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Meet the Professor Richard Oreffo Skeletal Tissue Engineering Topics to be covered Given the demographic challenges of an ageing population combined with rising patient expectation and the growing emphasis placed on cost containment by healthcare providers, skeletal tissue repair is a major clinical and socio-economic need. To this end the application of selected progenitor cells and appropriate scaffolds and growth factors in regenerative strategies is currently one of the most exciting and promising areas for disease treatment and reparative medicine. Critical for translational application from bench to clinic will be the harnessing of interdisciplinary strategies to optimize input around scaffold design and selection, modeling of tissue repair, cell selection and culture and growth factor application. Cell-based strategies for skeletal engineering will also be discussed. Specific areas for discussion will include: i) Principles of Skeletal Tissue Engineering, ii) Cell based strategies, iii) Scaffolds/Matrix, iv) Need for interdisciplinary strategies to deliver from bench to clinic and to include clinical application. Educational goals This session will examine some of the concepts, issues and limitations in skeletal tissue engineering, including cell-based strategies, scaffold design and properties, growth factor application and current translational observations. Target Audience The session will be of interests to basic scientists (pre-doctoral and postdoctoral) as well as trainee orthopaedic fellows with an interest in bone and cartilage regeneration. Teaching methods The session will be interactive and informal - addressing
questions from the audience and developing discussion with participants.
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