Meet the Professor
Frank Luyten
Cell-based therapies: from bench to bedside
Outline of topics
Cell based therapies involves a new field of medical treatments,
quite distinct from the established drug treatments and devices. In this
session we will discuss the critical steps involved in the development
of a cell or combination products, from bench to bedside, including the
characterisation of the product with potency and purity assessments, and
the strengths and limitations of preclinical models. Furthermore, the
challenges for the development of those products and the industrial production
processes will be highlighted. Finally, since many of these treatments
involve applications in regenerative medicine, trial design and outcomes
for musculoskeletal diseases/disorders will be discussed in this context.
Educational goals
- Understand the complexity of cell based therapies
- Provide a number of guidelines for the development of these therapies
- Recognize the need for the upscaling and development of industrial
production processes
- Understand the principle of developmental engineering
Who should attend
Since this subject covers “from bench to bedside”,
a broad audience of basic and translational scientists as well as clinicians
may be interested.
Teaching methods
Interactive discussion with specific examples of
product development in the field of joint resurfacing and bone repair.
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