MONONUCLEAR CELLS: IMPLICATIONS FOR THE ROLE OF CAVEOLAE IN BONE GROWTH AND DISEASE

G. A. Burke*, S. McHenry, D. Marsh, G. Li

Department of Trauma and Orthopaedics, Queen’s University Belfast, Northern Ireland

 
P222 S
MICROSTRUCTURAL INVESTIGATIONS ON STRAIN-RELATED COLLAGEN MINERALIZATION

U. Meyer*, U. Joos, J. Handschel, J. Jäsche, U. Stratmann, H. P. Wiesmann

Biomineralisation Research Group, Clinic of Maxillofacial Surgery, University of Münster, Germany; Institute of Anatomy, University of Münster, Germany

 
P225 S
Withdrawn

 
P228 S
MECHANICAL STIMULATION CHANGES THE EXPRESSIONS OF TGF-BETA1 AND OPN MRNAS IN UMR-106 CELLS BY IN SITU HYBRIDIZATION

D. W. Liu*, M. K. Fu, S. L. Li

Department of Orthodontics, School of Stomatology, Beijing Medical University, Beijing, P.R. China; Department of Oral Surgery, School of Stomatology, Beijing Medical University, Beijing, P.R. China

 
P231 S
ACTIVATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN OSTEOBLASTS BY PRO-INFLAMMATORY CYTOKINES INVOLVES ACTIVATION OF AKT

R. J. van 't Hof*, M. E. Gallagher, S. H. Ralston, M. H. Helfrich

University of Aberdeen, Aberdeen, UK

 
P234 S
MORPHOLOGICAL BEHAVIOR OF OSTEOBLAST-LIKE CELLS ON SURFACE MODIFIED TITANIUM IN VITRO

Y. Yang*, J.Tian

Beijing Fine Ceramics Lab., Tsinghua University, P. R. China

 
P237 S
CYTOTOXICITY TESTING OF NITI IN ROS-17 CULTURES

A. Kapanen*, J. Ryhanen, J. Ilvesaro, A. Danilov, J. Tuukkanen

Dept. of Anatomy and Cell Biology, Univ. of Oulu, Finland; Dept. of Surgery, Univ. of Oulu, Finland

 
P240 S
PTHrP STIMULATES OSTEOGENIC CELL PROLIFERATION THROUGH A PKC-DEPENDENT ACTIVATION OF THE RAS/MAP KINASE SIGNALING PATHWAY

D. Miao*, X-K. Tong, G. Chan, D. Panda, P. S. McPherson, D. Goltzman

Dept. of Medicine, McGill University, Montreal, QC, Canada; Dept. of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada

 
P243 S
THE EFFECT OF THERAPEUTIC ULTRASOUND ON BONE REMODELLING: ROLE IN OSTEORADIONECROSIS

S. Meghji*, P. Reher, N. Doan, N. Ghazali, R. Ramli, M. Harris

Department of Oral and Maxillofacial Surgery, Eastman Dental Institute, UCL, 256 Gray's Inn Road, London WC1X 8LD, UK

 
P246 S
CHARACTERIZATION OF A HUMAN PERIOSTEAL CELL LINE (HPOB-TERT) AS A PROMISING MODEL FOR BONE FORMATION

E. Federici*, C. Darimont, O. Avanti, Y. Tromvoukis, A. Pfeifer, E. Offord

Nestlé Research Center, Lausanne, Switzerland

 
P249 S
INTERLEUKIN-11 PROMOTES OSTEOBLAST DIFFERENTIATION VIA JAK/STAT SIGNAL TRANSDUCTION PATHWAY

C. Shih*, J. H. Lai

Department of Biology and Anatomy, National Defense Medical Center, Taipei, ROC

 
P252 S
MODULATION OF THE PURINERGIC CA² SIGNALING PATHWAY IN OSTEOBLASTS BY OLPADRONATE AND ITS NON-ANTIRESORPTIVE DERIVATIVE IG-9402: EVIDENCE ON THE EXISTENCE OF A SPECIFIC BISPHOSPHONATE RECEPTOR

G. Vazquez, G. Santillán, R. L. Boland*, E. Roldán, A. Pérez-Lloret

Dept. Biologia, Bioquimica & Farmacia - Universidad Nacional del Sur, Bahia Blanca, Buenos Aires, Argentina; Gador S.A., Buenos Aires, Argentina

 
P255 S
Withdrawn

 
P258 S
EFFECT OF OVARIECTOMY ON DEXAMETHASONE- AND PROGESTERONE-DEPENDENT OSTEOPROGENITORS IN CELL POPULATIONS DERIVED FROM VERTEBRAE AND PROXIMAL FEMURS OF FEMALE RATS

W. Pei*, C. G. Bellows, E. S. Elsubeihi, J. N. M. Heersche

Faculty of Dentistry, University of Toronto, Canada

Osteoclasts

P261 S
BONE RESORPTION RELEASES IMMUNOREACTIVE OSTEOCALCIN FROM BONE MATRIX IN VITRO

K. Ivaska*, T. Heino, T. Hentunen, H. K. Väänänen

Institute of Biomedicine, Department of Anatomy, University of Turku, Turku, Finland

 
P264 S
MACROPHAGE-DEACTIVATING MOLECULES, TRANSFORMING GROWTH FACTOR BETA₁ (TGF-BETA), INTERLEUKIN (IL) -4 AND IL-13 STIMULATE THE OSTEOCLAST-FORMING POTENTIAL OF PERIPHERAL BLOOD HAEMOPOIETIC PRECURSORS IN A LYMPHOCYTE-RICH MICROENVIRONMENT

H. M. Massey*, M. A. Horton, A. M. Flanagan

Bone and Mineral Unit, University College, London, UK; Royal Free and University College Medical School, London, UK

 
P267 S
HIGH CONCENTRATIONS OF MACROPHAGE COLONY STIMULATING FACTOR AND HIGH MONOCYTE DENSITIES INHIBIT THE FORMATION OF TARTRATE-RESISTANT ACID PHOSPHATASE-POSITIVE OSTEOCLAST-LIKE CELLS

M. N. Rowlands*, C. A. Sharp, M. J. Marshall

Charles Salt Centre, Oswestry, UK

 
P270 S
FLT3 LIGAND CAN SUBSTITUTE FOR M-CSF IN SUPPORT OF OSTEOCLAST DIFFERENTIATION AND FUNCTION

J. M. Lean*, K. Fuller, S. W. Fox, T. J. Chambers

St George's Hospital Medical School, London, UK

 
P273 S
INTERLEUKIN-6, LEUKEMIA INHIBITORY FACTOR AND ONCOSTATIN M STIMULATE BONE RESORPTION AND REGULATE THE EXPRESSION OF RANKL, OPG AND RANK IN MOUSE CALVARIAE

E. Persson*, P. Palmquist, H. H. Conaway, P. Lundberg, U. H. Lerner

Dept. Oral Cell Biology, Umeå University, Umeå, Sweden; Centre for Musculoskeletal Research, National Institute for Working Life, Umeå, Sweden; Dept. Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

 
P276 S
IMMUNOLOCALIZATION OF OSTEOCLAST DIFFERENTIATION FACTOR IS ASSOCIATED WITH THE OSTEOCLAST DEVELOPMENT IN RAT PERIODONTIUM

S. Kawamoto*, S. Ejiri, K. Hoshi, E. Nagaoka, H. Ozawa

Kagoshima University, Kagoshima, Japan; Niigata University, Niigata, Japan

 
P279 S
EXPRESSION OF MSP RECEPTOR RON IN OSTEOCLAST-LIKE GCT CELL LINES

C. Camerino*, M. Santoro, G. Mori, M. Grano, P. C. Marchisio, G. Gaudino, A. Zambonin Zallone

Dept. of Human Anatomy, Univ. of Bari, Italy; University A. Avogadro, Novara, Italy; DIBIT, San Raffaele Milano, Italy

 
P282 S
APICAL EXOCYTOSIS OF LYSOSOMAL PROTEINS INVOLVES MATRIX TRANSCYTOSIS IN BONE-RESORBING OSTEOCLASTS

S. A. Nesbitt*, P. P. Lehenkari, S. E. Gschmeisser, M. A. Horton

University College London, London, UK; Oulu University, Oulu, Finland; ICRF, London, UK

 
P285 S
INDUCTION OF HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS TO DIFFERENTIATE INTO RESORBING OSTEOCLASTS

T. A. Hentunen*, H. K. Vaananen

University of Turku, Turku, Finland

 
P288 S
RECOMBINANT G-PROTEIN OF VS-VIRUS IS TARGETED TO THE RUFFLED BORDER IN OSTEOCLASTS

M. T. K. Mulari*, L. Patrikainen, K. Metsikkö, H. K. Väänänen

Inst. of Biomedicine, Dept. of Anatomy, Univ. of Turku, Finland; Dept. of Anatomy, Univ. of Oulu, Finalnd

 
P291 S
A METABOLITE OF CLODRONATE, APPCCL₂P, CAUSES OSTEOCLAST APOPTOSIS AND INHIBITS BONE RESORPTION IN VITRO

J. C. Frith*, J. Monkkonen, M. J. Rogers

Dept of Medicine and Therapeutics, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, UK.; Dept of Pharmaceutics, University of Kuopio, Kuopio, Finland

 
P294 S
BLOCKADE OF P2X₇ RECEPTORS INHIBITS OSTEOCLAST FUSION IN VITRO

A. Gartland*, J. A. Gallagher, W. B. Bowler

Human Bone Cell Research Group, Dept of Human Anatomy & Cell Biology, The University of Liverpool, Liverpool, UK

 
P297 S
DIETARY LYCOPENE IS INHIBITORY TO REACTIVE OXYGEN SPECIES-MEDIATED RESORPTION BY OSTEOCLASTS

L. G. Rao*, N. Krishnadev, A. Cheng, L. J-F. Liu, T. M. Murray, A. V. Rao

Calcium Research and Bone Biology Laboratory, Division of Endocrinology, St Michael's Hospital & Dept of Medicine, University of Toronto, Canada; Dept of Nutritional Sciences2, Faculty of Medicine, University of Toronto, Canada

 
P300 S
OSTEOCLAST SPREADING IS CORRELATED WITH SPONTANEOUS AND OSCILLATORY ACTIVATION OF A CALCIUM- DEPENDENT POTASSIUM CURRENT (IKCA)

L. Espinosa*, L. Paret, C. Ojeda, C. Itzstein, P. D. Delmas, C. Chenu

Unité INSERM 403, Lyon, France; Unité INSERM 121, Lyon, France

Osteoporosis: Diagnosis

P303 S
DOES SOCIOECONOMIC DEPRIVATION INFLUENCE A PATIENT'S LIKELIHOOD OF BEING REFERRED FOR BONE DENSITOMETRY?

J. Saunders, A. Johansen*, M. Stone, W. Evans, S. Jones, R. Lyons

Collaboration for Accident Prevention and Injury Control, Welsh Combined Centres for Public Health, University Of Wales College of Medicine, Cardiff, UK; Bone Research Unit, Academic Department of Geriatric Medicine, University of Wales College of Medicine, Cardiff, UK; Department of Medical Physics, University Hospital of Wales, Cardiff, UK

 
P306 S
CORRELATION BETWEEN CENTRAL AND PERIPHERAL SKELETON BONE MINERAL DENSITY (BMD) DURING PEAK BONE MASS FORMATION

R. Carvajal, G. Riera-Espinoza*, M. Naressi, G. Velásquez, J. Rámos

UNILIME, Universidad de Carabobo, Hospital Universitario Dr. Angel Larralde, Valencia, Venezuela

 
P309 S
PEAK BONE MASS IN A VENEZUELAN POPULATION. PRELIMINARY REPORT

G. Riera-Espinoza*, R. Carvajal, M. Naressi, G. Velásquez, J. Ramos

UNILIME, Universidad de Carabobo, Hospital Universitario Dr. Angel Larralde, I.V.S.S, Valencia, Venezuela

 
P312 S
RATING OF THE MICRO-CT MEASUREMENT OF HARD TEETH SUBSTANCES FOR THE OSTEOPOROSIS-DIAGNOSIS

L. Kettler*, E. Dr. Paulisch, K. P. Prof. Dr. Lange, M. Dr. Giehl, W. Dr. Gowin, D. Prof. Dr.Felsenberg

Humboldt Universität zu Berlin, GER; Freie Universität Berlin, GER

 
P315 S
REDUCED LUNG FUNCTION IN WOMEN WITH VERTEBRAL FRACTURES

J. A. Falch*, C. Bugge

Osteoporosis Clinic, Aker Hospital, Oslo, Norway

 
P318 S
COMPARISON OF ATTITUDES TO OSTEOPOROSIS IN TWO REGIONS OF THE EUROPEAN COMMUNITY

J. C. Taylor*, G. P. R. Clunie, A. M. Scarponi, D. O'Reilly, F. Vecchini, E. Mannarino, J. C. Chamberlain, H. Fitz-Clarence

Osteoporosis Unit, Centre for Rheumatology, UCLH, London, UK; Rheumatology Dept., Ipswich Hospital NHS Trust, Ipswich, Suffolk, UK; Osteoporosis Centre, University of Perugia, Umbria, Italy; Rheumatology Dept., West Suffolk NHS Trust, Bury St. Edmunds, Suffolk, UK

 
P321 S
ACCURACY IN WEIGHT MEASUREMENT WITH HOLOGIC QDR 4500 ACCLAIM

B. Sutter*, O. Legrand, E. Meys, F. Bougon, P. Hardouin

Institut Calot, Berck/Mer, France

 
P324 S
INTRAINDIVIDUAL COEFFICIENT OF VARIATION OF LUMBAR SPINE DENSITY AS AN INDEX OF SPONDYLOTIC DEFORMITY

T. Fujita*, Y. Fujii, A. Miyauchi, Y. Takagi

Calcium Research Institute; Katsuragi Hospital; National Sanatorium Hyogo Chuo Hospital

 
P327 S
TOTAL HIP OR FEMORAL NECK? DIFFERENCES IN WHO CLASSIFICATION IN POSTMENOPAUSAL WOMEN

J. L. Mansur

Centro de Endocrinologia y Osteoporosis La Plata, Argentina

 
P330 S
NURSE-LED PRIMARY CARE BASED OSTEOPOROSIS SCREENING OF POST-MENOPAUSAL WOMEN USING PERIPHERAL BONE DENSITOMETRY AND RISK ASSESSMENT QUESTIONNAIRE

A. H. Franklin-Stevens*, L. Cheng, M. Froome, J. Taylor, M. E. Shipley, J. C. Chamberlain, H. Fitz-Clarence

Osteoporosis Unit, Centre for Rheumatology, UCLH, London, UK.; Riomed Ltd., Southampton, UK

 
P333 S
Withdrawn

 
P336 S
DIGITAL X-RAY RADIOGRAMMETRY ON HAND X-RAYS OBTAINED ON MAMMOGRAPHIC X-RAY EQUIPMENT

M. Friis*, N. Skovgaard, K. Juul, D. S. Nissen

Department for Diagnostic Radiology and Ultrasound, Glostrup Hospital, Denmark; Clinical Research and Development, Pronosco, Denmark

 
P339 S
ROLE OF QUANTITATIVE EXAMINATION OF BONES (SUNLIGHT OMNISENSE) IN DISCRIMINATION OF WOMEN WITH LOW FRACTURE-RISK DESPITE LOW BMD (DEXA)

L. Papierska*, W. Misiorowski, S. Zgliczyñski

Medical Center for Postgraduate Medicine, Department of Endocrinology, Warsaw, Poland

 
P342 S
THE NATURE OF CHANGES IN VERTEBRAL BODY TRABECULAR BONE IN OSTEOPOROSIS

A. Boyde

University College, London, UK

 
P345 S
SHOULD BE FEASIBLE TO EXCHANGE 2-H FASTING URINE AND 24-H URINE SAMPLES FOR DETERMINATION OF CLASSICAL RESORPTION BIOCHEMICAL MARKERS?

J. Ferrer-Cañabate*, I. Tovar, P. Martinez

Servicio AA.CC. H.U. Virgen Arrixaca, Murcia, Spain

 
P348 S
THE LEVELS OF VITAMIN K ANALOGUES IN OSTEOPOROTIC AND OSTEOARTHRITIS PATIENTS SAMPLES DETERMINED BY THE SENSITIVE AND SIMPLE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH ECD METHOD

H. Wakabayashi*, H. Hirata, K. Onodera, T. Yamamoto, T. Tanizawa, S. Sato, T. Kusano

Niigata College of Pharmacy, Niigata, Japan; Okayama University, Okayama, Japan; Shinrakuen Hospital, Niigata, Japan; Tominaga-Kusano Hospital, Sanjo, Japan

 
P351 S
SERUM TARTRATE-RESISTANT ACID PHOSPHATASE 5B IS A SPECIFIC AND SENSITIVE MARKER OF BONE RESORPTION

J. M. Halleen*, S. L. Alatalo, A. J. Janckila, S. Cheng, H. Suominen, H. Woitge, M. J. Seibel, H. K. Väänänen

University of Turku, Turku, Finland; Veterans Affairs Medical Center, Louisville, KY, USA; University of Jyväskylä, Jyväskylä, Finland; University of Heidelberg, Heidelberg, Germany

 
P354 S
CHANGES IN BONE MASS AND BONE TURNOVER MARKERS FOLLOWING PREGNANCY AND LACTATION IN MOTHERS OF TERM AND PRETERM INFANTS

C. M. Smith*, R. C. Coombs, R. Eastell

Bone Metabolism Group, University of Sheffield, UK; Neonatal Unit, Northern General Hospital, Sheffield, UK

 
P357 S
A COMPARISON OF THE IMPACT OF FEEDING ON THE BIOLOGICAL VARIABILITY OF BONE TURNOVER MARKERS

J. A. Clowes*, R. A. Hannon, T. S. Yap, N. Hoyle, A. Blumsohn, R. Eastell

Division of Clinical Sciences (NGHT), University of Sheffield, UK; Hoffman La Roche, Penzberg, Germany

 
P360 S
QUANTITATIVE ULTRASONOMETRY (QUS) OF THE OS CALCIS IN POSTMENOPAUSAL WOMEN WITH SPINE AND HIP FRACTURE

P. Hadji*, M. Kalder, K. Bock, U. S. Albert, G. Emons, K. D. Schulz

Philipps-University of Marburg, Marburg, Germany

 
P363 S
EVALUATION OF CALANEAL BONE DENSITY WITH HANDY QUANTITATIVE ULTRASOUND DEVICE IN A JAPANESE POPULATION

K. Yoh*, H. Kisimoto, H. Oota, I. Gorai, J. Hasimoto, S. Yosimoto, Y. Nakatsuka

Orthop Dept., Hyogo College of Medicine; CM100 Multicenter Study Group

 
P366 S
PATIENTS WITH ELECTIVE ARTHROPLASTIES: A HIGH-RISK POPULATION FOR OSTEOPOROSIS

B. J. Edwards*, D. Stulberg, L. Madison, C. Wilson

Northwestern University, Chicago, Illinois, USA; Northwestern Memorial Hospital, Chicago, Illinois, USA

 
P369 S
USEFULNESS OF QUANTATIVE ULTRASOUND FOR EARLY DETECTION OF BONE MASS CHANGE

H. B. Park*, D. M. Kim, C. W. Ahn, S. S. Jeong, J. H. Nam, B. S. Cha, H. C. Lee, K. B. Heo, S. K. Lim

A University, Yonsei, Korea

 
P372 S
PREVALENT APPENDICULAR FRACTURES IN ELDERLY WOMEN WITH NORMAL DEXA BONE MASS ARE ASSOCIATED WITH LOW ULTRASOUND MEASUREMENTS

A. Marangou*, A. Devine, S. S. Dhaliwal, R. L. Prince

Department of Medicine, University of Western Australia; Dept Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Perth, Western Australia

Osteoporosis: Epidemiology

P375 S
PROTEIN NUTRITION AND FEMUR BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN

M. Di Monaco*, R. Di Monaco, M. Manca, A. Cavanna

Presidio Sanitario San Camillo, Torino, Italy; IRES Lucia Morosini, Torino, Italy

 
P378 S
MEAT INTAKE AND OTHER DIETARY DETERMINANTS OF RAPID POST-MENOPAUSAL BONE LOSS FROM THE SPINE

R. Abraham*, J. Walton, A. Nicholls, J. Justice, B. Wardley-Smith, J. Reeve

Clinical Research Centre, Northwick Park Hospital, London HA1 3UJ, UK; Department of Medicine, University of Cambridge, Cambridge CB2 2QQ, UK

 
P381 S
POST-MENOPAUSAL OSTEOPOROTIC FRACTURE AT DISTAL AND PROXIMAL RADIUS WITH LIFESTYLE (ESPECIALLY FOOD RESOURCES AND FOOD INTAKE), ANTHROPOMETRIC, AND MENSTRUAL CHARACTERISTICS

Y. W. Wang*, J. S. Guo, W. C. Wang

Institute of Nutrition and Food Hygiene, CAPM, Beijing, China; Beijing ShunYi Anti-epidemic Station, Beijing, China

 
P384 S
CALCIUM INTAKE FROM MILK AND DIARY PRODUCTS IN WARSAW REGION POPULATION

A. Z. Sawicki*, A. Debinski, J. Charzewska, M. Rogalska-Niedzwiedz, B. Wajszczyk

Mineral Metabolism and Bone Disease Dept., National Food and Nutrition Institute; Dept. of Epidemiology, National Food and Nutrition Institute; Warsaw Osteoporosis and Calcium Metabolism Centre "Osteomed", Warsaw, Poland

 
P387 S
EFFECT OF MATERNAL NUTRITION ON LONG BONE MINERALIZATION IN THE FETAL SHEEP

A. Bailón-Plaza*, K. A. Berghorn, P. W. Nathanielsz, M. C. H. van der Meulen

Department of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA; Laboratory for Pregnancy and Newborn Research, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA

 
P390 S
THE HEALTH OF THE BONES OF SPANISH WOMEN

S. Palacios*, I. Cifuentes, S. von Helde, C. Menéndez, C. Tapia-Ruano, I. Szczedrin

Institute Palacios of Women´s Health, Madrid, Spain

 
P393 S
SURVEY AND ANALYSIS OF FRACTURE PATIENTS IN HARBIN ORTHOPEDICS SURGERY HOSPITAL DURING 1999.10-2000.10

H. H. Zhang*, B. F. Wang, Dan Tian

Unit of Bone Mineral Density, Harbin Orthopedic Surgery Hospital

 
P396 S
EVALUATION OF A CLINICAL SCREENING STRATEGY TO IDENTIFY ELDERLY WOMEN AT VERY HIGH RISK OF HIP FRACTURE: RESULTS FROM THE EPIDOS STUDY

P. Dargent-Molina*, M. N. Douchin, C. Cormier, G. Bréart

INSERM, Villejuif, France; Hopital Cochin, Paris, France

 
P399 S
FRACTURE RISK IN PATIENTS WITH PITUITARY DISEASES

P. Vestergaard*, J. O. L. Jørgensen, C. Hagen, H. C. Hoeck, P. Laurberg, L. Rejnmark, K. Brixen, J. Weeke, L. Mosekilde

Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, Denmark; Department of Endocrinology M, Aarhus University Hospital, Aarhus, Denmark; Department of Endocrinology M, Odense University Hospital, Odense, Denmark; Department of Endocrinology and Internal Medicine, Aalborg Hospital, Aalborg, Denmark

 
P402 S
DIABETIC OSTEOPENIA DIAGNOSTIC IN DIABETIC FOOT DEVELOPMENT RISK PATIENTS

A. P. Katushkina

Minsk Medical Institute, Belarus

 
P405 S
RISK FACTORS FOR CLINICAL FRACTURE IN POSTMENOPAUSAL WOMEN: DATA FROM THE FRACTURE INTERVENTION TRIAL (FIT)

M. C. Hochberg*, P. D. Ross, D. Thompson

University of Maryland, Baltimore, MD, USA; Merck Research Laboratory, Rahway, NJ, USA

 
P408 S
OSTEPOROSIS ON HYPERTENSIVE WOMEN

J. L. Perez-Castrillon*, P. Escudero, I. Justo, J. Silva, R. Igea, M. Martin-Luquero, C. Pueyo, C. Diaz, G. Hernandez, A. Dueñas

Hospital Rio Hortega, Valladolid, Spain; Pfizer, Spain

 
P411 S
BONE MASS IN MALE PATIENTS WITH CORONARY ATHEROSCLEROSIS

C. Valero*, L. Perera, J. A. Riancho, J. A. Amado, J. M. Olmos, J. González-Macías

Dept. Internal Medicine, Hospital M. Valdecilla, Santander, Spain

 
P414 S
PARKINSON DISEASE AND BONE MINERAL DENSITY: A PRELIMINARY STUDY

G. Sahin*, A. Ozge, S. Bagis, A. Bicer, O. Bolgen Cimen, C. Erdogan

Mersin University, School of Medicine, Department of Physical Medicine and Rehabilitation, Mersin, Turkey; Mersin University, School of Medicine, Department of Neurology, Mersin, Turkey

 
P417 S
HIP FRACTURE RISK ASSESSMENT: AN EVIDENCE-BASED APPROACH COMBINING INDIVIDUAL, EPIDEMIOLOGIC AND DEMOGRAPHIC DATA IN PATIENTS AT RISK FOR OSTEOPOROSIS

J. Hohnloser*, U. Siebert, M. Wildner, T. Kurth, L. Wieczorek

Institute for Medical Informatics, Biometry and Epidemiology, University of Munich Germany; Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, MA, USA; Bavarian Public Health Research Center, Munich, Germany; Brigham and Women's Hospital, Division of Preventive Medicine, Harvard Medical School, Boston, MA, USA; Hoffman-La Roche Pharmaceuticals Integrated Health Care Solutions, Basel, Switzerland

 
P420 S
DECREASED PANCREATIC ELASTASE I STOOL CONTENT: AN INDEPENDENT RISK FACTOR OF THE OSTEOPOROSIS IN ELDERLY WOMEN

J. Teichmann*, U. Lange, Ph. Hardt, H. Schnell-Kretschmer, H. Stracke, R. G. Bretzel, H. U. Klör

Medizinische Klinik und Poliklinik III, Klinikum der Justus-Liebig-Universität, Giessen, Germany

 
P423 S
RISK STRATIFICATION BY PERIPHERAL BONE MASS: COMPARISON OF RANDOM POPULATION SCREENING AND SELECTION BY CLINICAL RISK FACTORS

D. M. Reid*, R. Hughes, W. Fraser, J. Halsey, A. Adebajo, M. Davie, T. Masud, R. Diaz, E. Kerr, M. Mohammed

University of Aberdeen, Aberdeen, UK; Chertey, Liverpool, Lancaster, Barnsley, UK; Oswestry, Nottingham, UK; Aventis, and Procter & Gamble Pharmaceuticals, UK; Riomed, UK

 
P426 S
ANKLE FRACTURE IS ASSOCIATED WITH NORMAL BONE MINERAL DENSITY BUT DISSOCIATION OF ULTRASOUND PROPERTIES OF BONE

B. M. Ingle*, R. Eastell

University of Sheffield, Sheffield, UK

 
P429 S
MUSCULOSKELETAL DETERMINANTS OF VARIANCE IN THE ASSOCIATION BETWEEN THERAPEUTIC EFFECTS ON DEXA-BMD AND FRACTURE INCIDENCE

J. L. Ferretti*, G. R. Cointry, R. F. Capozza, E. J. Roldan, C. R. Gimenez, R. Capiglioni, J. R. Zanchetta

Rosario University School of Medicine, Rosario, Argentina; IDIM/FIM, Buenos Aires, Argentina

Osteoporosis: Pathophysiology

P432 S
BONE STRUCTURE OF THE ILIAC CREST AND LUMBAR SPINE: A HISTOMORPHOMETRIC STUDY OF ADULT POPULATION IN CROATIA

O. Cvijanovic*, I. Kristofic, J. Spanjol, S. Zoricic, I. Maric, D. Bobinac

Department of Anatomy, University of Rijeka, Rijeka, Croatia

 
P435 S
RELATION BETWEEN BONE MASS AT AGE 36 AND CALCIUM INTAKE AND PHYSICAL ACTIVITY DURING THE 25 FOREGOING YEARS

I. Bakker*, H. C. G. Kemper, J. W. R. Twisk, W. van Mechelen

EMGO Institute, Vrije Universiteit, Amsterdam, The Netherlands

 
P438 S
PHANTOMS FOR DUAL ENERGY X-RAY ABSORPTIOMETRIC MEASUREMENTS OF INFANTS

W. Koo*, M. Hammami, S. Rani

Wayne State University, Detroit, MI, USA

 
P441 S
EFFECTS OF GENDER AND AGE DIFFERENCES ON THE DISTRIBTUION OF BONE CONTENT IN THE THIRD LUMBAR VERTEBRA

K. S. Tsai*, W. C. Cheng

National Taiwan University, Taipei, Taiwan

 
P444 S
BONE MINERAL DENSITY IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS. A CROSS-SECTIONAL STUDY WITH 12-MONTHS FOLLOW-UP

J. Rosa*, V. Tesaø, C. Dostál, J. Zadina, J. Kafková

Institute of Rheumatology, Prague, Czech Republic; I.Clinic of Internal Medicine, General University Hospital, Prague, Czech Republic

 
P447 S
THREE-DIMENSIONAL TRABECULAR MICROSTRUCTURE AND BIOMECHANICAL PROPERTIES IN RATS AND MICE WITH HORMONE REPLACEMENT THERAPY

Y. Jiang*, J. Zhao, H. K. Genant

Osteoporosis and Arthritis Research Group, University of California, San Francisco, USA

 
P450 S
RELATIONSHIP OF THE BONE HISTOMORPHOMERY TO THE LEVELS OF VITAMIN K ANALOGUES IN BONE OF THE TREATMENT WITH PHENYTOIN ALONE AND IN COMBINATION WITH ALFACALCIDOL IN GROWING RATS

K. Onodera*, A. Takahashi, H. Wakabayashi, J. Kamei, H. Furuta

Department of Dental Pharmacology, Okayama University Dental School, Okayama, Japan; Division of Pediatric Dentistry, Department of Lifelong Oral Health Sciences, Tohoku University Graduate School of Dentistry, Sendai, Japan; Department of Biophysical Chemistry, Niigata College of Pharmacy, Niigata, Japan; Department of Pathophysiology & Therapeutics, Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo, Japan

 
P453 S
THE BONE'S DISORDER IN CHILDREN TREATED FOR ASTHMA BRONCHIALE

M. Bayer*, J. Novak, P. Visek, V. Derner

Paediatric Department, Charles University, Prague, Czech Republic; Department of Clinical Immunology and Allergology, Litomysl Hospital, Czech Republic; Institute of Clinical Immunology and Allergology, Hradec Kralove, Czech Republic

 
P456 S
BONE LOSS IN PATIENTS ON CORTICOSTEROID THERAPY: A LONGITUDINAL STUDY - ONE YEAR DATA

A. Stewart*, D. M. Reid

Osteoporosis Research Unit, Dept of Medicine and Therapeutics, University of Aberdeen, Aberdeen, UK

 
P459 S
RAPID NORMALIZATION OF SERUM OSTEOCALCIN LEVELS FOLLOWING TERMINATION OF DEXAMETHASONE TREATMENT IN MONKEYS

R. Brommage*, C. Allison

Wake Forest University, Winston-Salem, USA

 
P462 S
RATIONALE FOR CALCIUM/VITAMIN D-SUPPLEMENTED YOGURTS IN THE ELDERLY

V. Coxam*, N. Gaumet-Meunier, M. J. Davicco, P. Lebecque, M. Brandolini, E. Postaire, J. P. Barlet

INRA - CRNH Clermont-Ferrand 63122, France; Danone Vitapole, Le Plessis Robinson, France

 
P465 S
ALCOHOL ABUSE AND OSTEOPOROSIS

A. Humphries*, F. Alam, P. Kyd, A. Fairney

Imperial College School of Medicine, London, UK; The Max Glatt Alcohol and Drug Dependence Unit, Middlesex, UK

 
P468 S
ADVERSE EFFECTS ON BONE MINERAL DENSITY IN PATIENTS WITH ANOREXIA NERVOSA

M. L. Fernandez-Soto*, M. Quesada, F. J. Gomez, V. Dolz, M. De La Higuera, A. Gonzalez, F. Escobar-Jimenez

Eating Disorders Unit. Endocrine Department. University Hospital San Cecilio

 
P471 S
LOW PHOSPHATE DIET ALTERS MRNA GENE EXPRESSION IN THE HYPOTHALAMO-PITUITARY COMPLEX OF THE RAT

M. H. Meyer*, B. Louie, S. E. Mulroney, M. Levi, R. A. Meyer

Carolinas Medical Center, Charlotte, NC USA; Georgetown Univ. Sch. Med., Washington, DC USA; Univ. Texas Health Sci. Ctr., Dallas, TX USA

 
P474 S
BONE CHANGES IN AROMATASE OVER-EXPRESSING TRANSGENIC MICE

Z. Q. Peng*, X. D. Li, S. Mäkelä, M. Poutanen, H. K. Väänänen

University of Turku, Finland

 
P477 S
THE MSP1 POLYMORPHISM OF COLLAGEN TYPE IALPHA 2 GENE IS NOT RELATED TO THE DEVELOPMENT OF OSTEOPOROSIS IN MEN: PRELIMINARY RESULTS

I. Ros*, L. Alvarez, P. Peris, N. Guañabens, A. Monegal, T. Ferro, F. Pons, D. Cerda, A. Ballesta, J. Muñoz-Gómez

Hospital Clinic, University of Barcelona, Spain

 
P480 S
TRABECULAR BONE MASS AND BONE FORMATION ARE PRESERVED AFTER MECHANICAL UNLOADING IN P53 KNOCKOUT MICE

A. Sakai*, T. Sakata, R. Okazaki, N. Kunugita, T. Norimura, T. Nakamura

Department of Orthopaedic Surgery, University of Occupational and Environmental Health, Kitakyushu, Japan; Department of Radiation Biology and Health, University of Occupational and Environmental Health, Kitakyushu, Japan; Department of Health Information Science, University of Occupational and Environmental Health, Kitakyushu, Japan

 
P483 S
THE EFFECT OF PHYSICAL EXERCISE ON INSULIN LIKE GROWTH-FACTOR AND IGFBP-3 LEVELS IN PATIENTS WITH OSTEOARTHRITIS UND OSTEOPOROSIS

H. Franck*, F. Blum

Rheumazentrum Oberammergau, Germany; University of Tübingen, Germany

 
P486 S
DIFFERENCES OF BONE DENSITY IN ATHLETES AND IN ANOREXIC PATIENTS ADOLESCENT FEMALES

A. Andreoli*, U. Tarantino, N. Candeloro, M. Giampietro, L. Promenzio, A. De Lorenzo

Human Nutrition Unit, University of Rome "Tor Vergata", Rome, Italy; Orthopaedic Department, University of Rome "Tor Vergata", Rome, Italy; Institute of Sport Science, Rome, Italy

 
P489 S
MEASUREMENT OF ULTRASOUND TRANSMISSION VELOCITY ENABLES TO CONSIDER THE MECHANICAL PROPERTIES OF AN OSSEOUS IMPLANTATION SITE

P. H. Kann*, B. Al-Nawas, R. Brahm, J. Vaterrodt, K. A. Grötz, W. Wagner, J. Beyer

Clinic for Internal Medicine/Endocrinology and Metabolic Diseases, Johannes Gutenberg University Hospital, Mainz, Germany; Clinic for Oral and Maxillofacial Surgery, Johannes Gutenberg University Hospital, Mainz, Germany

 
P492 S
URINARY cAMP SUPPRESSION TEST IN OSTEOPOROSIS

R. Tanakol*, M. Akyýldýz, A. Akköse, B. Ömer, S. Yarman

Endocrinology, Istanbul Faculty of Medicine, Istanbul, Turkey; Biochemistry, Istanbul Faculty of Medicine, Istanbul, Turkey

 
P495 S
AMYLIN INHIBITS OSTEOPENIA IN DIABETIC RATS

M. N. Horcajada-Molteni, B. Chanteranne, C. Picherit, P. Lebecque, M. J. Davicco, V. Coxam, A. A. Young, J. P. Barlet*

U3M, INRA Clermont-Theix, 63122 France; Amylin Pharmaceuticals Inc, San Diego, USA

 
P498 S
BONE MASS IN MALE PATIENTS SUFFERING FROM INFLAMATORY BOWEL DISEASE

R. Perez-Cano*, M. A. Vazquez-Gamez, M. J. Gomez-De-Tejada, E. Lopez-Herrero, M. J. Montoya-Garcia, M. L. Castro, R. Moruno-Garcia, M. J. Miranda-Garcia

Department of Internal Medicine, Osteoporosis Unit, University Hospital Virgen Macarena; Digestive Service, University Hospital Virgen Macarena

 
P501 S
DETERMINANTS OF OSTEOBLASTIC FUNCTION AMONG HOSPITALIZED ELDERLY: EVALUATION OF BASAL AND STIMULATED SERUM OSTEOCALCIN

V. Badot*, S. De Breucker, P. Bergmann, T. Pepersack, A. Peretz

CHU Brugmann, Free University of Brussels, Belgium

 
P504 S
THE INTERACTION BETWEEN THE VITAMIN D RECEPTOR GENOTYPES AND LIFESTYLE FACTORS ON BONE MINERAL DENSITY

A. Morita*, Y. Dohi, Y. Ikeda, M. Iki, S. Kagamimori, Y. Kagawa, T. Matsuzaki, H. Yoneshima, F. Marumo

Kinki University School of Medicine, Osaka-Sayama, Japan; Nara Medical University, Kashihara, Japan; JPOS Study Group; President, JPOS Study Group, Tokyo Medical and Dental University, Tokyo, Japan

 
P507 S
HIGH CYSTATIN C IS AN INDICATOR OF DECLINING RENAL FUNCTION AND IS RELATED TO OSTEOPOROSIS IN A LONGITUDINAL POPULATION STUDY

E. Waern*, J. Kanis, A. Lindahl, G. Lindstedt, S. Ljunghall, D. Mellström

Dept of Geriatric Medicine, Göteborg University, Sweden; Dept of Human Metabolism, Sheffield University, UK; Dept of Clinical Chemistry and Transfusion Medicine, Göteborg University, Sweden; AstraZeneca

 
P510 S
THE INFLUENCE OF PREGNANCY AND LACTATION ON OS CALCIS ULTRASONOMETRY IN POSTMENOPAUSAL WOMEN

P. Hadji*, M. Kalder, K. Bock, M. Meyer-Wittkopft, S. Schmidt, K. D. Schulz

Philipps-University of Marburg, Marburg, Germany

 
P513 S
A CASE CONTROL STUDY OF SEX STEROIDS AND BONE TURNOVER IN MEN WITH SYMPTOMATIC VERTEBRAL FRACTURES

S. P. Tuck*, A. C. Scane, R. M. Francis, M. Diver, W. D. Fraser, D. Fatayerji, R. Eastell

Bone Clinic, Freeman Hospital, Newcastle upon Tyne, UK; Royal Liverpool Hospital, Liverpool, UK; Northern general Hospital, Sheffield, UK

 
P516 S
EFFECT OF EARLY MENOPAUSE ON BONE MINERAL DENSITY AND BIOCHEMICAL MARKERS

C. S. Shin*, J. H. Kim, Y. J. Park, S. Y. Kim, J. G. Kim

Dept of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; Dept of Obstetric and Gynecology, Seoul National University College of Medicine, Seoul, Korea

 
P519 S
COMPARISON OF MICROSTRUCTURAL CHANGES AMONG THREE OSTEOPOROTIC RAT MODELS INDUCED BY STEROID, OVARIECTOMY AND SCIATIC NEURECTOMY

M. Ito*, A. Nishida, M. Uetani, K. Hayashi

Department of Radiology, Nagasaki University, Japan

 
P522 S
STRUCTURAL ANALYSIS OF OVARIECTOMIZED MONKEY MANDIBLE USING MICRO CT

S. Ejiri*, M. Tanaka, E. Toyaoka, H. Tsusaki, K. Fukuzaki, H. Miyajima, S. Kohno, H. Ozawa

Niigata University, Dept of Anatomy, Faculty of Dentistry, Niigata, Japan; Niigata University, Dept of Prosthodontics, Faculty of Dentistry, Niigata, Japan; Shin Nippon Biomedical Laboratories Ltd., Dept of the 2nd Safety Research, Kagoshima, Japan

 
P525 S
THE EFFECT OF OVARIECTOMY ON BONE LOSS IN THE EDENTULOUS AND DENTATE MANDIBLE

E. S. Elsubeihi*, M. D. Grynpas, A. M. Cheung, G. A. Zarb, J. N. M. Heersche

Faculty of Dentistry, University of Toronto, Toronto, ON, Canada.; Mount Sinai Hospital, Toronto, ON, Canada.; The Toronto General Hospital, Toronto, ON, Canada

 
P528 S
SKELETAL EFFECTS OF BENZO[A]PYRENE AND RESVERATROL IN ESTROGEN-REPLETED OVARIECTOMIZED RATS

L. Lee, J. Lee, R. F. Casper, J. F. Savouret, M. D. Grynpas*

Samuel Lunenfeld Research Institute, Mount Sinai Hospital; Department of Laboratory Medicine and Pathobiology, University of Toronto; Division of Reproductive Sciences, Mount Sinai Hospital; INSERM Unit 135, Hosp de Bicetre (Le Kremlin-Bicetre)

Osteoporosis: Treatment

P531 S
EFFECT OF ANTIHYPERTENSIVE TREATMENT WITH QUINAPRIL, QUINAPRIL-HYDROCHLOROTHIAZIDE AND ENALAPRIL ON MINERAL BONE DENSITY IN HYPERTENSIVE PATIENTS.PRELIMINARY RESULTS

J. L. Perez-Castrillón*, J. Silva, P. Escudero, R. Igea, I. Justo, M. Martín-Luquero, C. Pueyo, C. Diaz, G. Hernandez, A. Dueñas

Hospital Rio Hortega, Valladolid, Spain; Pfizer, Spain

 
P534 S
STUDY ON CLINICAL EFFECT OF PULSE ELECTROMAGNETIC FIELD TREATMENT

Y. T. Zhao*, C. F. Chen

Bone mineral Unit, Jinan military , General Hospital, Jinan, Shangdong 250031, PR China

 
P537 S
LONG-TERM EXPOSURE TO STRONTIUM RANELATE DOSE-DEPENDENTLY INCREASES BONE STRENGTH IN INTACT FEMALE RATS

P. Ammann*, B. Robin, J. P. Bonjour, I. Tupinon-Mathieu, J. M. Meyer, R. Rizzoli

Div. of Bone Diseases, Dpt. of Int. Med., and School of Dentistry, Univ. Hosp., Geneva, Switzerland; Inst. Recherches Internationales Servier, Courbevoie, France

 
P540 S
CYCLICAL ETIDRONATE THERAPY FOR PREVENTION OF BONE LOSS IN MEN WITH IDIOPATHIC OSTEOPOROSIS: A 1-YEAR STUDY

B. Gerbert*, H. Heinze, J. Schulze

Clinic of Internal Medicine III, University of Dresden, Germany

 
P543 S
ALENDRONATE VERSUS ETIDRONATE FOR OSTEOPENIC PATIENTS WITH PRIMARY BILIARY CIRRHOSIS

N. Guañabens*, A. Parés, I. Ros, F. Pons, L. Alvarez, L. Caballería, A. Monegal, M. Roca, P. Peris, J. Rodés

Metabolic Bone Diseases Unit, Hospital Clínic, IDIBAPS, University of Barcelona, Spain; Liver Unit, Hospital Clínic, IDIBAPS, University of Barcelona, Spain; Department of Pharmacy, Hospital Clínic, University of Barcelona, Spain

 
P546 S
FOLLOW-UP ENDOSCOPY STUDY COMPARING RISEDRONATE AND ALENDRONATE IN POSTMENOPAUSAL WOMEN STRATIFIED BY H. PYLORI STATUS

A. B. R. Thomson*, J. K. Marshall, R. H. Hunt, F. L. Lanza, M. A. Blank

University of Alberta, Edmonton, AB, Canada; McMaster University, Hamilton, ON, Canada; Houston Institute for Clinical Research, Houston, TX, USA; Procter & Gamble Pharmaceuticals, Mason, OH, USA

 
P549 S
EFFECT OF ALENDRONATE (ALE) AFTER SUCCESSFUL CYCLICAL ETIDRONATE (ICE) THERAPY IN OSTEOPOROTIC WOMEN

D. S. Ooi*, A. B. Cranney, M. Murdock, J. D. Gay

Ottawa Hospital Civic Campus, Ottawa, Canada

 
P552 S
COMPARISON OF THE EFFECTIVENESS OF HORMONE REPLACEMENT THERAPY, BISPHOSPHONATE, CALCITONIN, VITAMIN D, AND VITAMIN K IN POSTMENOPAUSAL OSTEOPOROSIS: A ONE-YEAR PROSPECTIVE, RANDOMIZED, CONTROLLED TRIAL

Y. Ishida*, H. Soh, M. Tsuchida, S. Kawahara, H. Murata

Yamaguchi University School of Medicine, Yamaguchi, Japan; Tsushimi Hospital, Yamaguchi, Japan

 
P555 S
EFFECT OF ENZYME THERAPY AND COMBINATION THERAPY WITH ALENDRONATE ON THE OVARIECTOMIZED RATS

K. Svik*, E. Rovenska, M. Stancikova, R. Istok, J. Rovensky, Z. Veselkova

Research Institute of Rheumatic Diseases, Piestany, Slovakia

 
P558 S
RISEDRONATE REDUCES THE RISK OF CLINICAL VERTEBRAL FRACTURES BY 1 YEAR

D. M. Reid*, R. Eastell, C. Roux, C. Kasibhatla

Aberdeen Royal Infirmary, Aberdeen, UK; University of Sheffield, Sheffield, UK; Rene Descartes University, Paris, France; Procter & Gamble Pharmaceuticals, Mason, OH, USA

 
P561 S
RSAI POLIMORPHISM OF ER-BETA GENE AND ALENDRONATE TREATMENT OF OSTEOPORORSIS

J. Marc*, B. Arko, J. Prezelj, A. Kocijanèiè

Faculty of Pharmacy, Univ. of Ljubljana, Ljubljana, Slovenia; Dept. of Endocrinology and Metabolic Diseases, Clinical center, Ljubljana, Slovenia

 
P564 S
BISPHOSPHONATES AND UPPER GI PROBLEMS - WHAT IS THE EVIDENCE?

B. Cryer*, D. C. Bauer

University of Texas Southwestern, Dallas, TX, USA; University of California, San Francisco, CA, USA

 
P567 S
HRT AND VARIOUS DOSES OF PAMIDRONATE IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS: ADDITIVE EFFECT ON BONE RESORPTION, NOT ON BONE FORMATION

L. Sandini*, O. Lamy, S. Fatio, I. Pache, P. Burckhardt

Department of Internal Medicine, Lausanne University Hospital, Switzerland

 
P570 S
RISEDRONATE IS EFFECTIVE IN PREVENTING FIRST VERTEBRAL FRACTURE IN WOMEN

I. Fogelman*, C. Ribot, J. Glowinski, R. Crozier

Guy's Hospital, London, UK; Hopital Rangueil, Toulouse, France; Centre Hostitalier, Gonesse, France; Procter & Gamble Pharmaceuticals, Geneva, Switzerland

 
P573 S
TREATMENT OF GLUCOCORTICOSTEROID-INDUCED OSTEOPOROSIS IN MALE RATS: HISTOMORPHOMETRIC ANALYSIS BETWEEN ALENDRONATE AND FLUORIDE

E. B. Dourador*, V. Falco, R. A. Souza, B. Luna Filho, E. D. Bonfa, V. Jorgetti

Faculty of Medicine - Sao Paulo University, Brazil; Paulista Medical School - Federal University, Sao Paulo, Brazil

 
P576 S
THE EFFECT OF ALENDRONATE ON AGE-SPECIFIC INCIDENCE OF KEY OSTEOPOROTIC FRACTURES

M. C. Hochberg*, D. E. Thompson, D. Black

University of Maryland, USA; Merck & Co, USA; University of California, San Francisco, USA

 
P579 S
EFFECT OF INTRANASAL SALMON CALCITONIN ON BONE MARKERS IN MEN WITH IDIOPATHIC OSTEOPOROSIS

G. Trovas*, G. Lyritis, E. Constantelou, J. Koulouris

University of Athens, Laboratory for Research of Musculoskeletal System "Th.Garofalidis", Athens, Greece; Hormonological Laboratory of Public Hospital, Saint Panteleimonas, Piraeus, Greece

 
(P582 transferred to the Thursday poster session)

 
P585 S
COMPARISON OF THE EFFECT OF COMBINED CALCIUM-VITAMIN D OR CALCIUM ALONE ADMINISTRATION ON CIRCULATING LEVELS OF PARATHYROID HORMONE (PTH) AND 25-OH VITAMIN D (25-OHD) IN AMBULATORY VITAMIN D-DEPLETED POST-MENOPAUSAL WOMEN

R. Deroisy*, J. Collette, A. N. Taquet, Fr Thines, J. Y. Reginster

WHO Collaborating Center of Public Aspects of Rheumatic Disorders, including Osteoporosis, Liège, Belgium; Bone and Cartilage Metabolism Unit, University of Liège, Liège, Belgium; WILL-PHARMA, Belgium

 
P588 S
THE MAGNITUDE OF THE PTH RESPONSE TO CALCIUM SUPPLEMENTATION

R. P. Heaney, M. S. Dowell, J. Bierman, C. A. Hale, A. Bendich*

Creighton University, Omaha, NB, USA; SmithKline Beecham Consumer Healthcare, Parsippany, NJ, USA

 
P591 S
BONE TURNOVER IN SMOKING AND NON-SMOKING POSTMENOPAUSAL FEMALES BEFORE AND DURING ESTROGEN REPLACEMENT THERAPY

R. K. Tahtela*, S. Sairanen, K. Laitinen, E. Hirvonen, J. Risteli, M. J. Valimaki

Leiras Oy, Clinical Research, Helsinki, Finland; Helsinki University Hospital, Division of Endocrinology, Helsinki, Finland; Helsinki Medical Center, Helsinki, Finland; Oulu University Hospital, Dpt of Clinical Chemistry, Oulu, Finland

 
P594 S
LASOFOXIFENE INHIBITS BONE TURNOVER AND MAINTAINS SPINE BMD AFTER OVARIECTOMY IN MONKEYS

R. Brommage*, C. E. Hotchkiss, M. W. Stancill, C. J. Lees

Wake Forest University, Winston-Salem, USA

 
P597 S
PROGRESSIVE RESPONSE OF SERUM BETA-CROSSLAPS TO SUBCUTANEOUS ESTRADIOL IMPLANT

A. C. Eagleton*, C. A. Pereda, R. A. Hannon, K. E. Naylor, A. Blumsohn, R. Eastell

Bone Metabolism Group, University of Sheffield, UK

 
P600 S
RALOXIFENE PREVENTS URINARY CALCUM LOSS IN LATE POSTMENOPAUSAL WOMEN

J. R. Talbot, A. Marino, J. Zanchetta, G. Martinez, M. Moran*, O. D. Messina

River Plate University, School of Medicine, Argentina; Osteology Master Program. USAL School of Medicine, Argentina; Rheumatology & Osteolgy Research Institute, Argentina

 
P603 S
BRIEF HOME ISOMETRIC RESISTIVE EXERCISE STRENGTHENS BACK EXTENSOR MUSCLES IN OSTEOPOROSIS PATIENTS

R. L. Swezey*, A. M. Swezey

Osteoporosis Prevention & Treatment Center, Santa Monica, USA

 
P606 S
PREVENTIVE EFFECTS OF CHINESE HERBAL PREPARATION ON DEVELOPMENT OF OSTEOPOROSIS INDUCED BY OVARIECTOMY IN RATS

P. C. Leung, Y. Y. Shi, H. B. Lu, G. Zhang, Y. W. Hung, Y. F. Chao, S. C. Fu, L. Qin*

Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China; Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong SAR, PR China; Suguang Hospital, Shanghai University of Chinese Medicine, PR China

 
P609 S
PREDICTORS OF BONE MASS VARIATION IN ALENDRONATE TREATMENT OF OSTEOPOROSIS IN YOUNG PATIENTS

M. L. Bianchi*, R. Cimaz, M. Gattorno, A. Dubini, M. Bardare, F. Zulian, F. Falcini, L. Lepore, A. Boncompagni

Istituto Auxologico Italiano, Milano; Clinica Pediatrica Università di Milano; Istituto Gaslini, Genova; Clinica Pediatrica Università di Padova; Clinica Pediatrica Università di Firenze; Istituto Burlo Garofolo, Trieste

 
P612 S
SEX-BIAS IN REFERRAL FOR BONE DENSITOMETRY

M. A. Kotowicz*, B. Sarah, J. A. Pasco, M. J. Henry, K. M. Sanders, S. Korn, G. C. Nicholson

University of Melbourne, Geelong, Victoria, Australia

 
P615 S
EFFECT ON BONE MARKERS OF THREE MONTHLY 2MG INTRAVENOUS IBANDRONATE: 2 YEARS OF TREATMENT AND ONE YEAR AFTER WITHDRAWAL

O. Lamy*, I. Pache, S. Fatio, A. F. Jaquet, P. Burckhardt

University Hospital, Lausanne, Switzerland

 
P618 S
ADHERENCE TO OSTEOPOROSIS THERAPIES

J. Finigan*, P. R. Bainbridge, R. Eastell

University of Sheffield Division of Clinical Sciences, Northern General Hospital, Sheffield, S5 7AU, UK

 
P621 S
A CLINICAL PATHWAY FOR A TARGETED MEDICAL MANAGEMENT OF PATIENTS WITH A RECENT OSTEOPOROTIC FRACTURE

T. Chevalley*, P. Hoffmeyer, J. P. Bonjour, R. Rizzoli

Division of Bone Diseases, Department of Internal Medicine, University Hospital, Geneva, Switzerland; Unit of Geriatric Evaluation, Department of Geriatrics; Orthopedic Clinic, Department of Surgery

 
P624 S
ANABOLIC EFFECTS OF H-PTH (1-34) ON CORTICAL BONE IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

T. Tsuchida*, N. Miyakoshi, Y. Kasukawa, Y. Tamura, K. Suzuki, A. Seki, K. Sato

Dept. of Orthopedic Surgery, Akita University, Akita, Japan; Mitsubishi Chemical Safety institute, LTD, Kashima, Japan; Dept. of Orthopedic Surgery, Koto General Hospital, Akita, Japan

 
P627 S
LOW BONE MINERAL DENSITY AS AN INDEPENDENT DETERMINANT OF THE FUNCTIONAL RECOVERY IN ELDERLY HIP-FRACTURED WOMEN

M. Di Monaco*, R. Di Monaco, M. Manca, A. Cavanna

Presidio Sanitario San Camillo, Torino, Italy; IRES Lucia Morosini, Torino, Italy

 
P630 S
A RANDOMISED TRIAL OF A MODIFIED VERSION OF THE SF12 FOR USE IN QUALITY OF LIFE MEASUREMENT IN OSTEOPOROSIS STUDIES

D. J. Torgerson*, C. P. Iglesias, Y. F. Birks

University of York, UK

 
P633 S
ALFACALCIDOL IMPROVES BONE STRENGTH BY STIMULATING BONE FORMATION AND SUPPRESSING RESORPTION: COMPARATIVE STUDIES WITH VITAMIN K2

A. Shiraishi*, S. Higashi, T. Masaki, Y. Uchida, M. Saito, M. Ito, S. Ikeda, T. Nakamura

Chugai Pharmaceutical Co, Ltd., Tokyo, Japan; Nagasaki University, Nagasaki, Japan; University of Occupational and Environmental Health School of Medicine, Kitakyushu, Japan

 
P636 S
INCREASE IN FEMORAL BONE STRENGTH BY THE TREATMENT WITH ALFACALCIDOL BUT NOT WITH PLAIN VITAMIN D

S. Higashi*, T. Masaki, A. Shiraishi, Y. Uchida, M. Saito, E. Ogata, T. Nakamura

Chugai Pharmaceutical Co. Ltd., Tokyo, Japan; Cancer Institute Hospital, Tokyo, Japan; University of Occupational and Environmental Health, Fukuoka, Japan

 
P639 S
ALFACALCIDOL INHIBITS BONE RESORPTION, MODULATES CYTOKINES AND REDUCES PAIN IN PATIENTS WITH RHEUMATOID ARTHRITIS AND OSTEOPENIA

S. H. Scharla*, S. Bawey, D. Holle, J. Boensch, I. Kamilli, E. Quade, C. Loeffel, U. G. Lempert

Klinikum Berchtesgadener Land, Schoenau am Koenigssee, Germany

 
P642 S
EFFECT OF DAILY REGIMEN ADMINISTRATION OF CALCIUM-VITAMIN D SUPPLEMENTS ON DECREASE OF PARATHYROID HORMONE LEVELS

J. Y. Reginster*, B. Zegels, E. Lejeune, A. N. Taquet, M. C. Micheletti, A. Albert

1. Bone and Cartilage Research Unit, University of Liège, Liège, Belgium; 2. WHO Collaborating Center on Public Health Aspects of Rheumatic Disorders, Liège, Belgium; 3. Medical Department, Laboratoire Theramex, Monaco; 4. Department of Medical Informatics, University of Liège, Liège, Belgium

Vitamin D

P645 S
DECREASED SEASONAL VARIATION IN VITAMIN D LEVELS IN MEDICAL OUTPATIENTS IN MIAMI, FLORIDA (UNITED STATES)

S. Levis*, A. Gomez, C. Jimenez, L. S. Veras, B. W. Hollis, S. Lai, B. A. Roos

University of Miami School of Medicine, GRECC/VA Medical Center, State of Florida Teaching Nursing Home at Miami Jewish Home & Hospital for the Aged, Miami, FL, USA; Jackson Memorial Hospital/University of Miami School of Medicine/VA Medical Center, Miami, FL, USA; Medical University of South Carolina, Charleston, SC, USA; Johns Hopkins University, Baltimore, MD, and State of Florida Teaching Nursing Home at Miami Jewish Home & Hospital for the Aged, Miami, FL, USA

 
P648 S
TARGETED ABLATION OF THE 25-HYDROXYVITAMIN D-1-ALPHA-HYDROXYLASE: AN ANIMAL MODEL OF PSEUDO VITAMIN D DEFICIENCY RICKETS

O. Dardenne*, J. Prud'homme, A. Arabian, F. H. Glorieux, R. St-Arnaud

Genetics Unit, Shriners Hospital for Children and Depts. of Surgery and Human Genetics, McGill University, Montreal, Quebec, Canada

 
P651 S
A LOW CALCIUM DIET INCREASES PLASMA MEMBRANE CA - ATPASE AND SODIUM/CALCIUM EXCHANGER ACTIVITIES FROM CHICK ENTEROCYTES

V. Centeno*, A. Alisio, N. Tolosa de Talamoni

Laboratorio de Metabolismo Fosfocálcico y Vitamina D "Dr. Cañas", Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina

 
P654 S
TUMOR NECROSIS FACTOR ALPHA GENE TRANSCRIPTION IS REPRESSED BY THE VITAMIN D₃ RECEPTOR-MEDIATED INTERACTION WITH THE KAPPA3 ELEMENT IN THE PROMOTER REGION

A. Takeuchi*, M. Yoshikawa, T. Yoshizawa, S. Kato, S. Sharma, T. Okano

Kobe Pharmaceutical University, Kobe, Japan; Institute of Molecular and Cellular Bioscience, The University of Tokyo, Tokyo, Japan; Women and Infant' Hospital, Brown University, Providence, USA

Late Poster (unclassified, and not subjected to full review by the Scientific Program Committees)

P657 S
Withdrawn

 
P660 S
EFFECT OF ADVANCED GLYCOSYLATION END-PRODUCTS ON THE PROLIFERATION AND DIFFERENTIATION OF RAT'S OSTEOBLASTIC CELL

Kong Dejuan*, Li En, Li Shanglie, Li Tao, Chen Yongchun, Li Fangfang

Dept of Biochemistry, HeBei Medical University, Shijiazhuang 050017, P. R. China

 
P663 S
EFFECT OF NSAIDS ON AMINOPEPTIDASE ACTIVITIES IN HUMAN OSTEOBLASTS

C. Reyes-Botella*, G. Lucena2, F. Alba, C. Ruiz

Departamento de Estomatología. Facultad de Odontología

Departamento de Bioquimica y Biología Molecular. Facultad de Medicina

Departamento de Enfermería. Escuela Universitaria Ciencias de la Salud, Universidad de Granada

 
P666 S
BONE MINERAL DENSITY IN MEN WITH APPENDICULAR FRACTURESE

Vega, M. Belotti, C. Gómez Acotto, C. Merlo, L. Poitevin, C. Mautalen

Sección Osteopatías Médicas y División Traumatología y Ortopedia, Hospital de Clínicas, Buenos Aires, Argentina

 
P669 S

SERUM CTX IN RENAL PATIENTS: A LONGITUDINAL STUDY

A Wittich, C. Casco, A. Oviedo, S. Zeni, M. Nadal, C. Mautalen

Sección Osteopatías Médicas and Servicio de Nefrología, Hospital de Clínicas, Universidad de Buenos Aires, Argentina

 
P672 S

THE EFFECTS OF YIGU ZHUANGGU TANG ON BONE MINERAL DENSITY IN PATIENTS WITH GLOMERULAR NEPHRITIS

Liu Baoyu

Beijing Chao Yang Hospital, Affiliate of Capital University of Medical Sciences, Beijing, 100020, P. R. China

 
P675 S

THE EFFECTS OF THE FRACTURE-HEALING STIMULI (JIN PU YE) ON OSTEOBLASTS IN VITRO

Zhu Jian-min*, Fang Hao, Chen Xin-gan, Jin Weifang, Wang Hongfu

Department of Orthopedics, Shanghai 8th Hospital, Shanghai-200233, P. R. China

[Saturday at a Glance] [Contents page]