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PhD Training Course - LJUBLJANA
1-4 September 2011
City Hotel, Ljubljana, Slovenia
http://www.cityhotel.si
REGISTRATION
FOR
THIS
COURSE
IS
NOW
CLOSED
If
you
would
like
to
be
added
to
the
reserve
list
for
2011,
or
are
interested
in
participating
in
next
years’
PhD
training
course
please
send
an
email
to
exec@ectsoc.org
 An updated programme, student abstracts and speaker notes (password protected) are now available to registered students and ECTS members
Aims
and
Learning
Outcomes
Programme
Speaker notes (password protected)
Venue
Registration
details
Announcement [PDF]
AIMS AND LEARNING OUTCOMES
Aims:
- To increase knowledge about physiology and pathology of mineralized tissues
- To disseminate knowledge about key methods in bone research
- To promote networking between PhD students in the bone field
Learning Outcomes:
At the end of the course, the PhD student should:
- Have a greater understanding of bone biology, bone metabolism, and a range of important primary and secondary bone diseases
- Understand the similarities and differences between various mineralized tissues
- Have knowledge of clinical treatments used in bone diseases
- Be familiar with histology and anatomy of bone tissue, its innervations and vascularisation
- Be able to present and discuss their own PhD project and critically appraise projects of fellow students
Registration fees:
€250 (includes meals as specified and shared accommodation)
or
€350 (includes meals as specified and single accommodation)
PROGRAMME
THURSDAY September 1st
Introduction, setting the scene
Chair: Miep Helfrich
13.45 Introduction to the course, programme outline - Miep Helfrich, Aberdeen, UK
14.00 Bone, tissue and microscopical structure - Miep Helfrich, Aberdeen, UK
14.30 Osteoclasts, and how to study them - Tim Arnett, London, UK
15.00 Osteoblasts, and how to study them - Christa Maes, Leuven, BE
15.30 Osteocytes, and how to study them - Astrid Bakker, Amsterdam, NL
16.00 Coffee break
16.30 Bone metabolism and calciotropic hormones - Mark Cooper, Birmingham, UK
17.15 Osteoporosis, disease and genetic predisposition - Janja Marc, Ljubljana, SI
18.00 End of scientific programme
18.30 Guided boat tour of Ljubljana (meet in hotel lobby at 18.15)
20.00 Dinner
FRIDAY September 2nd
Session 1 Bone innervation, vascularisation and pain
Chair: Mark Cooper
08.30 Bone vascularisation and innervations -Chantal Chenu, London, UK
09.15 Studies of bone pain - Anne- Marie Heegard, Copenhagen, DK
10.00 Controversies around mechanisms of bone pain -Tim Arnett, London, UK
10.15 Coffee break
Session 2 Pharmacology of osteoporosis
Chair: Anne-Marie Heegard
10.45 Antiresorptive therapies - Bo Abrahamsen, Odense , DK
11.15 Anabolic therapies - Mark Cooper, Birmingham, UK
11.45 Biomarkers old and new -Pawel Szulc, Lyon, FR
12.15 Lunch
13.15 Student presentations
2 parallel sessions with 22 students per room
First year students - 5 minutes + 3 minutes discussion
Room 1 - Clinical and genetic studies
Chair: Janez Preželj, Ljubljana
1. Reedik Pääsuke - The role of disorders of energy metabolism in mechanisms of aging-related muscular weakness sarcopenia: cell biological and clinical aspects
2. Barbara Rubek Nielsen - Ageing and Bones - Does age, assessed biologically and genetically, correlate to measures of bone mineral density?
3. Olivia Trummer - Steroid hormones and pharmacogenetics using the example of vitamin D
4. Peter Vrtacnik - DNA methylation analysis of osteoporotic and osteoartritic bone tissue
5. Igor Fijalkowski - Genetic and functional study of the effect of sclerostin-binding proteins on bone anabolism
6. Jean Redmond -Ethnic differences in bone and kidney metabolism
7. Inês Perpétuo - Differences in osteoclastic activity between rheumatoid arthritis and ankylosing spondylitis
Room 2 - Cell and signalling studies
Chair: Christa Maes
1. Allahdad Zarei - Differential osteoblastic activities of vitamins D2 and D3
2. Asim Khogeer - Effect of genetic and pharmacological intervention of RANK receptor on the development and progression of cancer associated bone disease
3. Margaret Davis - The role of fibrillin-1 and other extracellular matrix proteins in the function and differentiation of mesenchymal cell types.
4. Jordi Caballe Serano; -3D osteogenesis through the use of Dental Pulp Pluripotent Stem Cells
5. Jennifer Thomson - Expression and characterisation of recombinant human TSG-6, a potential therapeutic for bone diseases
6. Torben Madsen Kvist - bone loss in autoimmune disease - is p2x7 involved
14.15 General poster viewing,
Presenters to be at their poster for the first 20 minutes, then free to move around; structured discussion will follow on Saturday
15.15 Coffee/Tea break
Session 3 Techniques
Chair: Astrid Bakker
15.45 Micro RNAs -Vid Mlakar, Ljubljana, SI
16.30 Transfection techniques for bone cells - Julie Crockett, Aberdeen, UK
17.15 End scientific programme
18.00 Dinner
SATURDAY September 3rd
Session 4 Mineralised tissues other than bone
Chair: Tim Arnett
8.30 Bones and teeth: similarities, differences and interrelation - Françoise Bleicher, Lyon, FR
9.15 Vascular calcification - Patrick D'Haese, Antwerp, BE
10.00 Coffee break
Session 5 Maintenance of bone mass
Chair: Karl Michaelsson
10.30 Role of oestrogen -Marie Lagerquist, Gotenburg, SE
11.15 Role of feeding - Jennifer Walsh, Sheffield, UK
12.00 Lunch
13.00 Student presentations
2 parallel sessions - 22 students per room,
Final year students - 8 minutes + 4 minutes discussion
Room 1 Clinical and translational studies
Chair: Bo Abrahamsen
1. Eetu Heerva - Bone health in neurofibromatosis 1
2. Carole Le Henaff - CFTR: Engaging and therapeutic target in osteoporosis
3. Andy Kin On Wong - Comparison of hr-pQCT, pQCT and MRI for quantifying bone structure and their associated relation to fractures
4. Greetje Renders - Consequences of interaction between cartilage and bone for development of osteoarthritis
5. Jovana Kaludjerovic - Early life exposure to soy isoflavones, combined with folate, favorably program bone metabolism in a female mouse model
6. Vaidile Strazdiene - Relationship between Vitamin D and cardiometabolic risk factors among community dwelling persons
7. Asta Mastaviciute - Relationship between body composition and bone turnover markers in community dwelling very old men
Room 2 Cellular and Signalling studies
Chair: Julie Crockett
1. Heiani Touaitahuata - Role of osteoclasts degradation activity during endochondral bone formation
2. Janja Zupan - The Influence Of Pro-Inflammatory Cytokines On Rank/Rankl/Opg System In Human Bone Tissue In Osteoporotic And Osteoarthritic Patients
3. Deepak Balani - Effect of inflammatory cytokines in osteoclastogenesis
4. Tristan Fowler; Molecular Mechanisms Mediating the Suppressive Effects of Inhibin on Osteoclastogenesis
5. Edgardo Rodriguez Carballo - Crosstalk between BMP and Wnt signalling at the gene promoter level.
6. Hermann Agis - Prolyl hydroxylase inhibitors increase the pro-angiogenic capacity of periodontal cells while decreasing their catabolic activity
7. Jana Dragojevič - Adipogenesis And Lipotoxicity In Bone Tissue In Osteoporosis
8. Hannah Brown - Elucidating the cellular interactions of early breast tumour growth in bone – an effective target for combination treatment?
14.45 Coffee/Tea break
15.10 Structured poster discussions
4 parallel groups, 11 students per group
3 minutes plus 5 minutes discussion per poster
Group 1 Pharmacology/Biomarkers
Discussion leader: Tomaz Kocjan
1. Sylvia Thiele - Anti-inflammatory and bone-sparing potential of compound A, a selective glucocorticoid receptor modulator
2. Benjamin Sinder - Sclerostin antibody as a treatment in pediatric and adult Brtl/+ models of Osteogenesis imperfecta
3. Verena Maria Schwetz -Biomarker profiling in mother-daughter pairs
Group 2 Signalling studies
Discussion Leader - Aline Bozec
1. Ana Lopez Herradon - Parathyroid hormone-related protein counteracts the inhibitory effect of diabetes mellitus by targeting the canonical Wnt pathway in osteoblasts
2. Simona Bolamperti - Post receptor interactions between 17 beta-estradiol and GH in bone cells
3. Mark Hajjawi - Purinergic signalling and the regulation of bone cell function.
4. Julia Warren - Engineering the RANKL/RANK/OPG Axis for Osteoclast Formation and Function: Mutation-based Insights into Receptor Specificity
Group 3 Clinical studies
Discussion Leader: Maria Luisa Bianchi
1. Carina Cardemil - Clinical and experimental studies on factors influencing bone remodelling
2. Barbara Hauser - Role of autoantibodies in the pathogenesis of osteoporosis in rheumatic diseases
3. Amy Evans - The effects of obesity on bone structure and strength
4. Marta Maycas - Interaction of diabetes mellitus with the parathyroid hormone PTH-related protein/PTH receptor 1 system and the Wnt/beta-catenin pathway in osteocytes.
Group 4 Cellular studies
Discussion Leader: Patrick D'Haese
1. Dongxing Zhu - The appearance and modulation of osteocyte marker expression during calcification of bascular smooth muscle cells
2. Yueyuan Hu - Differentiation of osteoblast precursor cells under simulated space radiation conditions
3. Jacqueline Nguyen - Molecular Mechanisms of Load-induced Bone Formation: a Novel Role for TGFbeta in the Regulation of the Wnt Antagonist Sclerostin
4. María Permuy - Effects of slow action drugs on the cartilage and subchondral bone in a rabbit model of osteoarthritis.
Session 6 Fractures and prevention
Chair: Jennifer Walsh
15.45 Falls and fractures, epidemiology and genetics - Karl Michaelsson, Uppsala, SE
16.30 Exercise is good for the skeleton; what is the evidence? - Harri Sievänen, Tampere, FI
17.00 Short break
17.15 Selling your science, group discussion, presentations after dinner
18.30 Dinner
20.00 SELLING YOUR SCIENCE PRESENTATIONS, Panel members to be announced, all students and tutors to vote
SUNDAY September 4th
Session 7 Methodologies
Chair: Chantal Chenu
9.30 Studying the effects of transcription factors on bone, studies on Fra-2 - Aline Bozec, Madrid, ES
10.15 Clinical trials, past and future - Bo Abrahamsen, Odense, DK
11.00 Coffee/tea break
Session 8 Secondary bone disease
Chair: Harri Sievanen
11.30 Thyroid disease and bone - Tomaz Kocjan, Ljubljana, SI
12.15 Bowel inflammatory disease and bone - Maria Luisa Bianchi, Milan, IT
13.00 Lunch
14.00 Depart
VENUE
The course and accommodation will be at the City Hotel, Ljubljana. Full details can be viewed at http://www.cityhotel.si
Ljubljana is a fascinating city having all the facilities of a modern capital, and yet it has preserved its small-town friendliness and relaxed atmosphere. It is a vibrant city full of surprises. During summer it has a relaxed Mediterranean feel offering natural beauty, cultural sights bearing witness to the city's dynamic history, attractive walking, running and cycling trails, and a diverse range of places to satisfy culinary desires.
Ljubljana Jože Pučnik Airport, located in Brnik near Ljubljana, is the country's main airport and is a 20 minute ride away from the city. Cheap flights to Slovenia are offered by the budget airline Easyjet. Ljubljana is also close to several other airports served by various budget airlines such as Klagenfurt, Trieste, Venice or Rijeka.
Further details available at http://www.visitljubljana.si/
REGISTRATION
Registration
is
now
closed.
Registration fees:
€250 (includes meals as specified and shared accommodation)
or
€350 (includes meals as specified and single accommodation)
NB – places are allocated on a first-come basis to students satisfying the criteria below
Eligibility to attend
• PhD student
• Member of ECTS
• PhD project must involve research in the field of bone or calcium metabolism
PhD students will be required to prepare either a short oral or poster presentation. After registration, the organizers will inform students on their presentation method.
The registration fee of €250 (or €350 for a single room) includes bed and breakfast from Thursday 1 September to Sunday 4 September (3 nights) lunch from Friday 2 September to Sunday 4 September (3 lunches), and evening dinner from Thursday 1 September to Saturday 3 September (3 dinners). As the course is heavily subsidised by the ECTS, there is no reduced fee for those who do not require accommodation or meals.
Thursday 1 September 2011
Arrival, registration, sessions (from 14.00), dinner and overnight accommodation
Friday 2 September 2011
Sessions (08.30-17.00), lunch, dinner and overnight accommodation
Saturday 3 September 2011
Sessions (08.30-17.30), lunch, dinner and overnight accommodation
Sunday 4 September 2011
Sessions (08.30-13.00) lunch, depart
Cancellations and Refunds
Full payment is required when registering on the course. Your place is not guaranteed unless payment has been received.
Any cancellation must be made in writing and sent to admin@ectsoc.org
Cancellations received by 8 July 2011 will be refunded less an administration fee of €35,00. No refunds will be made after this date.
Contact Details
ECTS ,PO Box 337, Patchway, Bristol, BS32 4ZR, UK
Tel: +44 (0)1454 610255
Fax: +44 (0)1454 610255
Email: admin@ectsoc.org
Web: www.ectsoc.org
European Calcified Tissue Society
Registered Charity Number SC033201
Registered Company Number SC220522 |
