Meet the Professor Sessions

Gregor Adams (Los Angeles, USA)

Bone and bone marrow hematopoiesis

Topics to be covered

• The location of the hematopoietic stem cells within the bone marrow
• The role of osteoblasts and osteoclasts in the hematopoietic stem cell niche
• Spatial differences in niche regulation of hematopoietic stem cells between different sites of bone marrow hematopoiesis
• Therapeutic targets for hematopoietic stem cell based therapies

Educational goals

After attending this Meet the Professor session, participants will be expected to:

• understand the key determinants defining the stem cells niche
• understand the relationship between bone or bone remodelling and bone marrow hematopoiesis
• define the key mechanisms involved in hematopoietic stem cell self-renewal
• identify potential therapeutic targets within the hematopoietic stem cell niche

Target audience

• Graduate students and post-doctoral research fellows interested in hematopoietic stem cell research

Teaching methods

• A round-table discussion with handouts