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Outline programme [PDF]

Abstracts available here

Invited speaker abstracts

Wednesday 28 May, 2008
10:00-
11:36
HOT TOPICS
Chairs:
Jorge Cannata (Oviedo, Spain)
Richard Eastell (Sheffield, UK)
10:00 OC36 EFFICACY OF DENOSUMAB ON BONE MINERAL DENSITY IN POSTMENOPAUSAL WOMEN WITH LOW BONE MASS AND PATIENTS WITH BREAST CANCER ON ADJUVANT AROMATASE INHIBITOR (AI) THERAPY
H. G. Bone*1, G. Ellis2, C. K. Yuen3, D. L. Kendler4, M. Fan5, H. Wang5, D. Kim5, Y. Liu5, R. Dansey5, J. San Martin5
1Michigan Bone and Mineral Clinic, Detroit, MI, 2Seattle Cancer Care Alliance, Seattle, WA, United States, 3Univ of Manitoba, Winnipeg, 4Univ of British Columbia, Vancouver, Canada, 5Amgen Inc., Thousand Oaks, CA, United States
10:12 OC37 A NOVEL LUNG CANCER SIGNATURE MEDIATES METASTATIC BONE COLONIZATION BY A DUAL OSTEOLYTIC AND METALLOPROTEOLYTIC MECHANISM
D. Luis-Ravelo*1, S. Vicent1, I. Antón1, I. García-Tuñón1, S. Martínez1, C. Zandueta1, J. De Las Rivas2, F. Lecanda1
1Division of Oncology, Center for Applied Medical Research, Pamplona, 2Bioinformatics and Functional Genomics, Cancer Research Center, University of Salamanca, Salamanca, Spain
10:24 OC38 GENOME-WIDE ASSOCIATION STUDY IDENTIFIES KLOTHO AND OTHER NOVEL LOCI AS CONTRIBUTORS TO BMD VARIATION IN POSTMENOPAUSAL WOMEN
E. L. Duncan*1, F. Rivadeneira2, A. Sims1, A. Dowling1, T. Doan1, P. P. Arp3, M. Jhamai3, M. Moorhouse3, D. Evans4, J. Eisman5, G. Jones6, G. Nicholson7, R. Prince8, E. Seeman9, J. A. H. Wass10, A. Hofman11, H. A. Pols2, M. A. Brown1, A. G. Uitterlinden2
1Musculoskeletal Genetics Group, Diamantina Institute, University of Queensland, Brisbane, Australia, 2Department of Internal Medicine and Department of Epidemiology & Biostatistics, 3Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands, 4Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, 5Garvan Institute of Medical Research, University of New South Wales, Sydney, 6Menzies Research Institute, University of Tasmania, Hobart, 7Department of Clinical and Biomedical Sciences, University of Melbourne, Geelong, 8School of Medicine and Pharmacology, University of Western Australia, Perth, 9Departments of Medicine and Endocrinology, Austin Health, University of Melbourne, Melbourne, Australia, 10Metabolic Bone Unit, Nuffield Orthopaedic Centre, Oxford, United Kingdom, 11Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, Netherlands
10:36 OC39 MICRORNAS CONTROL BONE FORMATION IN VIVO AND OSTEOBLAST DIFFERENTIATION EX VIVO
T. Gaur1, R. Mudhasani1, Z. Li1, A. J. van Wijnen1, J. L. Stein1, C. M. Croce2, G. S. Stein1, S. N. Jones1, J. B. Lian*1
1Department of Cell Biology, University of Massachusetts Medical School, Worcester, 2Department of Molecular Virology, Immunology, and Medical Genetics and Comprehensive Cancer Center, Ohio State University, Columbus, United States
10:48 OC40 EXPRESSION OF TRUNCATED ACTIVATOR PROTEIN-1 MEMBERS IN THE HYPOTHALAMUS INCREASES BONE FORMATION
G. C. Rowe*1, H. Saito1, T. Green2, M. Kveiborg3, E. Nestler2, W. C. Horne1, R. Baron1
1Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, 2Psychiatry and Center for Basic Neuroscience, University of Texas Southwestern Medical Center, Dallas, United States, 3Department of Biomedical Sciences and Biotech Research & Innovation Center, University of Copenhagen, Copenhagen, Denmark
11:00 OC41 IMPACT OF BALLOON KYPHOPLASTY ON QUALITY OF LIFE AND RISK OF RECURRENT VERTEBRAL FRACTURES: A RANDOMIZED TRIAL IN PATIENTS WITH ACUTE VERTEBRAL COMPRESSION FRACTURES
S. Boonen*1, S. Cummings2, D. Wardlaw3, R. Eastell4
1Department of Experimental Medicine, Katholieke Universiteit Leuven, Leuven, Belgium, 2Department of Experimental Medicine, University of California, San Francisco, United States, 3Department of Experimental Medicine, Woodend Hospital, Aberdeen, 4Department of Experimental Medicine, University of Sheffield, Sheffield, United Kingdom
11:12 OC42 THE TIMING OF DOSING OF ZOLEDRONIC ACID 5MG AFTER RECENT HIP FRACTURE AFFECTS ANTIFRACTURE EFFICACY AND REDUCTION OF MORTALITY: RESULTS FROM HORIZON-RECURRENT FRACTURE TRIAL
E. F. Eriksen*1, K. W. Lyles2, C. S. Colón-Emeric2, C. F. Pieper3, J. S. Magaziner4, J. D. Adachi5, L. Hyldstrup6, C. Recknor7, L. Nordsletten8, C. Lavecchia9, H. Hu9, S. Boonen10, P. Mesenbrink9
1Clinical Development and Medical Affairs, Novartis Pharma AG, Basel, Switzerland, 2Medicine, 3Biostatistics and Bioinformatics, Duke University Medical Center, Durham, 4Epidemiology, University of Maryland, Baltimore, United States, 5Medicine, McMaster University, Hamilton, Canada, 6Endocrinology, Hvidovre Hospital, Hvidovre, Finland, 7Osteoporosis, United Osteoporosis Centers, Gainesville, United States, 8Orthapaedics, Ullevål University Hospital, Oslo, Norway, 9Clinical Development and Medical Affairs, Novartis Pharmaceuticals Corporation, East Hanover, United States, 10Geriatrics, Katholieke Universiteit Leuven, Leuven, Belgium

 


 

 

 

 

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